ChemicalBook > CAS DataBase List > 2-METHYL-6-NITROBENZOIC ACID

2-METHYL-6-NITROBENZOIC ACID

Product Name: 2-METHYL-6-NITROBENZOIC ACID
CAS No.: 13506-76-8
Chemical Name: 2-METHYL-6-NITROBENZOIC ACID
Synonyms: RARECHEM AL BO 0232;6-NITRO-O-TOLUIC ACID;Methyl-6-nitrobenzoic;2-Carboxy-3-nitrotoluene;2-Methyl-nitrobenzoic Acid;2-Methyl-6-nitrobenzoicAci;2-METHYL-6-NITROBENZOIC ACID;2-NITRO-6-METHYLBENZOIC ACID;6-Nitro-2-methylbenzoic acid;2-Methyl-6-nitrobenzonic acid
CBNumber: CB7290493
Molecular Formula: C8H7NO4
Formula Weight: 181.15
MOL File: 13506-76-8.mol

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2-METHYL-6-NITROBENZOIC ACID Property

Melting point:: 153-157 °C (lit.)
Boiling point:: 314.24°C (rough estimate)
Density: 1.4283 (rough estimate)
refractive index: 1.5468 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO, Methanol
form: Solid
pka: pK1:1.87 (25°C)
color: Pale Yellow
BRN: 2050804
InChI: InChI=1S/C8H7NO4/c1-5-3-2-4-6(9(12)13)7(5)8(10)11/h2-4H,1H3,(H,10,11)
InChIKey: CCXSGQZMYLXTOI-UHFFFAOYSA-N
SMILES: C(O)(=O)C1=C([N+]([O-])=O)C=CC=C1C
CAS DataBase Reference: 13506-76-8(CAS DataBase Reference)
EPA Substance Registry System: 2-Methyl-6-nitrobenzoic acid (13506-76-8)

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Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 22-24/25
WGK Germany: 3
HS Code: 29163990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 151394
Product name: 2-Methyl-6-nitrobenzoic acid
Purity: 97%
Packaging: 25g
Price: $548
Updated: 2023/01/07

TCI Chemical

Product number: M1002
Product name: 2-Methyl-6-nitrobenzoic Acid
Purity: >98.0%(T)
Packaging: 10g
Price: $96
Updated: 2025/07/31

TCI Chemical

Product number: M1002
Product name: 2-Methyl-6-nitrobenzoic Acid
Purity: >98.0%(T)
Packaging: 25g
Price: $186
Updated: 2025/07/31

TRC

Product number: M325545
Product name: 2-Methyl-nitrobenzoicAcid
Packaging: 100g
Price: $625
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 52332
Product name: 2-Methyl-nitrobenzoicAcid
Packaging: 25g
Price: $690
Updated: 2021/12/16

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2-METHYL-6-NITROBENZOIC ACID Chemical Properties,Usage,Production

Chemical Properties

light orange to yellow-brown crystalline powder

Uses

2-Methyl-nitrobenzoic acid acts as herbicide due to the anthranilic acid moiety within the substructure.

General Description

Pale yellow needles or tan powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-METHYL-6-NITROBENZOIC ACID is a nitrated carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.

Fire Hazard

Flash point data for 2-METHYL-6-NITROBENZOIC ACID are not available; however, 2-METHYL-6-NITROBENZOIC ACID is probably combustible.

Synthesis

83-41-0

13506-76-8

The general procedure for the synthesis of 2-methyl-6-nitrobenzoic acid from 3-nitro-o-xylene was as follows: 1,2-dimethyl-3-nitrobenzene (453 mg, 3 mmol, 1.0 eq.) was added to a 100 mL autoclave with sodium hydroxide (0.9 g, 22.5 mmol, 7.5 eq.), followed by the addition of 5 mL of ethanol. After passing oxygen three times, the oxygen pressure was maintained at 1.8 MPa and the reaction was carried out in an oil bath at 65°C for 24 hours. Upon completion of the reaction, the reaction mixture was diluted with methanol and the pH was adjusted to 6-7 for neutralization. After removing the solvent under reduced pressure, ethyl acetate was added and the mixture was dried. Separation by column chromatography gave 47 mg (0.31 mmol) of unreacted 1,2-dimethyl-3-nitrobenzene with 90% conversion. The target product 2-methyl-6-nitrobenzoic acid 350 mg (1.93 mmol) was also obtained in 64% yield.

References

[1] Patent: CN106995374, 2017, A. Location in patent: Paragraph 0121; 0122; 0123
[2] Journal of Organic Chemistry, 2018, vol. 83, # 15, p. 8092 - 8103

2-METHYL-6-NITROBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-METHYL-6-NITROBENZOIC ACID manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-METHYL-6-NITROBENZOIC ACID 13506-76-8
Price: US $10.00-8.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-14

Henan Fengda Chemical Co., Ltd

Product: 2-METHYL-6-NITROBENZOIC ACID 13506-76-8
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-25

Hebei Fengqiang Trading Co., LTD

Product: 2-METHYL-6-NITROBENZOIC ACID 13506-76-8
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2023-06-13

13506-76-8, 2-METHYL-6-NITROBENZOIC ACIDRelated Search:

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6-NITRO-O-TOLUIC ACID

2-NITRO-6-METHYLBENZOIC ACID

2-METHYL-6-NITROBENZOIC ACID

RARECHEM AL BO 0232

Benzoic acid, 2-methyl-6-nitro-

2-METHYL-6-NITROBENZOIC ACID / 6-NITRO-O-TOLUIC ACID

6-Nitro-o-toluic acid (COOH=1)

2-METHYL-6-NITROBENZOIC ACID 98+%

6-Nitro-2-methylbenzoic acid

2-Methyl-6-nitrobenzoic acid,99%

2-Carboxy-3-nitrotoluene

2-Methyl-6-nitrobenzonic acid

2-Methyl-nitrobenzoic Acid

Methyl-6-nitrobenzoic

2-Methyl-6-nitrobenzoicAcid&gt

2-Methyl-6-nitrobenzoicAci

2-METHYL-6-NITROBENZOIC ACID ISO 9001：2015 REACH

2-Methyl-6-nitrobenzoic acid or 6-Nitro-o-toluic Acid

13506-76-8

Organic Building Blocks

CARBOXYLIC ACID

Building Blocks

Carbonyl Compounds

Carboxylic Acids

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts