Ethyl 4-fluoro-3-nitrobenzoate

Product Name: Ethyl 4-fluoro-3-nitrobenzoate
CAS No.: 367-80-6
Chemical Name: Ethyl 4-fluoro-3-nitrobenzoate
Synonyms: RARECHEM AL BI 0858;4-fluoro-3-nitro-benzoate;Ethyl 3-Nitro-4-Fluorobenzoate;ETHYL 4-FLUORO-3-NITROBENZOATE;Ethyl 4-fluoro-3-nitrobenzoate-2;5-(Ethoxycarbonyl)-2-fluoronitrobenzene;4-FLUORO-3-NITROBENZOIC ACID ETHYL ESTER;Benzoic acid, 4-fluoro-3-nitro-, ethyl ester
CBNumber: CB6229357
Molecular Formula: C9H8FNO4
Formula Weight: 213.16
MOL File: 367-80-6.mol

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Ethyl 4-fluoro-3-nitrobenzoate Property

Melting point:: 45.3 °C
Boiling point:: 312.3±22.0 °C(Predicted)
Density: 1.333±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: crystalline powder
color: Pale creamy lemon
CAS DataBase Reference: 367-80-6(CAS DataBase Reference)

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Safety

HS Code: 2918300090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: E918238
Product name: Ethyl4-fluoro-3-nitrobenzoate
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: E918238
Product name: Ethyl4-fluoro-3-nitrobenzoate
Packaging: 1g
Price: $75
Updated: 2021/12/16

Apolloscientific

Product number: PC1485
Product name: Ethyl4-fluoro-3-nitrobenzoate
Packaging: 25g
Price: $56
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4654-3-X4
Product name: Ethyl 4-fluoro-3-nitrobenzoate
Packaging: 25g
Price: $61
Updated: 2021/12/16

Apolloscientific

Product number: PC1485
Product name: Ethyl4-fluoro-3-nitrobenzoate
Packaging: 5g
Price: $22
Updated: 2021/12/16

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Ethyl 4-fluoro-3-nitrobenzoate Chemical Properties,Usage,Production

Synthesis

64-17-5

453-71-4

367-80-6

Step 1: 5.00 g (27.0 mmol) of 4-fluoro-3-nitrobenzoic acid was dissolved in 50 mL of saturated ethanolic hydrochloric acid solution (1.25 M) and the reaction was refluxed for 15 hours. After completion of the reaction, the reaction mixture was evaporated using a rotary evaporator. Purification by fast column chromatography [silica gel, eluent petroleum ether/ethyl acetate (4:1)] afforded 5.48 g (25.7 mmol, 95%) of ethyl 4-fluoro-3-nitrobenzoate as a colorless solid. Thin layer chromatography (TLC) Rf = 0.48 [silica gel, petroleum ether/ethyl acetate (4:1)]. Mass Spectrometry (ESI) m/z: [M + H]+ calculated value of 214.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 7, p. 1859 - 1863
[2] Patent: US2007/112033, 2007, A1. Location in patent: Page/Page column 17-18
[3] Patent: US2013/79306, 2013, A1. Location in patent: Paragraph 0226; 0227; 0228; 0229
[4] Journal of Medicinal Chemistry, 2012, vol. 55, # 16, p. 7262 - 7272
[5] Journal of Medicinal Chemistry, 2018, vol. 61, # 4, p. 1646 - 1663

Ethyl 4-fluoro-3-nitrobenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 4-fluoro-3-nitrobenzoate Suppliers

China 99 Europe 2 Germany 2 India 3 United Kingdom 6 United States 20 Global 132

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View Lastest Price from Ethyl 4-fluoro-3-nitrobenzoate manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Ethyl 4-fluoro-3-nitrobenzoate 367-80-6
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-25

Career Henan Chemical Co

Product: Ethyl 4-fluoro-3-nitrobenzoate 367-80-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-02

367-80-6, Ethyl 4-fluoro-3-nitrobenzoateRelated Search:

Ethanol Ethyl acrylate Ethyl 2-chloromethylbenzoate Ethylbenzene Ethylparaben CHLOROETHANE 4-Fluoronitrobenzene Urethane Ethyl cellulose Ethyl benzoate 1-Fluoro-2-nitrobenzene Ethyl formate Ethyl acetate Fluorine 2-AMINO-6-FLUORO-3-NITROBENZOIC ACID ETHYL ESTER 4-Fluoro-3-nitrobenzoic acid Diethyl ether Ethyl chloroformate

ETHYL 4-FLUORO-3-NITROBENZOATE

4-FLUORO-3-NITROBENZOIC ACID ETHYL ESTER

RARECHEM AL BI 0858

Ethyl 4-fluoro-3-nitrobenzoate-2

Benzoic acid, 4-fluoro-3-nitro-, ethyl ester

4-fluoro-3-nitro-benzoate

5-(Ethoxycarbonyl)-2-fluoronitrobenzene

Ethyl 3-Nitro-4-Fluorobenzoate

367-80-6

376-80-6

C9H8NO4F

C9H8FNO4

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