2-BROMO-4,6-DIMETHYLPYRIDINE

Product Name: 2-BROMO-4,6-DIMETHYLPYRIDINE
CAS No.: 4926-26-5
Chemical Name: 2-BROMO-4,6-DIMETHYLPYRIDINE
Synonyms: 2-Bromo-4,6-lutidine;2-Brom-4,6-dimethylpyridin;6-BroMo-2,4-diMethylpyridine;2-BROMO-4,6-DIMETHYLPYRIDINE;2-Bromo-2,4-dimethyl-pyridine;Pyridine, 2-bromo-4,6-dimethyl-;2-bromo-4,6-dimethylpyridine(SALTDATA: FREE);2-BROMO-4,6-DIMETHYLPYRIDINE ISO 9001：2015 REACH;7-chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
CBNumber: CB7361364
Molecular Formula: C7H8BrN
Formula Weight: 186.05
MOL File: 4926-26-5.mol

More

Less

2-BROMO-4,6-DIMETHYLPYRIDINE Property

Boiling point:: 68°C/0.8mmHg(lit.)
Density: 1.415±0.06 g/cm3(Predicted)
refractive index: 1.5510 to 1.5550
storage temp.: Inert atmosphere,Room Temperature
form: clear liquid
pka: 2.17±0.10(Predicted)
color: Colorless to Light yellow
λmax: 268nm(EtOH)(lit.)
InChI: InChI=1S/C7H8BrN/c1-5-3-6(2)9-7(8)4-5/h3-4H,1-2H3
InChIKey: IRTOCXBLUOPRFT-UHFFFAOYSA-N
SMILES: C1(Br)=NC(C)=CC(C)=C1
CAS DataBase Reference: 4926-26-5(CAS DataBase Reference)

More

Less

Safety

HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B5254
Product name: 2-Bromo-4,6-dimethylpyridine
Purity: >98.0%(T)
Packaging: 1g
Price: $128
Updated: 2025/07/31

TCI Chemical

Product number: B5254
Product name: 2-Bromo-4,6-dimethylpyridine
Purity: >98.0%(T)
Packaging: 5g
Price: $384
Updated: 2025/07/31

TRC

Product number: B685865
Product name: 2-Bromo-4,6-dimethylpyridine
Packaging: 10g
Price: $415
Updated: 2021/12/16

TRC

Product number: B685865
Product name: 2-Bromo-4,6-dimethylpyridine
Packaging: 5g
Price: $250
Updated: 2021/12/16

TRC

Product number: B685865
Product name: 2-Bromo-4,6-dimethylpyridine
Packaging: 0.25g
Price: $50
Updated: 2021/12/16

More

Less

2-BROMO-4,6-DIMETHYLPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

2-Bromo-4,6-dimethylpyridine is a reactant in regioselective and diastereoselective syntheses of the natural product CCR5 antagonist anibamine and its three olefin isomers.

Synthesis

5407-87-4

4926-26-5

General procedure for the synthesis of 2-bromo-4,6-dimethylpyridine from 2-amino-4,6-dimethylpyridine: A 48% aqueous hydrobromic acid solution (Aldrich, 65 mL, 1.2 mol, 10 eq.) was cooled to -5 °C and 4,6-dimethylpyridin-2-amine (Aldrich, 15.0 g, 0.12 mol, 1.0 eq.) was added. Bromine (Aldrich, 19.7 mL, 0.38 mol, 3.1 eq.) was added slowly and dropwise with mechanical stirring to the thick white salt mixture formed. The resulting red mixture was treated with aqueous sodium nitrite (32 mL water, Aldrich, 22.1 g, 0.32 mol, 2.6 eq.) for 1 hr below 5 °C. The temperature was maintained below 5°C during the nitrite addition process, followed by a gradual warming to 20°C over 2 hr. The reaction mixture was adjusted to pH 14 with aqueous sodium hydroxide and extracted with methyl tert-butyl ether (MTBE). The organic phase was washed sequentially with water and brine, dried over magnesium sulfate, filtered and concentrated under reduced pressure. The crude product (29 g of red oily material) was purified by fast chromatography (silica gel, 350 g) using 2-7% ethyl acetate-cyclohexane as eluent to give an orange oily product (11.0 g, 48% yield). The product was purified by 1H NMR (DMSO-d6, 300 MHz) δ 7.30 (1H, s), 7.13 (1H, s), 2.39 (3H, s), 2.26 (3H, s); 13C NMR (DMSO-d6, 75 MHz) δ 159.4, 151.3, 140.9, 125.7, 123.4, 23.7, 20.3 ; ESI-MS m/z 186/188 ([M+H]+).

