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Pinostrobin

Product Name
Pinostrobin
CAS No.
480-37-5
Chemical Name
Pinostrobin
Synonyms
Pistrobin;Pinostobin;PINOSTROBIN;Pinostrombin;loteprednol Impurity 18;5-Hydroxy-7-methoxyflavanone;5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one;PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL);5-Hydroxy-7-methoxyflavanone (Pinostrobin);5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin
CBNumber
CB7350900
Molecular Formula
C16H14O4
Formula Weight
270.28
MOL File
480-37-5.mol
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Pinostrobin Property

Melting point:
100°C
Boiling point:
494.9±45.0 °C(Predicted)
Density 
1.284±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 20 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 12 mg/ml
form 
A crystalline solid
pka
7.40±0.40(Predicted)
LogP
3.591 (est)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22436
Product name
Pinostrobin
Purity
≥98%
Packaging
5mg
Price
$38
Updated
2024/03/01
Cayman Chemical
Product number
22436
Product name
Pinostrobin
Purity
≥98%
Packaging
1mg
Price
$38
Updated
2023/06/20
Cayman Chemical
Product number
22436
Product name
Pinostrobin
Purity
≥98%
Packaging
10mg
Price
$72
Updated
2024/03/01
TRC
Product number
H947653
Product name
Pinostrombin
Packaging
10mg
Price
$1400
Updated
2021/12/16
Biosynth Carbosynth
Product number
FP66572
Product name
Pinostrobin
Packaging
50mg
Price
$150
Updated
2021/12/16
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Pinostrobin Chemical Properties,Usage,Production

Description

Pinostrobin is a flavonoid with diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It induces quinone reductase (QR) in murine hepatoma cells with a QR doubling concentration of 500 nM. Pinostrobin inhibits TNF-α and IL-1β production in RAW 264.7 macrophages (IC50s = 17.28 and 23.5 μM, respectively) and in LPS-stimulated rats (48.6 and 55% reduction, respectively). Pinostrobin also shows selective cytotoxicity for CCRF-CEM leukemia cells (IC50 = 10.2 μM) in a panel of eight cancer cell lines (IC50s = >30 μM).

Uses

Pinostrombin is a useful research chemical that can be used for chemical fingerprinting, isolating, and characterizing of polyphenol compounds. It can also be used as a potential compound for TMPRSS2 inhibition for Covid-19 therapy.

Definition

ChEBI: A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively.

Pinostrobin Preparation Products And Raw materials

Raw materials

Preparation Products

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Pinostrobin Suppliers

China 93 France 1 Germany 2 India 3 Switzerland 1 United Kingdom 4 United States 14 Global 118
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View Lastest Price from Pinostrobin manufacturers

Career Henan Chemical Co
Product
Pinostrobin 480-37-5
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2019-12-30

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  • PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL)
  • 5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one
  • 5-Hydroxy-7-methoxyflavanone
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  • PINOSTROBIN
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  • (2S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (2S)-
  • Pinostrombin
  • 5-Hydroxy-7-methoxyflavanone (Pinostrobin)
  • 5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin
  • loteprednol Impurity 18
  • 480-37-5
  • Food Residue Analysis
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  • Flavanones