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Nadph tetrasodium salt

Product Name
Nadph tetrasodium salt
CAS No.
2646-71-1
Chemical Name
Nadph tetrasodium salt
Synonyms
β-NADPH;NADPH (sodium salt);TPNH;TPNH,NA4;BETA-NADPH TETRASODIUM SALT;TRIPHOSPHOPYRIDINE NUCLEOTIDE (REDUCED) SODIUM SALT;TRIPHOSPHOPYRIDINE NUCLEOTIDE REDUCED TETRASODIUM SALT;TRIPHOSPHOPYRIDINE NUCLEOTIDE, REDUCED FORM TETRASODIUM SALT;BETA-NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE, REDUCED, 4NA;BETA-TRIPHOSPHOPYRIDINE NUCLEOTIDE TETRASODIUM SALT,REDUCED FORM
CBNumber
CB7365362
Molecular Formula
C21H31N7NaO17P3
Formula Weight
769.42
MOL File
2646-71-1.mol
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Nadph tetrasodium salt Property

Melting point:
>250°C (dec.)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
10 mM NaOH: soluble50mg/mL, clear
form 
Powder
color 
White to Off-white
Water Solubility 
Soluble in water (50 mg/ml).
Sensitive 
Light Sensitive
λmax
260 and 340 nm
Merck 
14,6348
InChIKey
ZQJHSLJFGRIJQN-LRANKJFRNA-N
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Safety

Hazard Codes 
Xi,F
Risk Statements 
36/37/38-11
Safety Statements 
26-36/37
WGK Germany 
3
3-10-23
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
NADPH-RO
Product name
NADPH
Purity
Tetrasodiumsalt
Packaging
100mg
Price
$267
Updated
2025/07/31
Sigma-Aldrich
Product number
NADPH-RO
Product name
NADPH
Purity
Tetrasodiumsalt
Packaging
500mg
Price
$1050
Updated
2025/07/31
Sigma-Aldrich
Product number
NADPH-RO
Product name
NADPH
Purity
Tetrasodiumsalt
Packaging
1g
Price
$1780
Updated
2025/07/31
Sigma-Aldrich
Product number
N9910
Product name
β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt
Purity
vial of 0.30-0.36?mg
Packaging
15vials
Price
$271
Updated
2025/07/31
Sigma-Aldrich
Product number
N9660
Product name
β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt
Purity
vial of 5?mg
Packaging
15vials
Price
$630
Updated
2025/07/31
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Nadph tetrasodium salt Chemical Properties,Usage,Production

Description

NADPH is the reduced form of the coenzyme NADP+; used in anabolic reactions such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.
NADPH, Tetrasodium Salt is a A ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes. It is generated by reduction of the electron acceptor NADP+. The following biological pathways involve NADPH: formation of carbohydrate from CO2 during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin.

Chemical Properties

off-white to light yellow powder

Uses

NADPH tetra sodium salt is used as an ubiquitous cofactor and biological reducing agent. β-NADPH is a coenzyme found in all living cells and is involved in redox reactions carrying electrons from one reaction to another. It is used as an electron donor, cofactor for many redox enzymes including nitric oxide synthetase.

Mechanism of action

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Reactions

Nadph tetrasodium salt is one of the biologically active forms of nicotinic acid. Differs from NAD by an additional phosphate group at the 2’position of the adenosine moiety. Serves as a coenzyme of hydrogenases and dehydroge nases. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions.

Application

NADPH is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reactions. In plants, NADPH is produced by ferredoxin-NADP+ reductase in the last step of the electron chain during photosynthesis. In animals is it predominantly produced by the pentose phosphate pathway, but is also generated by key mitochondrial enzymes. NADPH provides the reducing equivalents for biosynthetic reactions and the oxidation-reduction involved in protecting against the toxicity of reactive oxygen species.It is also used for the synthesis of lipids and cholesterol and during the process of fatty acid chain elongation.

General Description

A ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes. It is generated by reduction of the electron acceptor NADP+. The following biological pathways involve NADPH: formation of carbohydrate from CO2 during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin.

Biological Activity

NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Biochem/physiol Actions

NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.

Source

Nadph tetrasodium salt is a form of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) where the sodium salt enhances its solubility, facilitating its use in various biochemical assays.

storage

-20°C

Purification Methods

Purification is mostly similar to that of NADH above. [Beilstein 26 III/IV 3671.]

Nadph tetrasodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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Nadph tetrasodium salt Suppliers

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View Lastest Price from Nadph tetrasodium salt manufacturers

WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)
Product
NADPH, Tetrasodium Salt 2646-71-1
Price
US $0.00-0.00/g
Min. Order
10g
Purity
99%
Supply Ability
100KG
Release date
2025-08-19
WUHAN FORTUNA CHEMICAL CO., LTD
Product
NADPH, Tetrasodium Salt 2646-71-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
1000kg
Release date
2023-01-13
Chongqing Soarwin Technology Co., Ltd
Product
BETA-NADPH TETRASODIUM SALT 2646-71-1
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.99%
Supply Ability
20 tons
Release date
2025-04-11

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