Pinostrobin
- Product Name
- Pinostrobin
- CAS No.
- 480-37-5
- Chemical Name
- Pinostrobin
- Synonyms
- Pistrobin;Pinostobin;PINOSTROBIN;Pinostrombin;loteprednol Impurity 18;5-Hydroxy-7-methoxyflavanone;5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one;PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL);5-Hydroxy-7-methoxyflavanone (Pinostrobin);5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin
- CBNumber
- CB7350900
- Molecular Formula
- C16H14O4
- Formula Weight
- 270.28
- MOL File
- 480-37-5.mol
Pinostrobin Property
- Melting point:
- 100°C
- Boiling point:
- 494.9±45.0 °C(Predicted)
- Density
- 1.284±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: 20 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 12 mg/ml
- form
- A crystalline solid
- pka
- 7.40±0.40(Predicted)
- color
- White to yellow
- LogP
- 3.591 (est)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 22436
- Product name
- Pinostrobin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $38
- Updated
- 2024/03/01
- Product number
- 22436
- Product name
- Pinostrobin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $38
- Updated
- 2023/06/20
- Product number
- 22436
- Product name
- Pinostrobin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $72
- Updated
- 2024/03/01
- Product number
- H947653
- Product name
- Pinostrombin
- Packaging
- 10mg
- Price
- $1400
- Updated
- 2021/12/16
- Product number
- FP66572
- Product name
- Pinostrobin
- Packaging
- 50mg
- Price
- $150
- Updated
- 2021/12/16
Pinostrobin Chemical Properties,Usage,Production
Description
Pinostrobin is a flavonoid with diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It induces quinone reductase (QR) in murine hepatoma cells with a QR doubling concentration of 500 nM. Pinostrobin inhibits TNF-α and IL-1β production in RAW 264.7 macrophages (IC50s = 17.28 and 23.5 μM, respectively) and in LPS-stimulated rats (48.6 and 55% reduction, respectively). Pinostrobin also shows selective cytotoxicity for CCRF-CEM leukemia cells (IC50 = 10.2 μM) in a panel of eight cancer cell lines (IC50s = >30 μM).
Uses
Pinostrombin is a useful research chemical that can be used for chemical fingerprinting, isolating, and characterizing of polyphenol compounds. It can also be used as a potential compound for TMPRSS2 inhibition for Covid-19 therapy.
Definition
ChEBI: A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively.
Pinostrobin Preparation Products And Raw materials
Raw materials
Preparation Products
Pinostrobin Suppliers
- Tel
- --
- Fax
- --
- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from Pinostrobin manufacturers
- Product
- Pinostrobin 480-37-5
- Price
- US $1.00-2.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20000KG
- Release date
- 2024-08-09
- Product
- Pinostrobin 480-37-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2019-12-30