tert-Butyl N-hydroxycarbamate

Product Name: tert-Butyl N-hydroxycarbamate
CAS No.: 36016-38-3
Chemical Name: tert-Butyl N-hydroxycarbamate
Synonyms: tert-Butyl hydroxycarbamate;N-BOC-HYDROXYLAMINE;BOC-NH-OH;BOC-HNOH;N-Boc-hydroxyL;BOC hydroxylamine;N-Boc-Hydroxyamine;N-hydroxycarbamate;N-T-BOC HYDROXYLAMINE;LABOTEST-BB LT00233206
CBNumber: CB7274369
Molecular Formula: C5H11NO3
Formula Weight: 133.15
MOL File: 36016-38-3.mol

More

Less

tert-Butyl N-hydroxycarbamate Property

Melting point:: 53-55 °C (lit.)
Boiling point:: 245.66°C (rough estimate)
Density: 1.2510 (rough estimate)
refractive index: 1.4120 (estimate)
storage temp.: 2-8°C
solubility: Chloroform, Methanol
pka: 9.31±0.23(Predicted)
form: Crystalline Powder
color: White to light pink
Water Solubility: Slightly soluble in water.
Sensitive: Moisture Sensitive
BRN: 1756546
InChI: InChI=1S/C5H11NO3/c1-5(2,3)9-4(7)6-8/h8H,1-3H3,(H,6,7)
InChIKey: DRDVJQOGFWAVLH-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)NO
CAS DataBase Reference: 36016-38-3(CAS DataBase Reference)

More

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 21
HS Code: 29280090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 226157
Product name: N-Boc-hydroxylamine
Purity: ≥98%
Packaging: 5g
Price: $97.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 226157
Product name: N-Boc-hydroxylamine
Purity: ≥98%
Packaging: 1g
Price: $26
Updated: 2023/06/20

TCI Chemical

Product number: H0848
Product name: tert-Butyl N-Hydroxycarbamate
Purity: >98.0%(GC)
Packaging: 5g
Price: $17
Updated: 2024/03/01

TCI Chemical

Product number: H0848
Product name: tert-Butyl N-Hydroxycarbamate
Purity: >98.0%(GC)
Packaging: 25g
Price: $34
Updated: 2024/03/01

Alfa Aesar

Product number: A10349
Product name: N-Boc-hydroxylamine, 98+%
Packaging: 1g
Price: $27.65
Updated: 2024/03/01

More

Less

tert-Butyl N-hydroxycarbamate Chemical Properties,Usage,Production

Chemical Properties

White to light pink crystalline powder

Uses

N-Boc-hydroxylamine is used in the preparation of azridines by cycloaddition of azides with nitroso Diels-Alder adducts. It acts as a reagent for the synthesis of hydroxylamine derivatives t-butyl-N-(acyloxy)carbamates and N,O-diacylated N-hydroxyarylsulfonamides.

Uses

tert-Butyl N-hydroxycarbamate is used in the preparation of azridines by cycloaddition of azides with nitroso Diels-Alder adducts.

Synthesis Reference(s)

Journal of the American Chemical Society, 81, p. 955, 1959 DOI: 10.1021/ja01513a049
Tetrahedron Letters, 24, p. 231, 1983 DOI: 10.1016/S0040-4039(00)81372-6

Synthesis

A suspension of NH2OH·HCl (9.7 g, 140mmol) and K2CO3 (9.7 g, 700 mmol) in Et2O (60 mL) and H2O (2 mL)was stirred for about 1 h at r.t. with evolution of CO2 gas. A solution of Boc2O (20.0 g, 92 mmol) in Et2O (40 mL) was then added dropwise at 0 °C, and the suspension was stirred at r.t for 12 h. The organic phase was decanted, and the solid was washed with Et2O (3 × 30 mL). The combined organic layers were concentrated, and the residue was recrystallized from cyclohexane/toluene to afford the desired product tert-butyl N-hydroxycarbamate as a white solid.

tert-Butyl N-hydroxycarbamate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

tert-Butyl N-hydroxycarbamate Suppliers

Americas 1 Belgium 3 Canada 1 China 271 Europe 1 Germany 8 India 34 Japan 7 Switzerland 2 The Netherlands 1 United Kingdom 15 United States 53 Global 397

Suzhou Highfine Biotech Co., Ltd

Tel: 0512-68311833 13962195826
Fax: 0512-68417696
Email: wuhao@highfine.com
Country: China
ProdList: 499
Advantage: 75

Shanghai Qiude Biochemical Engineering Co., Ltd

Tel: 021-37285021 13472570865;
Fax: 86-021-51714507
Email: info@pure-chiral.com
Country: China
ProdList: 304
Advantage: 64

