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S-ETHYL TRIFLUOROTHIOACETATE

Product Name
S-ETHYL TRIFLUOROTHIOACETATE
CAS No.
383-64-2
Chemical Name
S-ETHYL TRIFLUOROTHIOACETATE
Synonyms
ethyltrifluorothioacetate;S-Ethyl Trifluoroacetate;Ethyl trifluorothioacetate;Ethyl trifluorothiolacetate;ETHYL THIOL TRIFLUOROACETATE;S-Ethylthioltrifluoroacetate;S-ETHYL THIOTRIFLUOROACETATE;S-ETHYL TRIFLUOROTHIOACETATE;S-Ethyl trifluoroethanethioate;S-Ethyltrifluorothioacetate97%
CBNumber
CB7354807
Molecular Formula
C4H5F3OS
Formula Weight
158.14
MOL File
383-64-2.mol
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S-ETHYL TRIFLUOROTHIOACETATE Property

Boiling point:
90.5 °C(lit.)
Density 
1.234 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.376(lit.)
Flash point:
39 °F
storage temp. 
Store at RT.
form 
clear liquid
color 
Colorless to Light yellow
BRN 
1761564
CAS DataBase Reference
383-64-2(CAS DataBase Reference)
EPA Substance Registry System
Ethanethioic acid, trifluoro-, S-ethyl ester (383-64-2)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-36/37/38
Safety Statements 
16-26-36
RIDADR 
UN 3272 3/PG 2
WGK Germany 
3
3-9-13-21
Hazard Note 
Flammable/Irritant
HazardClass 
3.1
PackingGroup 
II
HS Code 
2918300090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
177474
Product name
S-Ethyl trifluorothioacetate
Purity
97%
Packaging
10g
Price
$76.7
Updated
2023/06/20
TCI Chemical
Product number
T0872
Product name
S-Ethyl Trifluorothioacetate [Trifluoroacetylating Agent for Peptides Research]
Purity
>98.0%(GC)
Packaging
5mL
Price
$161
Updated
2025/07/31
TRC
Product number
E931300
Product name
S-Ethyl trifluorothioacetate
Packaging
5g
Price
$195
Updated
2021/12/16
Usbiological
Product number
465017
Product name
S-Ethyl Trifluorothioacetate
Packaging
50mg
Price
$312
Updated
2021/12/16
AK Scientific
Product number
7689AH
Product name
S-Ethyl trifluorothioacetate
Packaging
4x25g
Price
$464
Updated
2021/12/16
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S-ETHYL TRIFLUOROTHIOACETATE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to slightly yellow liquid

Uses

S-Ethyl trifluorothioacetate was used to selectively trifluoroacetylate amino groups in proteins.

Synthesis Reference(s)

Journal of the American Chemical Society, 74, p. 4005, 1952 DOI: 10.1021/ja01136a010

Purification Methods

If IR is free of OH bands then fractionally distil it; otherwise dilute the thio-ester with dry Et2O, wash with 5% KOH and H2O, dry over MgSO4 and fractionate it through an efficient column [Hauptschein et al. J Am Chem Soc 74 4005 1952]. [Beilstein 2 IV 567.] Powerful obnoxious odour.

S-ETHYL TRIFLUOROTHIOACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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S-ETHYL TRIFLUOROTHIOACETATE Suppliers

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383-64-2, S-ETHYL TRIFLUOROTHIOACETATERelated Search:


  • ETHYL THIOL TRIFLUOROACETATE
  • TRIFLUOROTHIOACETIC ACID S-ETHYL ESTER
  • Acetic acid, trifluorothio-, S-ethyl ester
  • Ethyl trifluorothioacetate
  • Ethyl trifluorothiolacetate
  • ethyltrifluorothioacetate
  • S-Ethyl trifluoroethanethioate
  • S-Ethylthioltrifluoroacetate
  • Trifluoroethanethioic acid S-ethyl ester
  • trifluoro-ethanethioicacis-ethylester
  • Ethanethioic acid, trifluoro-, S-ethyl ester
  • S-ETHYL THIOTRIFLUOROACETATE
  • S-ETHYL TRIFLUOROTHIOACETATE
  • S-Ethyl trifluorothioacetate 97%
  • S-Ethyltrifluorothioacetate97%
  • S-Ethyl Trifluorothioacetate [Trifluoroacetylating Agent for Peptides Research]
  • S-Ethyl Trifluoroacetate
  • 2,2,2-trifluoroethanethioic acid S-ethyl ester
  • S-ethyl 2,2,2-trifluoroethanethioate
  • <i>S</i>-Ethyl Trifluorothioacetate [Trifluoroacetylating Agent for Peptides Research]
  • Trifluorothioacetic acid S-ethyl
  • S-Ethyl trifluorothioacetate,99%
  • S-Ethyl Trifluorothioacetate [Trifluoroacetylating Agent for Peptides Research]&gt
  • Ethanethioic acid, 2,2,2-trifluoro-, S-ethyl ester
  • <i>S</i>-Ethyl trifluorothioacetate
  • 383-64-2
  • C4H5F3OS
  • CF3COSC2H5
  • Building Blocks
  • Protection & Derivatization Reagents (for Synthesis)
  • Thiol Esters
  • Sulfur Compounds
  • Organic Building Blocks
  • Organics
  • Protection & Derivatization Reagents (for Synthesis)
  • Synthetic Organic Chemistry
  • Thiol Esters
  • Organic Building Blocks
  • Sulfur Compounds