Pirarubicin

Product Name: Pirarubicin
CAS No.: 72496-41-4
Chemical Name: Pirarubicin
Synonyms: Therarubicin;PIRARUBICIN HYDROCHLORIDE;(8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione;(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione;CS-702;1609rb;THP-ADM;Pirabucin;Pirarubcin;THEPRUBICIN
CBNumber: CB7315796
Molecular Formula: C32H37NO12
Formula Weight: 627.64
MOL File: 72496-41-4.mol

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Pirarubicin Property

Melting point:: 188-192°C (dec.)
alpha: D25 +175 ±25° (c = 0.2 in CHCl3)
Boiling point:: 834.7±65.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: ethanol: soluble25mg/mL
form: powder
pka: 7.35±0.60(Predicted)
color: Orange to Red
Stability:: Hygroscopic

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
RTECS: QI9296000
Toxicity: LD50 i.v. in mice: 27.8 mg/kg (Umezawa, 1979)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H340May cause genetic defects

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P8624
Product name: Pirarubicin
Purity: ≥95% (HPLC)
Packaging: 10mg
Price: $432
Updated: 2023/06/20

Sigma-Aldrich

Product number: P8624
Product name: Pirarubicin
Purity: ≥95% (HPLC)
Packaging: 25mg
Price: $863
Updated: 2023/06/20

Cayman Chemical

Product number: 28384
Product name: Pirarubicin
Packaging: 10mg
Price: $84
Updated: 2024/03/01

Cayman Chemical

Product number: 28384
Product name: Pirarubicin
Packaging: 100mg
Price: $638
Updated: 2024/03/01

Cayman Chemical

Product number: 28384
Product name: Pirarubicin
Packaging: 5mg
Price: $44
Updated: 2024/03/01

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Pirarubicin Chemical Properties,Usage,Production

Description

Pirarubicin is a new anthracycline anticancer agent structurally related to doxorubicin. In acute leukemia, non-Hodgkin’s lymphoma, breast and ovariail carcinoma, pirarubicin is reportedly superior to doxorubicin and better tolerated. Its major side-effect appears to be myelosuppression, mainly in the form of leucopenia, which is potentially dose-limiting.

Chemical Properties

Red Solid

Originator

Meiji Seika (Japan)

Uses

Structural analog of Doxorubicin. Antineoplastic.

Definition

ChEBI: (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione is an anthracycline.

brand name

Pinorubicin; Therarubucin

Pirarubicin Preparation Products And Raw materials

Raw materials

Doxorubicin hydrochloride Adriamycin Silica gel Tetrahydropyran

Preparation Products

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Pirarubicin Suppliers

Canada 1 China 210 Europe 4 Germany 2 India 4 Japan 1 Switzerland 1 United Kingdom 6 United States 32 Global 261

Shanghai Mokai Pharmaceutical Technology Co., Ltd.

Tel: 021-60951261 18601606476
Email: nancy@mkpharma.cn
Country: China
ProdList: 453
Advantage: 58

Jiangxi ravel Biotechnology Co.,Ltd

Tel: 18502762009
Email: 721846333@qq.com
Country: China
ProdList: 2448
Advantage: 58

Hubei wei shi reagent group ltd., company

Tel: 027-59102966 18717199209
Fax: 027-59379337
Email: 2853877583@qq.com
Country: China
ProdList: 3110
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

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View Lastest Price from Pirarubicin manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Pirarubicin 72496-41-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-19

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Pirarubicin 72496-41-4
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 100kg/Month
Release date: 2024-10-11

Hebei Mojin Biotechnology Co., Ltd

Product: Pirarubicin 72496-41-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-07-03

72496-41-4, PirarubicinRelated Search:

Doxorubicinone Chrysophanic acid Idarubicin hydrochloride Adriamycin 2-(HYDROXYMETHYL)ANTHRAQUINONE Pirarubicin 1,8-Dihydroxyanthraquinone 1,2,3,4-TETRAHYDRO-1,5-NAPHTHALENEDIOL 3,4-DIMETHYL-3'-METHOXYBENZOPHENONE 2-METHOXY-4'-METHYLBENZOPHENONE 2-METHOXY-3'-METHYLBENZOPHENONE 14-Hydroxy Carminomycin 2,4-DIMETHYL-3'-METHOXYBENZOPHENONE Carubicin 4-ETHYL-2'-METHOXYBENZOPHENONE L-DaunosamineHCl 3-METHOXY-3'-METHYLBENZOPHENONE ISLANDICIN

THP-ADM

THEPRUBICIN

(8s-cis)-droxyacetyl)-1-methoxy

(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

Tepirubicin

Therarubiein

THP-adriamycin

(8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione

5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-alpha-L- lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-

(8S)-10α-[[3-Amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

(8S,10S)-10α-[[3-Amino-4-O-(tetrahydro-2H-pyran-2-yl)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-hydroxyacetyl-1-methoxy-5,12-naphthacenedione

Pirarubicin(THP-AdriaMycin)

(7S,9S)-7-((2R,4S,5S,6S)-4-amino-6-methyl-5-((R)-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

PIRARUBICIN

PIRARUBICIN HYDROCHLORIDE

CS-702

Pirarubcin

1609rb

4’-o-tetrahydropyranyladriamycin

4’-o-tetrahydropyranyldoxorubicin

5,12-naphthacenedione,10-((3-amino-2,3,6-trideoxy-4-o-(tetrahydro-2h-pyran-2-y

l)-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hy

Pirarubicin(BICINS)

(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

Pinorubicin

Therarubicin

Pirabucin

5,12-Naphthacenedione, 10-3-amino-2,3,6-trideoxy-4-O-(2R)-tetrahydro-2H-pyran-2-yl-.alpha.-L-lyxo-hexopyranosyloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-

(8S)-10-[(2S,4S,5S,6S)-4-amino-6-methyl-5-[(2R)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione

5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-

Pirarubicin USP/EP/BP

(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-6-methyl-5-(((R)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

Pirarubicin Topoisomerase II inhibitor ab142734

THP-Doxorubicin

Theprubicin|||THP

Famoxadone Impurity 14

72496-41-4

C32H37NO12

Inhibitors

API

Intermediates & Fine Chemicals

Pharmaceuticals

Chiral Reagents