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Steviol

Product Name
Steviol
CAS No.
471-80-7
Chemical Name
Steviol
Synonyms
Stevioside;HYDROXYDEHYDROSTEVIC ACID;(4R)-13-Hydroxykaur-16-en-18-oic acid;2,3,4,4aα,4b,5,6,7,8,8aα,9,10-Dodecahydro-2β-hydroxy-4bβ,8α-dimethyl-12-methylene-1H-2α,10aα-ethanophenanthrene-8β-carboxylic acid;STEVIOL;STEVIOL(P);NSC 226902;Steviol-RM;(-)-Steviol;Steviol Standard
CBNumber
CB7338425
Molecular Formula
C20H30O3
Formula Weight
318.45
MOL File
471-80-7.mol
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Steviol Property

Melting point:
215°
alpha 
D -94.7°
Boiling point:
464.5±45.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO: >10mg/mL
form 
powder
pka
4.65±0.60(Predicted)
color 
white to tan
Stability:
Light Sensitive
InChIKey
QFVOYBUQQBFCRH-ZPNQOMQUSA-N
LogP
4.035 (est)
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Safety

WGK Germany 
3
RTECS 
NZ8176000
HS Code 
29181990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H8664
Product name
Steviol hydrate
Purity
≥98% (HPLC), powder
Packaging
10mg
Price
$247
Updated
2024/03/01
Sigma-Aldrich
Product number
19345
Product name
Steviol
Purity
analytical standard
Packaging
10mg
Price
$343
Updated
2022/05/15
Cayman Chemical
Product number
10011344
Product name
Steviol
Purity
≥98%
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
10011344
Product name
Steviol
Purity
≥98%
Packaging
10mg
Price
$161
Updated
2024/03/01
Sigma-Aldrich
Product number
H8664
Product name
Steviol hydrate
Purity
≥98% (HPLC), powder
Packaging
50mg
Price
$1110
Updated
2024/03/01
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Steviol Chemical Properties,Usage,Production

Uses

Steviol is an aglycone of the natural sweetener Stevioside (90%, S686730) and is found to be highly mutagenic compared to Stevioside.

Uses

Has been proposed as non-nutritive sweetening agent.

Definition

ChEBI: Steviol is an ent-kaurane diterpenoid that is 5beta,8alpha,9beta,10alpha-kaur-16-en-18-oic acid in which the hydrogen at position 13 has been replaced by a hydroxy group. It has a role as an antineoplastic agent. It is a tetracyclic diterpenoid, a tertiary allylic alcohol, a monocarboxylic acid, a bridged compound and an ent-kaurane diterpenoid. It is a conjugate acid of a steviol(1-).

Health Hazard

Steviol has been reported to be mutagenic.Wide use of stevia in Japan for >30 years did not produce any known deleterious side effects. In Japan, enzymatically glycosylated blend of stevioside and rebaudioside A, which appears to impart a cleaner taste profile, is also available commercially.

Biochem/physiol Actions

Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance.

Steviol Preparation Products And Raw materials

Raw materials

Preparation Products

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Steviol Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from Steviol manufacturers

Aurora Industry Co., Ltd.
Product
Stevia Extract 471-80-7
Price
US $26.00/kg
Min. Order
100kg
Purity
95%
Supply Ability
50 tons
Release date
2024-09-13
Shaanxi Dideu Medichem Co. Ltd
Product
Steviol 471-80-7
Price
US $1.00-22.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000KG
Release date
2024-08-01
Shanghai Standard Technology Co., Ltd.
Product
Steviol 471-80-7
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
100 g
Release date
2020-08-19

471-80-7, SteviolRelated Search:


  • Steviol glycoside with 80-95% stevioside
  • STEVIOL(P)
  • Steviol hydrate
  • ent-13-Hydroxykauran-16-en-19-oic acid
  • NSC 226902
  • Kaur-16-en-18-oic acid,13-hydroxy-, (4a)-
  • Steviol, 98%, from Stevia rebaudiana
  • Stevioside 471-80-7
  • (4alpha)-13-Hydroxykaur-16-en-18-oic acid
  • Stevioside
  • STEVIOL
  • 1H-2,10a-Ethanophenanthrene
  • (4α)-13-Hydroxykaur-16-en-18-oic acid
  • (4R)-13-Hydroxykaur-16-en-18-oic acid
  • 2,3,4,4aα,4b,5,6,7,8,8aα,9,10-Dodecahydro-2β-hydroxy-4bβ,8α-dimethyl-12-methylene-1H-2α,10aα-ethanophenanthrene-8β-carboxylic acid
  • 13-HYDROXYKAUR-16-EN-18-OIC ACID
  • (14-alpha)-13-hydroxykaur-16-en-18-oicacid
  • (14-alpha)-kaur-16-en-18-oicaci
  • 13-hydroxy-kaur-16-en-18-oicaci
  • HYDROXYDEHYDROSTEVIC ACID
  • Steviol Standard
  • Steviol USP/EP/BP
  • Stevioside,Steviol hydrate
  • (4R,4aS,6aR,9S,11aR,11bS)-9-Hydroxy-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid
  • Kaur-16-en-18-oic acid, 13-hydroxy-, (4α)-
  • (-)-Steviol
  • NSC 226902|||Hydroxydehydrostevic acid
  • Steviol-RM
  • Ramelteon Impurity 28-d3
  • 471-80-7
  • standard substance
  • reagent
  • Natural Plant Extract