5-BROMO-2-(METHYLAMINO)PYRIMIDINE
- Product Name
- 5-BROMO-2-(METHYLAMINO)PYRIMIDINE
- CAS No.
- 31402-54-7
- Chemical Name
- 5-BROMO-2-(METHYLAMINO)PYRIMIDINE
- Synonyms
- 5-BROMO-2-(METHYLAMINO);5-Bromo-2-(methylamino)pyridine;5-BROMO-2-(METHYLAMINO)PYRIMIDINE;5-Bromo-N-methyl-2-pyrimidinamine;5-bromo-N-methylpyrimidin-2-amine;2-(Methylamino)-5-bromopyrimidine;(5-BROMOPYRIMIDIN-2-YL)METHYLAMINE;2-Pyrimidinamine, 5-bromo-N-methyl-;Pyrimidine, 5-bromo-2-(methylamino)-;N-(5-Bromopyrimidin-2-yl)-N-methylamine
- CBNumber
- CB7342527
- Molecular Formula
- C5H6BrN3
- Formula Weight
- 188.03
- MOL File
- 31402-54-7.mol
5-BROMO-2-(METHYLAMINO)PYRIMIDINE Property
- Melting point:
- 171-173℃
- Boiling point:
- 283.5±32.0 °C(Predicted)
- Density
- 1.686±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 2.07±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B696950
- Product name
- 5-Bromo-2-(methylamino)pyrimidine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3H31-9-W0
- Product name
- 5-Bromo-2-(methylamino)pyrimidine
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 118854
- Product name
- 5-Bromo-N-methylpyrimidin-2-amine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $46
- Updated
- 2021/12/16
- Product number
- B1746
- Product name
- 5-Bromo-2-(methylamino)pyrimidine
- Purity
- 98%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- OR7851
- Product name
- 5-Bromo-2-(methylamino)pyrimidine
- Packaging
- 1g
- Price
- $66
- Updated
- 2021/12/16
5-BROMO-2-(METHYLAMINO)PYRIMIDINE Chemical Properties,Usage,Production
Synthesis
32779-36-5
74-89-5
31402-54-7
1. 5-Bromo-2-chloropyrimidine (3 g, 15.5 mmol), 40% aqueous methylamine (35 ml) and methanol (20 ml) were added to a reaction flask and mixed well with stirring. 2. The reaction mixture was heated to reflux and kept at that temperature for 3 days. 3. After completion of the reaction, the reaction was cooled to room temperature. 4. The solvent was removed by evaporation using a rotary evaporator under reduced pressure. 5. The residue was extracted by partitioning with dichloromethane and 1M sodium hydroxide. 6. The residue was extracted by partitioning with dichloromethane and 1 M sodium hydroxide solution. 6. The organic layer was separated and dried over anhydrous magnesium sulfate. 7. After filtration to remove the desiccant, the solvent was again evaporated under reduced pressure using a rotary evaporator to give the white solid product 5-bromo-2-methylaminopyrimidine (3.0 g, 100% yield). 8. The product was characterized by 1H-NMR (CDCl3): δ 2.98 (3H, d, J=5.12 Hz), 5.16 (1H, brs), 8.29 (2H, s).
References
[1] Patent: US2010/130492, 2010, A1. Location in patent: Page/Page column 93
[2] Patent: WO2010/12747, 2010, A1. Location in patent: Page/Page column 16-17
[3] Patent: WO2007/84786, 2007, A1. Location in patent: Page/Page column 90
[4] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 1, p. 34 - 38
[5] Patent: WO2012/109423, 2012, A1. Location in patent: Page/Page column 18
5-BROMO-2-(METHYLAMINO)PYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
5-BROMO-2-(METHYLAMINO)PYRIMIDINE Suppliers
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- India
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View Lastest Price from 5-BROMO-2-(METHYLAMINO)PYRIMIDINE manufacturers
- Product
- 5-BROMO-2-(METHYLAMINO)PYRIMIDINE 31402-54-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-13
- Product
- 5-BROMO-2-(METHYLAMINO)PYRIMIDINE 31402-54-7
- Price
- US $2.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2020-01-08