Hydroxybupropione

Product Name: Hydroxybupropione
CAS No.: 92264-81-8
Chemical Name: Hydroxybupropione
Synonyms: HYDROXYBUPROPION;HYDROXYBUPROPIONE;Bupropion Impurity 7;Bupropion Impurity 24;Hydroxymethyl Bupropion;(±)-Hydroxybupropion solution;Hydroxybupropione/Bupropion morpholinol;2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE;1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino;1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone
CBNumber: CB7367225
Molecular Formula: C13H18ClNO2
Formula Weight: 255.74
MOL File: 92264-81-8.mol

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Hydroxybupropione Property

Melting point:: 121-123°C
Boiling point:: 393.9±32.0 °C(Predicted)
Density: 1.150±0.06 g/cm3(Predicted)
Flash point:: 2℃
storage temp.: -20°C
solubility: Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
form: Solid
pka: 15.43±0.10(Predicted)
color: White to Pale Yellow

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Safety

Hazard Codes: F,Xn
Risk Statements: 11-20/21/22-36
Safety Statements: 16-36/37
RIDADR: UN 1648 3 / PGII
WGK Germany: 2
HS Code: 3822900000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H-066
Product name: (±)-Hydroxybupropion solution
Purity: 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $57.1
Updated: 2024/03/01

Usbiological

Product number: H9038-15
Product name: Hydroxybupropion
Packaging: 10mg
Price: $439
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: MTB0000752
Product name: HYDROXYBUPROPIONE
Purity: 95.00%
Packaging: 5MG
Price: $497.02
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 33224
Product name: Hydroxybupropion
Purity: min.95%
Packaging: 50mg
Price: $990
Updated: 2021/12/16

ChemScene

Product number: CS-0019871
Product name: Hydroxybupropion
Purity: 99.91%
Packaging: 5mg
Price: $250
Updated: 2021/12/16

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Hydroxybupropione Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3?chlorophenyl)-355-trimethylmorpholine). See US Pat. # 6342496

Definition

ChEBI: Hydroxybupropion is an aromatic ketone.

General Description

(±)-Hydroxybupropion is a primary metabolite of bupropion. Bupropion is a pharmaceutical used as an antidepressant and a smoking cessation drug sold under the trade names Wellbutrin^? and Zyban^?. This Certified Spiking Solution^? is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research.

Hydroxybupropione Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxybupropione Suppliers

Canada 1 China 49 France 1 Germany 1 India 4 United States 17 Global 73

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 335
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 0086-15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7850
Advantage: 55

Artis Biotech Co. Ltd.

Tel: 0575-18780151478 18582380095
Fax: 0575-89298961
Email: sales@artisbio.com
Country: China
ProdList: 2966
Advantage: 58

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-28967200 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9578
Advantage: 60

Chengdu Novel Biomedical Co., Ltd.

Tel: 028-85255396 18302801538
Fax: 028-85255396
Email: cdnovell@163.com
Country: China
ProdList: 2314
Advantage: 58

92264-81-8, HydroxybupropioneRelated Search:

DIMETHYLAMINOPYRIDINE, POLYMER-BOUND Chlorodimethylphenylsilane Glycolic acid Hydroxy silicone oil HYDROXYAPATITE TYPE I 3,4'-DIAMINODIPHENYLMETHANE N,N-Dimethyl-1,4-phenylenediamine Betaine ALTRENOGEST 4-Hydroxybenzoic acid Silicone oil (high temperature) CHLOROPHOSPHONAZO III Bupropion Glycine Bupropion hydrochloride Camptothecin Series--10-hydroxycamptothecin TRIS EDTA ACETATE BUFFER, 10X, DNASE, RNASE AND PROTEASE FREE, PH 8.3, FOR MOLECULAR BIOLOGY Bupropion

HYDROXYBUPROPION

HYDROXYBUPROPIONE

1-(3-CHLOROOPHENYL)-2-[(2-HYDROXY-1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE

2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE

1-(3-Chloroophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone,2-Hydroxy-2-(3chlorophenyl)-3,5,5-trimethylmorpholine

1-(3-Chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one

1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone

(±)-Hydroxybupropion solution

Bupropion Impurity 7

Bupropion Impurity 24

1-Propanone, 1-(3-chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-

1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino

Hydroxymethyl Bupropion

Hydroxybupropione/Bupropion morpholinol

92264-81-8

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

Bupropion