DL-tert-Leucine
- Product Name
- DL-tert-Leucine
- CAS No.
- 33105-81-6
- Chemical Name
- DL-tert-Leucine
- Synonyms
- L-TLE;D-L-Tle;H-TLE-OH;DL-Tle-OH;T-LEUCINE;H-L-TLE-OH;H-DL-TLE-OH;TBU-GLYCINE;L-T-LEUCINE;tert-leucine
- CBNumber
- CB7349551
- Molecular Formula
- C6H13NO2
- Formula Weight
- 131.17
- MOL File
- 33105-81-6.mol
DL-tert-Leucine Property
- Melting point:
- >300 °C (lit.)
- Boiling point:
- 242.49°C (rough estimate)
- Density
- 1.0975 (rough estimate)
- refractive index
- 1.4240 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- H2O: 0.1 g/mL, clear, colorless
- pka
- 2.39±0.12(Predicted)
- form
- Solid
- color
- White to off-white
- Water Solubility
- soluble
- BRN
- 1721823
- InChI
- InChI=1S/C6H13NO2/c1-6(2,3)4(7)5(8)9/h4H,7H2,1-3H3,(H,8,9)
- InChIKey
- NPDBDJFLKKQMCM-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C(C(C)(C)C)N
- CAS DataBase Reference
- 33105-81-6(CAS DataBase Reference)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 29224995
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 332178
- Product name
- DL-tert-Leucine
- Purity
- 98%
- Packaging
- 500mg
- Price
- $131
- Updated
- 2023/06/20
- Product number
- L0439
- Product name
- H-DL-Tle-OH
- Packaging
- 5G
- Price
- $62
- Updated
- 2025/07/31
- Product number
- L0439
- Product name
- H-DL-Tle-OH
- Packaging
- 25G
- Price
- $186
- Updated
- 2025/07/31
- Product number
- 290597
- Product name
- DL-tert-Butylglycine
- Packaging
- 10g
- Price
- $908
- Updated
- 2021/12/16
- Product number
- L330205
- Product name
- Dl-tert-leucine
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
DL-tert-Leucine Chemical Properties,Usage,Production
Chemical Properties
white powder
Uses
peptide synthesis
Definition
ChEBI: Tert-butylglycine is a glycine derivative that is glycine with a tertiary butyl group at position 2. It has a role as a metabolite.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
26782-71-8
33105-81-6
The general procedure for synthesizing DL-tert-leucine from D-tert-leucine is as follows: Example 3A: A 30% ammonium hydroxide solution (50 mL) was added to the autoclave, followed by D-tert-leucine (5 g). The autoclave was sealed and the mixture was heated to 85°C under stirring conditions and maintained at this temperature for 12 hours of reaction. Upon completion of the reaction, the reaction mixture was cooled and the solution was transferred to a rotary evaporator and concentrated under vacuum at 55 °C. The solid residue obtained after concentration was mixed with acetone (20 mL) with stirring, followed by filtration and drying to finally obtain DL-tert-leucine (4.6 g, 92% yield, of which the L-isomer accounted for 42% and the D-isomer for 58%).
References
[1] Patent: US2012/245379, 2012, A1. Location in patent: Page/Page column 3
[2] Patent: EP2502896, 2012, A1. Location in patent: Page/Page column 4-5
DL-tert-Leucine Preparation Products And Raw materials
Raw materials
Preparation Products
DL-tert-Leucine Suppliers
- Tel
- 19135651983 19135651206
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- Country
- China
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- 908
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- 4006356688 18621169109
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- 86-21-61259102
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- China
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- 40228
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- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
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- 30123
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- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
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- Country
- China
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- 44801
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- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
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- 35896
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- Tel
- 21-61263452 13641803416
- Fax
- 86-21-61263399
- ymbetter@glbiochem.com
- Country
- China
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- 9981
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- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
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- 021-50135380
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- China
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- 4009903999 13355009207
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- 0539-6365991
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- China
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- 400-1166-196 18981987031
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- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
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- 11705
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View Lastest Price from DL-tert-Leucine manufacturers
- Product
- DL-tert-Leucine 33105-81-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24