Valsartan D9
- Product Name
- Valsartan D9
- CAS No.
- 1089736-73-1
- Chemical Name
- Valsartan D9
- Synonyms
- [2H9]-Valsartan;rac-Valsartan D9;D9-Valsartan(major);2H9]-Valsartan(major);Cefuroxime Impurity 73;[2H9]-Valsartan (mixture);ACWBQPMHZXGDFX-KDDXQTGLSA-N;VALSARTAN-D9 (D7-D9 MIXTURE);L-Valine, N-(1-oxopentyl-d9)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-;(2S)-3-methyl-2-[2,2,3,3,4,4,5,5,5-nonadeuteriopentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
- CBNumber
- CB72640030
- Molecular Formula
- C24H29N5O3
- Formula Weight
- 435.53
- MOL File
- 1089736-73-1.mol
Valsartan D9 Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
- form
- A solid
- color
- White to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H361Suspected of damaging fertility or the unborn child
H402Harmful to aquatic life
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 25226
- Product name
- Valsartan-d9
- Purity
- ≥99% deuterated forms (d1-d9)
- Packaging
- 1mg
- Price
- $364
- Updated
- 2024/03/01
- Product number
- V095753
- Product name
- Valsartan-d9(Major)
- Packaging
- 1mg
- Price
- $190
- Updated
- 2021/12/16
- Product number
- 2885DC
- Product name
- ValsartanD9
- Packaging
- 1mg
- Price
- $503
- Updated
- 2021/12/16
- Product number
- BAR0001573
- Product name
- VALSARTAN-D9
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $837.38
- Updated
- 2021/12/16
- Product number
- BAR0001573
- Product name
- VALSARTAN-D9
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $2656.5
- Updated
- 2021/12/16
Valsartan D9 Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
Biological Activity
Valsartan-d9 is intended for use as an internal standard for the quantification of valsartan by GC- or LC-MS. Valsartan is a nonpeptide antagonist of the angiotensin II type 1 (AT1) receptor (IC50 = 2.7 nM). It is 20,000-fold selective for AT1 over AT2 and, unlike some other AT receptor antagonists, does not alter peroxisome proliferator-activated receptor γ (PPARγ) activity in vitro. In vivo, valsartan (30 mg/kg) increases cardiac output and reduces left ventricular fibrosis in a model of heart failure with reduced ejection fraction in mice with streptozotocin-induced diabetes. Formulations containing valsartan have been used in the treatment of hypertension and heart failure.
IC 50
AT1 Receptor
Valsartan D9 Preparation Products And Raw materials
Raw materials
Preparation Products
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