GanoMycin I

Product Name: GanoMycin I
CAS No.: 1191255-15-8
Chemical Name: GanoMycin I
Synonyms: GanoMycin I;2(5H)-Furanone, 5-(2,5-dihydroxyphenyl)-3-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-, (5R)-
CBNumber: CB72725412
Molecular Formula: C21H26O4
Formula Weight: 342.43
MOL File: 1191255-15-8.mol

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GanoMycin I Property

Boiling point:: 521.5±50.0 °C(Predicted)
Density: 1.135±0.06 g/cm3(Predicted)
pka: 9.68±0.48(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN92595
Product name: GanomycinI
Packaging: 5mg
Price: $643
Updated: 2021/12/16

Crysdot

Product number: CD32002742
Product name: GanomycinI
Purity: 95+%
Packaging: 5mg
Price: $990
Updated: 2021/12/16

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GanoMycin I Chemical Properties,Usage,Production

Uses

Ganomycin I is a dual inhibitor of α-Glucosidase and HMG-CoA reductase. Ganomycin I can also inhibits HIV protease. Ganomycin I exhibits anti-diabetic and anti-osteoclastogenesis effects[1][2].

References

[1] Tran PT, et, al. Ganomycin I from Ganoderma lucidum attenuates RANKL-mediated osteoclastogenesis by inhibiting MAPKs and NFATc1. Phytomedicine. 2019 Mar 1;55:1-8. DOI:10.1016/j.phymed.2018.10.029
[2] Wang K, et, al. Structural Modification of Natural Product Ganomycin I Leading to Discovery of a α-Glucosidase and HMG-CoA Reductase Dual Inhibitor Improving Obesity and Metabolic Dysfunction in Vivo. J Med Chem. 2018 Apr 26;61(8):3609-3625. DOI:10.1021/acs.jmedchem.8b00107

GanoMycin I Preparation Products And Raw materials

Raw materials

Preparation Products

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GanoMycin I

2(5H)-Furanone, 5-(2,5-dihydroxyphenyl)-3-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-, (5R)-

1191255-15-8