1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine

Product Name: 1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine
CAS No.: 1089279-91-3
Chemical Name: 1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine
Synonyms: 1-(4-amino-3-methoxyphenyl)-N,N-dimethyl-4-Piperidinamine;1-(4-amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine;4-Piperidinamine, 1-(4-amino-3-methoxyphenyl)-N,N-dimethyl-;1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine;1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine - [A16491]
CBNumber: CB72677386
Molecular Formula: C14H23N3O
Formula Weight: 249.35
MOL File: 1089279-91-3.mol

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1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine Property

Boiling point:: 421.1±45.0 °C(Predicted)
Density: 1.10±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 9.28±0.20(Predicted)
Appearance: Light brown to brown Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: 2141AQ
Product name: 1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine
Packaging: 5g
Price: $244.4
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM1053731
Product name: 1-(4-AMINO-5-METHOXY-2-METHYLPHENYL)-N,N-DIMETHYLPIPERIDIN-4-AMINE
Purity: 95.00%
Packaging: 5MG
Price: $500.97
Updated: 2021/12/16

AK Scientific

Product number: 2141AQ
Product name: 1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine
Packaging: 25g
Price: $714.8
Updated: 2021/12/16

Ambeed

Product number: A108946
Product name: 1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine
Purity: 96%
Packaging: 100mg
Price: $9
Updated: 2021/12/16

Ambeed

Product number: A108946
Product name: 1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine
Purity: 96%
Packaging: 1g
Price: $36
Updated: 2021/12/16

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1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine Chemical Properties,Usage,Production

Uses

1-(4-Amino-3-methoxyphenyl)-N,N-dimethyl-4-piperidinamine is a useful reagent for organic synthesis.

Synthesis

1089279-90-2

1089279-91-3

General procedure for the synthesis of 1-(4-amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine from BRIGATINIB intermediates: 4.09 g of Compound 29 was added to a reaction flask and dissolved with 40 mL of methanol. Subsequently, 0.4 g of 10% Pd/C catalyst (based on 10% of the mass of Compound 29) was added for the hydrogenation reduction reaction. The progress of the reaction was monitored by TLC and the reaction was complete after about 6 hours. After stopping the reaction, the reaction mixture was filtered and the catalyst was washed with a small amount of methanol. The filtrate was concentrated by distillation under reduced pressure to give 3.38 g of brown solid product 7-6 in 92.60% yield.

References

[1] Patent: CN106905245, 2017, A. Location in patent: Paragraph 0249; 0259; 0260; 0261; 0262
[2] Patent: KR2016/37844, 2016, A. Location in patent: Paragraph 0304; 0306
[3] Patent: EP3372594, 2018, A1. Location in patent: Paragraph 0126; 0128; 0264; 0265
[4] Patent: US2008/300242, 2008, A1. Location in patent: Page/Page column 86
[5] Patent: WO2010/138575, 2010, A1. Location in patent: Page/Page column 82

1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine Suppliers

China 71 India 1 United States 2 Global 74

Adamas Reagent, Ltd.

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View Lastest Price from 1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 1-(4-amino-5-Methoxy-2-Methylphenyl)-N,N-dimethylpiperidin-4-amine 1089279-91-3
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-08-08

Shanghai CRM New Material Technology Co., LTD

Product: 1-(4-amino-5-Methoxy-2-Methylphenyl)-N,N-dimethylpiperidin-4-amine 1089279-91-3
Price: US $10.00-15.00/g
Min. Order: 10g
Purity: 99%
Supply Ability: 10t
Release date: 2022-09-21

Career Henan Chemical Co

Product: 1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine 1089279-91-3
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2019-12-24

1089279-91-3, 1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMineRelated Search:

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1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine - [A16491]

1089279-91-3