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Pirarubicin

Product Name
Pirarubicin
CAS No.
72496-41-4
Chemical Name
Pirarubicin
Synonyms
Therarubicin;PIRARUBICIN HYDROCHLORIDE;(8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione;(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione;CS-702;1609rb;THP-ADM;Pirabucin;Pirarubcin;THEPRUBICIN
CBNumber
CB7315796
Molecular Formula
C32H37NO12
Formula Weight
627.64
MOL File
72496-41-4.mol
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Pirarubicin Property

Melting point:
188-192°C (dec.)
alpha 
D25 +175 ±25° (c = 0.2 in CHCl3)
Boiling point:
834.7±65.0 °C(Predicted)
Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
ethanol: soluble25mg/mL
form 
powder
pka
7.35±0.60(Predicted)
color 
Orange to Red
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
RTECS 
QI9296000
Toxicity
LD50 i.v. in mice: 27.8 mg/kg (Umezawa, 1979)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H340May cause genetic defects

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P8624
Product name
Pirarubicin
Purity
≥95% (HPLC)
Packaging
10mg
Price
$432
Updated
2023/06/20
Sigma-Aldrich
Product number
P8624
Product name
Pirarubicin
Purity
≥95% (HPLC)
Packaging
25mg
Price
$863
Updated
2023/06/20
Cayman Chemical
Product number
28384
Product name
Pirarubicin
Packaging
10mg
Price
$84
Updated
2024/03/01
Cayman Chemical
Product number
28384
Product name
Pirarubicin
Packaging
100mg
Price
$638
Updated
2024/03/01
Cayman Chemical
Product number
28384
Product name
Pirarubicin
Packaging
5mg
Price
$44
Updated
2024/03/01
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Pirarubicin Chemical Properties,Usage,Production

Description

Pirarubicin is a new anthracycline anticancer agent structurally related to doxorubicin. In acute leukemia, non-Hodgkin’s lymphoma, breast and ovariail carcinoma, pirarubicin is reportedly superior to doxorubicin and better tolerated. Its major side-effect appears to be myelosuppression, mainly in the form of leucopenia, which is potentially dose-limiting.

Chemical Properties

Red Solid

Originator

Meiji Seika (Japan)

Uses

Structural analog of Doxorubicin. Antineoplastic.

Definition

ChEBI: (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione is an anthracycline.

brand name

Pinorubicin; Therarubucin

Pirarubicin Preparation Products And Raw materials

Raw materials

Preparation Products

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Pirarubicin Suppliers

Shanghai Mokai Pharmaceutical Technology Co., Ltd.
Tel
021-60951261 18601606476
Email
nancy@mkpharma.cn
Country
China
ProdList
453
Advantage
58
Jiangxi ravel Biotechnology Co.,Ltd
Tel
18502762009
Email
721846333@qq.com
Country
China
ProdList
2441
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
Advantage
61
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2127
Advantage
70
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5700
Advantage
66
Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd
Tel
010-53679529 13801208576
Fax
010-64215766
Email
sales.2@chinazhongshuo.com
Country
China
ProdList
100
Advantage
65
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
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View Lastest Price from Pirarubicin manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
Pirarubicin 72496-41-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-03
Hebei Guanlang Biotechnology Co., Ltd.
Product
Pirarubicin 72496-41-4
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-05-14
Wuhan Demeikai Biotechnology Co., Ltd
Product
Pirarubicin 72496-41-4
Price
US $10.00/g/Bag
Min. Order
10g
Purity
99
Supply Ability
100KG
Release date
2021-11-16

72496-41-4, PirarubicinRelated Search:


  • THP-ADM
  • THEPRUBICIN
  • (8s-cis)-droxyacetyl)-1-methoxy
  • (8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
  • Tepirubicin
  • Therarubiein
  • THP-adriamycin
  • (8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
  • 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-alpha-L- lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
  • (8S)-10α-[[3-Amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
  • (8S,10S)-10α-[[3-Amino-4-O-(tetrahydro-2H-pyran-2-yl)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-hydroxyacetyl-1-methoxy-5,12-naphthacenedione
  • Pirarubicin(THP-AdriaMycin)
  • (7S,9S)-7-((2R,4S,5S,6S)-4-amino-6-methyl-5-((R)-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
  • PIRARUBICIN
  • PIRARUBICIN HYDROCHLORIDE
  • CS-702
  • Pirarubcin
  • 1609rb
  • 4’-o-tetrahydropyranyladriamycin
  • 4’-o-tetrahydropyranyldoxorubicin
  • 5,12-naphthacenedione,10-((3-amino-2,3,6-trideoxy-4-o-(tetrahydro-2h-pyran-2-y
  • l)-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hy
  • Pirarubicin(BICINS)
  • (8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
  • Pinorubicin
  • Therarubicin
  • Pirabucin
  • 5,12-Naphthacenedione, 10-3-amino-2,3,6-trideoxy-4-O-(2R)-tetrahydro-2H-pyran-2-yl-.alpha.-L-lyxo-hexopyranosyloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
  • (8S)-10-[(2S,4S,5S,6S)-4-amino-6-methyl-5-[(2R)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
  • 5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-
  • Pirarubicin USP/EP/BP
  • (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-6-methyl-5-(((R)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
  • Pirarubicin Topoisomerase II inhibitor ab142734
  • Famoxadone Impurity 14
  • THP-Doxorubicin
  • 72496-41-4
  • C32H37NO12
  • Inhibitors
  • API
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Chiral Reagents