3,6-DIMETHOXYPYRIDAZINE

Product Name: 3,6-DIMETHOXYPYRIDAZINE
CAS No.: 4603-59-2
Chemical Name: 3,6-DIMETHOXYPYRIDAZINE
Synonyms: 3,6-DIMETHOXYPYRIDAZINE;Pyridazine, 3,6-diMethoxy-;Pyridazine, 3,6-dimethoxy- (8CI)(9CI)
CBNumber: CB7353406
Molecular Formula: C6H8N2O2
Formula Weight: 140.14
MOL File: 4603-59-2.mol

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3,6-DIMETHOXYPYRIDAZINE Property

Melting point:: 106 °C(Solv: water (7732-18-5))
Boiling point:: 297.4±20.0 °C(Predicted)
Density: 1.131±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 2.48±0.10(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C6H8N2O2/c1-9-5-3-4-6(10-2)8-7-5/h3-4H,1-2H3
InChIKey: HKQOBAGKDBSVEQ-UHFFFAOYSA-N
SMILES: C1(OC)=NN=C(OC)C=C1

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

TRC

Product number: D481023
Product name: 3,6-Dimethoxypyridazine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

ChemScene

Product number: CS-0111913
Product name: 3,6-Dimethoxypyridazine
Purity: 99.51%
Packaging: 1g
Price: $50
Updated: 2021/12/16

Apolloscientific

Product number: OR909190
Product name: 3,6-Dimethoxypyridazine
Purity: 98%
Packaging: 5g
Price: $435
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0310018
Product name: 3,6-DIMETHOXYPYRIDAZINE
Purity: 95.00%
Packaging: 5MG
Price: $495.25
Updated: 2021/12/16

ChemScene

Product number: CS-0111913
Product name: 3,6-Dimethoxypyridazine
Purity: 99.51%
Packaging: 25g
Price: $583
Updated: 2021/12/16

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3,6-DIMETHOXYPYRIDAZINE Chemical Properties,Usage,Production

Uses

3,6-Dimethoxypyridazine is used as a pharmaceutical intermediate in the preparation of sulfonylureas and sulfonylthioureas.

Synthesis

67-56-1

141-30-0

124-41-4

4603-59-2

General procedure for the synthesis of 3,6-dimethoxypyridazine from methanol, 3,6-dichloropyridazine and sodium methanol: 3,6-dichloropyridazine (10.0 g, 67.12 mmol) and sodium methanol (9.79 g, 181.23 mmol) were dissolved in methanol (39 mL) and the reaction was heated at 70 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature, diluted with dichloromethane (200 mL) and subsequently washed with water (100 mL x 2). The organic phase was dried over anhydrous magnesium sulfate and concentrated to dryness under reduced pressure to afford the title compound 3,6-dimethoxypyridazine (9.46 g, 101% yield) as a white solid. The crude product could be directly used in the subsequent reaction without further purification. The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 6.91 (s, 2H), 4.05 (s, 6H). Mass spectrometry (APCI) showed m/z = 182 ([M+H]+). HPLC analysis showed a retention time of 1.19 min.

References

[1] Patent: US2008/318943, 2008, A1. Location in patent: Page/Page column 73

3,6-DIMETHOXYPYRIDAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3,6-DIMETHOXYPYRIDAZINE Suppliers

China 68 India 1 Poland 1 The Netherlands 1 United Kingdom 2 United States 4 Global 77

Yantai Shengkailun Chemical Technology Co., Ltd.

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Energy Chemical

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Shanghai GaoDao Pharmaceutical Co., Ltd.

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View Lastest Price from 3,6-DIMETHOXYPYRIDAZINE manufacturers

Shanghai Rlavie Technology Co ltd

Product: 3,6-Dimethoxypyridazine 4603-59-2
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%minGC
Supply Ability: 500kgs/month
Release date: 2021-11-05

4603-59-2, 3,6-DIMETHOXYPYRIDAZINERelated Search:

3,6-Pyridazinediamine(9CI) 3,4,5-TRICHLOROPYRIDAZINE 3,4-Dihydro-(1H)-benzopyrane 3,4-dichloropyridazine 3,6-Dimethyl Pyridazine 3,5-Dibromopyridazine 3,4,5-Tribromopyridazine 3,4,5,6-TETRACHLOROPYRIDAZINE 3,4,6-Tribromopyridazine 3,6-DIMETHOXYPYRIDAZINE-4-CARBOXYLIC ACID 3-CHLORO-4,5-DIMETHOXYPYRIDAZINE 4-CHLORO-3,5-DIMETHOXYPYRIDAZINE 5-CHLORO-3,4-DIMETHOXYPYRIDAZINE 6-CHLORO-3,4-DIMETHOXYPYRIDAZINE 3,6-Dimethoxypyridazine-4-carboxylic acid methyl ester METHYL 3,6-DIMETHOXYPYRIDAZINE-4-CARBOXYLATE 3,6-DIMETHOXYPYRIDAZINE 1-OXIDE (3,6-Dimethoxypyridazine-4-yl)phenylmethanol

3,6-DIMETHOXYPYRIDAZINE

Pyridazine, 3,6-diMethoxy-

Pyridazine, 3,6-dimethoxy- (8CI)(9CI)

4603-59-2