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MilbeMycin A3 OxiMe

Product Name
MilbeMycin A3 OxiMe
CAS No.
114177-14-9
Chemical Name
MilbeMycin A3 OxiMe
Synonyms
MilbeMycin A3 OxiMe;Milbemite Impurity 2;5-OxoMilbeMycin A3 oxiMe;5-ketomilbemycin A3 5-oxime;Milbemycin Impurity 10(Milbemycin A3 Oxime);Milbemycin B, 5-demethoxy-28-deoxy-6,28-epoxy-5-(hydroxyimino)-25-methyl-, (6R,25R)-
CBNumber
CB72674901
Molecular Formula
C31H43NO7
Formula Weight
541.68
MOL File
114177-14-9.mol
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MilbeMycin A3 OxiMe Property

storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27967
Product name
Milbemycin A3 oxime
Packaging
1mg
Price
$242
Updated
2024/03/01
Cayman Chemical
Product number
27967
Product name
Milbemycin A3 oxime
Packaging
5mg
Price
$965
Updated
2024/03/01
TRC
Product number
M344298
Product name
MilbemycinA3oxime
Packaging
2.5mg
Price
$475
Updated
2021/12/16
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MilbeMycin A3 OxiMe Chemical Properties,Usage,Production

Description

Milbemycin A3 oxime is an anthelmintic, a derivative of milbemycin A3 , and a component of milbemycin oxide . It reduces the number of microfilariae of the heartworm D. immitis in the blood of naturally infested dogs by 85.2% when administered at a dose of 0.05 mg/kg. Formulations containing milbemycin A3 oxime, in combination with milbemycin A4 oxime, have been used in the treatment of parasitic infections in dogs.

Uses

Milbemycin A3 oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of milbemycin A3. Milbemycin A3 oxime is the minor component (~30%) in the commercial product milbemycin oxime, marketed for endo- and exo-parasite infections. Like the other milbemycin/avermectins, milbemycin A3 oxime acts by opening glutamate sensitive chloride channels in neurons of invertebrates leading to paralysis by hyperpolarisation of these cells and signal transfer blocking.

Uses

Milbemycin A3 oxime is the minor component of the anti-parasitic product milbemycin oxime.

MilbeMycin A3 OxiMe Preparation Products And Raw materials

Raw materials

Preparation Products

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MilbeMycin A3 OxiMe Suppliers

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114177-14-9, MilbeMycin A3 OxiMeRelated Search:

MILBEMECTIN A4 Milbemycin oxime MILBEMECTIN A3 Milbemycin D MilbeMycin A4 OxiMe Miconazole EP Impurity E Milbemycin EP Impurity E Milrinone Impurity 14 Milrinone Impurity 17 5-Decyano 5-(Ethyl Formate) Milrinone Miconazole IMpurity I Miconazole IMpurity B MILRINONE RELATED COMPOUND A (50 MG) (1,6-DIHYDRO-2-METHYL-6-OXO(3,4'-BIPYRIDINE)-5-CAR-BOXAMIDE) 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carboxylic acid 1,6-Dihydro-2-(hydroxyMethyl)-6-oxo-[3,4'-bipyridine]-5-carbonitrile Isoconazole Milbemycin EP Impurity D Milrinone Impurity 13

  • Milbemycin Impurity 10(Milbemycin A3 Oxime)
  • MilbeMycin A3 OxiMe
  • 5-OxoMilbeMycin A3 oxiMe
  • 5-ketomilbemycin A3 5-oxime
  • Milbemycin B, 5-demethoxy-28-deoxy-6,28-epoxy-5-(hydroxyimino)-25-methyl-, (6R,25R)-
  • Milbemite Impurity 2
  • 114177-14-9