Pinostrobin

ChemicalBook > CAS DataBase List > Pinostrobin

Product Name: Pinostrobin
CAS No.: 480-37-5
Chemical Name: Pinostrobin
Synonyms: Pistrobin;Pinostobin;PINOSTROBIN;Pinostrombin;loteprednol Impurity 18;5-Hydroxy-7-methoxyflavanone;5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one;PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL);5-Hydroxy-7-methoxyflavanone (Pinostrobin);5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin
CBNumber: CB7350900
Molecular Formula: C16H14O4
Formula Weight: 270.28
MOL File: 480-37-5.mol

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Pinostrobin Property

Melting point:: 100°C
Boiling point:: 494.9±45.0 °C(Predicted)
Density: 1.284±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 20 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 12 mg/ml
form: A crystalline solid
pka: 7.40±0.40(Predicted)
LogP: 3.591 (est)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22436
Product name: Pinostrobin
Purity: ≥98%
Packaging: 5mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 22436
Product name: Pinostrobin
Purity: ≥98%
Packaging: 1mg
Price: $38
Updated: 2023/06/20

Cayman Chemical

Product number: 22436
Product name: Pinostrobin
Purity: ≥98%
Packaging: 10mg
Price: $72
Updated: 2024/03/01

TRC

Product number: H947653
Product name: Pinostrombin
Packaging: 10mg
Price: $1400
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP66572
Product name: Pinostrobin
Packaging: 50mg
Price: $150
Updated: 2021/12/16

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Pinostrobin Chemical Properties,Usage,Production

Description

Pinostrobin is a flavonoid with diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It induces quinone reductase (QR) in murine hepatoma cells with a QR doubling concentration of 500 nM. Pinostrobin inhibits TNF-α and IL-1β production in RAW 264.7 macrophages (IC₅₀s = 17.28 and 23.5 μM, respectively) and in LPS-stimulated rats (48.6 and 55% reduction, respectively). Pinostrobin also shows selective cytotoxicity for CCRF-CEM leukemia cells (IC₅₀ = 10.2 μM) in a panel of eight cancer cell lines (IC₅₀s = >30 μM).

Uses

Pinostrombin is a useful research chemical that can be used for chemical fingerprinting, isolating, and characterizing of polyphenol compounds. It can also be used as a potential compound for TMPRSS2 inhibition for Covid-19 therapy.

Definition

ChEBI: A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively.

Pinostrobin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Pinostrobin manufacturers

Career Henan Chemical Co

Product: Pinostrobin 480-37-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2019-12-30

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480-37-5

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Flavanones