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DNP-PEG3-azide

Product Name
DNP-PEG3-azide
CAS No.
951671-87-7
Chemical Name
DNP-PEG3-azide
Synonyms
N3-PEG3-DNP;DNP-PEG3-N3;DNP-PEG3-azide;Reaxys ID: 11170481;N-(2-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)ethyl)-2,4-dinitroaniline
CBNumber
CB73162944
Molecular Formula
C14H20N6O7
Formula Weight
384.35
MOL File
951671-87-7.mol
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DNP-PEG3-azide Property

storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in DMSO, DCM, DMF
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23248
Product name
DNP-PEG3-azide
Purity
98%
Packaging
100mg
Price
$290
Updated
2021/12/16
BroadPharm
Product number
BP-23248
Product name
DNP-PEG3-azide
Purity
98%
Packaging
250mg
Price
$480
Updated
2021/12/16
BroadPharm
Product number
BP-23248
Product name
DNP-PEG3-azide
Purity
98%
Packaging
500mg
Price
$750
Updated
2021/12/16
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DNP-PEG3-azide Chemical Properties,Usage,Production

Description

DNP-PEG3-azide is a PEG linker containing DNP and azide moieties. DNP is involved in biological applications such as participating in ion transport across membranes. The azide can react with alkynes, DBCO and BCN in copper-catalyzed Click Chemistry reactions. The hydrophilic PEG spacer increases the water solubility of the compound in aqueous media.

Uses

DNP-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DNP-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DNP-PEG3-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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DNP-PEG3-azide Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
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View Lastest Price from DNP-PEG3-azide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
DNP-PEG3-N3 951671-87-7
Price
US $0.00/mg
Min. Order
500mg
Purity
>98.00%
Supply Ability
500mg
Release date
2024-03-25