Z IntellecChem & Tech. Co., Ltd

Tel: 13179383568; 15050866711
Fax: QQ:2677337387
Email: contact@zintellec.com
Country: China
ProdList: 390
Advantage: 58

Shandong Yukun Chemical Industry Co. LTD

Tel: 18660690289
Email: sales@yukunchem.com
Country: China
ProdList: 45
Advantage: 58

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

Tel: 15523000485
Email: xingcanyaoye@sina.com
Country: China
ProdList: 1686
Advantage: 58

BTC Pharmaceutical CO. Ltd

Tel: 0513-0513-68015397 18862996710
Fax: 0513-68015394
Email: sales12@btcpharm.com
Country: China
ProdList: 689
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 4986
Advantage: 55

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

More

Less

View Lastest Price from tert-Butyl N-hydroxycarbamate manufacturers

Xiamen Yunfan Biotech Co.,Ltd.

Product: tert-Butyl N-hydroxycarbamate 36016-38-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%+
Supply Ability: 1200kg/Month
Release date: 2024-05-14

Zibo Hangyu Biotechnology Development Co., Ltd

Product: tert-Butyl N-hydroxycarbamate 36016-38-3
Price: US $70.00-700.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-06

Henan Fengda Chemical Co., Ltd

Product: tert-Butyl N-hydroxycarbamate 36016-38-3
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

36016-38-3, tert-Butyl N-hydroxycarbamateRelated Search:

Buprofezin Butyl acetate tert-Butyl glycinate tert-Butyl 4-aminobenzoate Butyl formate n-Butyl carbamate tert-Butanol 2-Butoxyethanol Hydroxylamine hydrochloride Hydroxylamine sulfate tert-Butyl carbazate Urethane tert-Butyl peroxybenzoate 4-Aminobenzoic acid N-Carbobenzyloxyglycine 4-Hydroxybenzoic acid Cyhalofop-butyl Methylparaben

N-Boc-hydroxylamine, >=98%

N-tert-Butoxycarbonylhydroxylamine, 98+%

N-(tert-Butoxycarbonyl)hydroxylamine~tert-ButylN-hydroxycarbamate

N-(T-BUTOXYCARBONYL)-HYDROXYLAMINE

N-T-BOC HYDROXYLAMINE

N-HYDROXYCARBAMIC ACID TERT-BUTYL ESTER

N-BOC-HYDROXYLAMINE

TERT-BUTYL N-HYDROXYCARBAMATE 99.0%

N-Boc-Hydroxyamine

T-BUTYL N-HYDROXYCARBOMATE (N-BOC HYDROXYLAMINE)

T-BUTYL N-HYDROXYCARBOMATE

PNB(4R,5S,6S)-3-(diphenyloxy)phosphoryloxy-6[(1R)-1-hydoxyethyl]-4-methyl -7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-caboxylate(MAP or MVP)

(t-Butoxycarbonyl)-hydroxylamine

N-t-Butyloxycarbonyl-hydroxylamine

N-Boc-hydroxylamine N-(tert-Butoxycarbonyl)hydroxylamine N-Hydroxycarbamic Acid tert-Butyl Ester

N-hydroxy-, 1,1-dimethylethyl ester

Carbamic acid, hydroxy-, 1,1-dimethylethyl ester

(Hydroxyamino)formic acid tert-butyl ester

tert-Butyl hydroxycarbamate

<i>tert</i>-Butyl <i>N</i>-hydroxycarbamate

BOC-HNOH

BOC-NH-OH

T-BUTYL N-HYDROXYCARBAMATE

TERT-BUTYL N-HYDROXYCARBAMATE

LABOTEST-BB LT00233206

N-(TERT-BUTYLOXYCARBONYL)HYDROXYLAMINE

N-TERT-BUTOXYCARBONYLHYDROXYLAMINE

BOC-Hydroxylamine Tert-Butyl N-hydroxycarbamate

Carbamic acid,N-hydroxy-, 1,1-dimethylethyl ester

N-Boc-hydroxylamine≥ 99% (HPLC)

N-tert-BOC-Hydroxylamine for synthesis

N-(tert-Butoxycarbonyl)hyd

BOC hydroxylamine

4-hydroxy-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]butanoic acid

n-hydroxycarbamate tert butyl ester

tert-ButylN-Hydroxycarbamate&gt

N-Boc-hydroxyL

N-hydroxycarbamate

ert-ButylN-hydroxycarbamate

N-tert-Boc-Hydroxylamine

36016-38-3

C5H11O3N

CH33COCONHOH

Hydroxylamines

Hydroxylamines (N-Substituted)

Building Blocks

Organic Building Blocks

Nitrogen Compounds

Protected Amines

Hydroxylamines

Hydroxylamines (N-Substituted)

Naphthyridine,Quinoline

API intermediates

INTERMEDIATESOFMEROPENAM

1