ChemicalBook > CAS DataBase List > 5-BroMo-4-MethoxypyriMidine

5-BroMo-4-MethoxypyriMidine

Product Name
5-BroMo-4-MethoxypyriMidine
CAS No.
4319-85-1
Chemical Name
5-BroMo-4-MethoxypyriMidine
Synonyms
5-BroMo-4-MethoxypyriMidine;Pyrimidine, 5-bromo-4-methoxy-
CBNumber
CB72660975
Molecular Formula
C5H5BrN2O
Formula Weight
189.01
MOL File
4319-85-1.mol
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5-BroMo-4-MethoxypyriMidine Property

Melting point:
72-74 °C
Boiling point:
243.5±20.0 °C(Predicted)
Density 
1.628±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
1.50±0.16(Predicted)
Appearance
White to off-white Solid
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B700653
Product name
5-Bromo-4-methoxypyrimidine
Packaging
500mg
Price
$200
Updated
2021/12/16
AK Scientific
Product number
1103AP
Product name
5-Bromo-4-methoxypyrimidine
Packaging
250mg
Price
$134
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0367009
Product name
5-BROMO-4-METHOXYPYRIMIDINE
Purity
95.00%
Packaging
5MG
Price
$497.93
Updated
2021/12/16
Apolloscientific
Product number
OR959616
Product name
5-bromo-4-methoxypyrimidine
Purity
95%
Packaging
1g
Price
$460
Updated
2021/12/16
Apolloscientific
Product number
OR959616
Product name
5-bromo-4-methoxypyrimidine
Purity
95%
Packaging
250mg
Price
$180
Updated
2021/12/16
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5-BroMo-4-MethoxypyriMidine Chemical Properties,Usage,Production

Synthesis

56181-39-6

124-41-4

4319-85-1

4-Chloro-5-bromopyrimidine (9.90 g, 41.2 mmol) was dissolved in methanol (140 mL) and a methanolic solution of 28% sodium methanolate (24 mL, 120 mmol) was slowly added. The reaction mixture was stirred at 60°C for 15 hours. Upon completion of the reaction, the mixture was allowed to cool to room temperature, diluted with an appropriate amount of water, and subsequently extracted with ethyl acetate. The organic layers were combined, washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate and filtered to remove the desiccant. The filtrate was concentrated under reduced pressure to give 5-bromo-4-methoxypyrimidine (7.72 g, 79% yield) as a light yellow solid.

References

[1] Patent: EP3351533, 2018, A1. Location in patent: Paragraph 0510; 0511

5-BroMo-4-MethoxypyriMidine Preparation Products And Raw materials

Raw materials

Preparation Products

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