References

[1] Journal of Organic Chemistry, 2011, vol. 76, # 19, p. 7945 - 7952
[2] Helvetica Chimica Acta, 1992, vol. 75, # 5, p. 1578 - 1592
[3] Patent: WO2004/56806, 2004, A1. Location in patent: Page 50
[4] Journal of Medicinal Chemistry, 2014, vol. 57, # 16, p. 7126 - 7135
[5] Patent: EP3124482, 2017, A1. Location in patent: Paragraph 0512; 0513

2-BROMO-4,6-DIMETHYLPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-BROMO-4,6-DIMETHYLPYRIDINE Suppliers

Americas 1 China 107 Europe 2 France 1 Germany 3 India 2 Japan 1 United Kingdom 7 United States 13 Global 137

Jiaxing Yat Tai Biotechnology Co. , Ltd.

Tel: 15824386662
Email: 416719813@qq.com
Country: China
ProdList: 106
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

Tel: 17702719238 18971495150;
Email: sales@sun-shinechem.com
Country: China
ProdList: 1077
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Nan Jing Dirise Chemcial Co.,LTD

Tel: 025-52161033 15312098939
Fax: 025-83254025
Email: sales@njdrschem.com
Country: China
ProdList: 583
Advantage: 64

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

More

Less

View Lastest Price from 2-BROMO-4,6-DIMETHYLPYRIDINE manufacturers

Dideu Industries Group Limited

Product: 2-BROMO-4,6-DIMETHYLPYRIDINE 4926-26-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-26

Career Henan Chemical Co

Product: 2-BROMO-4,6-DIMETHYLPYRIDINE 4926-26-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-03

4926-26-5, 2-BROMO-4,6-DIMETHYLPYRIDINERelated Search:

2-BROMO-6-METHYL-4-TRIFLUOROMETHYLPYRIDINE 6-BROMO-2,4-DIMETHYLPYRIDIN-3-YLBORONIC ACID 2-BROMO-4,6-DIMETHYLPYRIDINE 3-AMINO-2-BROMO-4,6-DIMETHYLPYRIDINE,5-Amino-2-bromo-4,6-dimethylpyridine 4-Chlorophenethylamine 2-AMINO-5-BROMO-3,4-DIMETHYLPYRIDINE,2-AMINO-5-BROMO-3,4-DIMETHYLPYRIDINE 97% 5-Bromo-2-(dimethylamino)pyridine 2-AMINO-3-BROMO-5,6-DIMETHYLPYRIDINE 4-Bromo-2,6-dimethylpyridine 3-Bromo-2,6-dimethylpyridine 98%,3-BROMO-2,6-DIMETHYLPYRIDINE 3-Bromo-2,5-dimethylpyridine 3-BROMO-2,4-DIMETHYLPYRIDINE 6-BROMO-[2,2'-BIPYRIDINE]-4-CARBOXYLIC ACID 6-BROMO-4,4'-DIMETHYL-2,2'-BIPYRIDINE METHYL 2-BROMO-6-METHYLISONICOTINATE 3-BROMO-4,5-DIMETHYLPYRIDINE 5-BROMO-2,3-DIMETHYLPYRIDINE 6-Bromo-3-iodo-2,4-dimethylpyridine

2-Bromo-2,4-dimethyl-pyridine

2-BROMO-4,6-DIMETHYLPYRIDINE

7-chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid

6-BroMo-2,4-diMethylpyridine

2-bromo-4,6-dimethylpyridine(SALTDATA: FREE)

Pyridine, 2-bromo-4,6-dimethyl-

2-Bromo-4,6-lutidine

2-BROMO-4,6-DIMETHYLPYRIDINE ISO 9001：2015 REACH

2-Brom-4,6-dimethylpyridin

4926-26-5

Heterocyclic Compounds

Pyridines

Boronic Acid

Heterocycle-Pyridine series

Pyridine

Pyridine Series