ChemicalBook > CAS DataBase List > 2-Fluoro-6-nitrophenol

2-Fluoro-6-nitrophenol

Product Name
2-Fluoro-6-nitrophenol
CAS No.
1526-17-6
Chemical Name
2-Fluoro-6-nitrophenol
Synonyms
2-Fluoro-6-nitrophen;2-Fluor-6-nitro-phenol;6-FLUORO-2-NITROPHENOL;2-FLUORO-6-NITROPHENOL;2-NITRO-6-FLUORO PHENOL;fluoro-2 nitro-6 phenol;Phenol,2-fluoro-6-nitro-;Fluoro-6-nitrophenol, 2-;2-Fluoro-6-nitrophenol98%;2-Fluoro-6-nitrophenol>
CBNumber
CB7371453
Molecular Formula
C6H4FNO3
Formula Weight
157.1
MOL File
1526-17-6.mol
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2-Fluoro-6-nitrophenol Property

Melting point:
92-94°C
Boiling point:
201.5±20.0 °C(Predicted)
Density 
1.511±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
5.67±0.24(Predicted)
color 
Light yellow to Yellow to Orange
BRN 
1870307
InChI
InChI=1S/C6H4FNO3/c7-4-2-1-3-5(6(4)9)8(10)11/h1-3,9H
InChIKey
HIGRXCJEFUYRNW-UHFFFAOYSA-N
SMILES
C1(O)=C([N+]([O-])=O)C=CC=C1F
CAS DataBase Reference
1526-17-6(CAS DataBase Reference)
EPA Substance Registry System
2-Fluoro-6-nitrophenol (1526-17-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37/39-36/37
RIDADR 
2811
HazardClass 
IRRITANT
PackingGroup 
III
HS Code 
29089990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
F0623
Product name
2-Fluoro-6-nitrophenol
Purity
>98.0%(GC)
Packaging
1g
Price
$32
Updated
2025/07/31
TCI Chemical
Product number
F0623
Product name
2-Fluoro-6-nitrophenol
Purity
>98.0%(GC)
Packaging
5g
Price
$95
Updated
2025/07/31
TRC
Product number
F594845
Product name
2-Fluoro-6-nitrophenol
Packaging
25g
Price
$470
Updated
2021/12/16
TRC
Product number
F594845
Product name
2-Fluoro-6-nitrophenol
Packaging
10g
Price
$230
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0019920
Product name
2-FLUORO-6-NITROPHENOL
Purity
95.00%
Packaging
100G
Price
$2609.15
Updated
2021/12/16
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2-Fluoro-6-nitrophenol Chemical Properties,Usage,Production

Uses

2-Fluoro-6-nitrophenol has antifungal- and high plant-growth-regulating activity.

Synthesis

367-12-4

7440-44-0

1526-17-6

403-19-0

A. Synthesis of 2-fluoro-4-nitrophenol To a stirred dichloromethane solution of 2-fluorophenol (32.3 g, 0.288 mol) was slowly added 90% nitric acid (1 g, 0.31 mol HNO3) in an ice-salt bath cooled to -10°C. The addition process was controlled to be completed in 1 hour. During the reaction, the temperature was maintained at about -5 °C. After the addition was completed, stirring was continued at 0°C for 1 hour. At the end of the reaction, the precipitate was collected by filtration and washed several times with cold dichloromethane. Analysis by GC and thin layer chromatography (silica gel, 7:3 hexane-acetone) showed that the product was mainly a single compound and that the by-products produced in the reaction were of low polarity and volatility. The solid was dissolved in ether, washed with water, dried (MgSO4) and the solvent evaporated. The resulting solid was recrystallized with methylcyclohexane to give 13 g of a pale yellow solid with a melting point of 119°-121°C. NMR (CDCl3) analysis confirmed the product as 2-fluoro-4-nitrophenol. The dichloromethane mother liquor was treated, washed with water, dried (MgSO4) and the solvent evaporated. The solid obtained was ground with boiling hexane (3 x 150 ml) to effectively remove the least polar and highly volatile reaction by-products. The hexane solution was treated with activated charcoal, filtered and concentrated to about 300 ml and cooled to give 13.5 g (30% yield) of the by-product 2-fluoro-6-nitrophenol as a yellow solid with a melting point of 70°-86 °C.

References

[1] Patent: US4750931, 1988, A
[2] Patent: EP142328, 1991, B1

2-Fluoro-6-nitrophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Fluoro-6-nitrophenol manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-Fluoro-6-nitrophenol 1526-17-6
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22
Hebei Senko Biotechnology Co., Ltd.
Product
2-Fluoro-6-nitrophenol 1526-17-6
Price
US $10.00/Kg/Bag
Min. Order
1KG
Purity
99%
Supply Ability
10Tons
Release date
2021-07-20
Career Henan Chemical Co
Product
2-Fluoro-6-nitrophenol 1526-17-6
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-08

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