2,4-Dimethyl aniline Property

Melting point:

16 °C

Boiling point:

218 °C(lit.)

Density 

0.98 g/mL at 25 °C(lit.)

vapor density 

4.2 (vs air)

vapor pressure 

0.16 mm Hg ( 25 °C)

refractive index 

n20/D 1.558(lit.)

Flash point:

195 °F

storage temp. 

room temp

solubility 

5g/l

form 

Liquid

pka

pK1:4.89(+1) (25°C)

color 

Clear yellow to red-brown

PH

7 (22g/l, H2O, 20℃)

Odor

Amine like

explosive limit

1.1-7.0%(V)

Water Solubility 

5 g/L (20 ºC)

Merck 

14,10084

BRN 

636243

Dielectric constant

4.9000000000000004

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides, chloroformates, halogens.

LogP

2.02 at 23℃ and pH8

CAS DataBase Reference

95-68-1(CAS DataBase Reference)

NIST Chemistry Reference

Benzenamine, 2,4-dimethyl-(95-68-1)

IARC

3 (Vol. 16, Sup 7) 1987

EPA Substance Registry System

2,4-Dimethylaniline (95-68-1)

Safety

Hazard Codes 

T,N

Risk Statements 

23/24/25-33-51/53

Safety Statements 

28-36/37-45-61-28A

RIDADR 

UN 1711 6.1/PG 2

WGK Germany 

2

RTECS 

ZE8925000

F 

8

Autoignition Temperature

860 °F

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29214910

Hazardous Substances Data

95-68-1(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P314Get medical advice/attention if you feel unwell.

2,4-Dimethyl aniline Chemical Properties,Usage,Production

Chemical Properties

colourless to yellow or dark brown liquid

Uses

2,4-Xylidine, as part of the commercial mixture, has the same uses as xylidine.

Definition

ChEBI: A primary arylamine that is aniline in which the hydrogens at the 2- and 4-positions are replaced by methyl groups. A clear to yellow liquid, it is used in production of certain dyes, pesticides and other chemicals.

General Description

Dark brown liquid.

Air & Water Reactions

2,4-Dimethyl aniline may be sensitive to prolonged exposure to air. Slightly soluble in water.

Reactivity Profile

2,4-Dimethyl aniline ignites on contact with fuming nitric acid . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

2,4-Dimethyl aniline is combustible.

Safety Profile

Suspected carcinogen. Poison by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also other xylidine entries.

Metabolic pathway

The major urinary metabolite of 2,4-dimethylaniline (2,4-DMA) in rats is N-acetyl-4-amino-3-methylbenzoic acid, while in dogs, it is 6-hydroxy-2,4-dimethylaniline. Dogs also produce a smaller amount of unacetylated 4-amino-3-methylbenzoic acid and its glycine conjugate. 2,6-Dimethylaniline (2,6-DMA) is metabolized principally to 4-hydroxy-2,6- dimethylaniline in both species, but dogs also produce a significant quantity of 2-amino-3-methylbenzoic acid along with a trace amount of the glycine conjugate of the latter metabolite and 2,6-dimethylnitrosobenzene. Trace levels of an unknown postulated to be 3,5- dimethyl-4-iminoquinone are found in dog urine.

Purification Methods

Convert uns-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry it over KOH and fractionally distil. The acetyl derivative has m 130o, the benzoyl derivative has m 192o, and the picrate has m 209o. [Beilstein 12 H 1111, 12 IV 2545.]