2-Fluoro-6-nitrobenzoic acid
- Product Name
- 2-Fluoro-6-nitrobenzoic acid
- CAS No.
- 385-02-4
- Chemical Name
- 2-Fluoro-6-nitrobenzoic acid
- Synonyms
- uoro-6-nitrobenzoic acid;2-Fluoro-6-nitrobenzoicaci;6-Fluoro-2-nitrobenzoic Acid;2-Fluoro-6-nitrobenzotc acid;2-FLUORO-6-NITROBENZOIC ACID;Benzoicacid, 2-fluoro-6-nitro-;2-Carboxy-3-fluoronitrobenzene;2-Flouride-6-Nitro Benzoic Acids;2-Fluoro-6-nitrobenzoic acid, 97%;2-Fluoro-6-nitrobenzoic acid, 98%,
- CBNumber
- CB4491402
- Molecular Formula
- C7H4FNO4
- Formula Weight
- 185.11
- MOL File
- 385-02-4.mol
2-Fluoro-6-nitrobenzoic acid Property
- Melting point:
- 150 °C
- Boiling point:
- 334.7±27.0 °C(Predicted)
- Density
- 1.568±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 1.50±0.30(Predicted)
- form
- Solid
- color
- White to Light yellow to Light orange
- CAS DataBase Reference
- 385-02-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 29163900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F1107
- Product name
- 6-Fluoro-2-nitrobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $86
- Updated
- 2025/07/31
- Product number
- F595048
- Product name
- 2-Fluoro-6-nitrobenzoicacid
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- PC5538
- Product name
- 2-Fluoro-6-nitrobenzoicacid
- Purity
- 97%
- Packaging
- 5g
- Price
- $16
- Updated
- 2021/12/16
- Product number
- 012622
- Product name
- 2-Fluoro-6-nitrobenzoic acid
- Packaging
- 5g
- Price
- $19
- Updated
- 2021/12/16
- Product number
- 4654-3-90
- Product name
- 2-Fluoro-6-nitrobenzoic acid
- Purity
- 98%
- Packaging
- 5G
- Price
- $20
- Updated
- 2021/12/16
2-Fluoro-6-nitrobenzoic acid Chemical Properties,Usage,Production
Chemical Properties
light yellow powder
Uses
2-Fluoro-6-nitrobenzoic acid is used as an intermediate in the synthesis of certain drugs, pesticides or advanced materials.
Synthesis
769-10-8
385-02-4
A. Synthesis of 2-fluoro-6-nitrobenzoic acid. Under stirring, 2-fluoro-6-nitrotoluene (exact amount not provided) was added to a suspension of potassium permanganate (102 g, 0.65 mol) in water (1.4 L). The reaction mixture was heated to reflux for 4 h, subsequently cooled to room temperature, filtered and washed with diethyl ether. The aqueous phase was acidified to pH 2 with concentrated hydrochloric acid and then extracted with ethyl acetate. The organic phase was washed with brine, dried over magnesium sulfate, filtered, and concentrated under vacuum to give 11.81 g (40% yield) of 2-fluoro-6-nitrobenzoic acid. The product was characterized by 1H NMR and IS-MS (m/e 184.0 [M-1]). Elemental analysis (C7H4FNO4) Calculated values: C, 45.42; H, 2.18; N, 7.57; Measured values: C, 45.22; H, 2.29; N, 7.27.
References
[1] Chemische Berichte, 1896, vol. 29, p. 841
[2] Journal of Medicinal Chemistry, 1994, vol. 37, # 6, p. 758 - 768
[3] Israel Journal of Chemistry, 1964, vol. 2, p. 25 - 28
[4] Patent: US6635657, 2003, B1
[5] Patent: US4316839, 1982, A
2-Fluoro-6-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Fluoro-6-nitrobenzoic acid manufacturers
- Product
- 2-Fluoro-6-nitrobenzoic acid 385-02-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 2-Fluoro-6-nitrobenzoic acid 385-02-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 2-Fluoro-6-nitrobenzoic acid 385-02-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-20