ChemicalBook > CAS DataBase List > 4-PHENYLPIPERIDINE HYDROCHLORIDE

4-PHENYLPIPERIDINE HYDROCHLORIDE

Product Name
4-PHENYLPIPERIDINE HYDROCHLORIDE
CAS No.
10272-49-8
Chemical Name
4-PHENYLPIPERIDINE HYDROCHLORIDE
Synonyms
4-Phenylpiperdine HCL;4-phenylpiperidinium chloride;4-Phenylpiperdine hydrochloride;4-PHENYLPIPERIDINE HYDROCHLORIDE;Piperidine, 4-phenyl-,hydrochloride (1:1);1,2,3,6-Tetrahydro-4-phenylpiperidine hydrochloride
CBNumber
CB7376302
Molecular Formula
C11H16ClN
Formula Weight
197.7
MOL File
10272-49-8.mol
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4-PHENYLPIPERIDINE HYDROCHLORIDE Property

Melting point:
164-165℃
storage temp. 
Inert atmosphere,Room Temperature
Appearance
White to off-white Solid
InChI
InChI=1S/C11H15N.ClH/c1-2-4-10(5-3-1)11-6-8-12-9-7-11;/h1-5,11-12H,6-9H2;1H
InChIKey
UPZJLQCUYUTZIE-UHFFFAOYSA-N
SMILES
C1(C=CC=CC=1)C1CCNCC1.Cl
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P336355
Product name
4-Phenylpiperidinehydrochloride
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
P336355
Product name
4-Phenylpiperidinehydrochloride
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
P336355
Product name
4-Phenylpiperidinehydrochloride
Packaging
500mg
Price
$90
Updated
2021/12/16
AK Scientific
Product number
Z3814
Product name
4-Phenylpiperidinehydrochloride
Packaging
5g
Price
$154
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0013309
Product name
4-PHENYL-PIPERIDINE HYDROCHLORIDE
Purity
95.00%
Packaging
1G
Price
$424
Updated
2021/12/16
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4-PHENYLPIPERIDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

mp 154-158°C

Synthesis

43064-12-6

10272-49-8

The general procedure for the synthesis of 4-phenylpiperidine hydrochloride from 4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride was as follows: 10% palladium carbon (100 mg) was added to a stirred solution of 4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (300 mg, 1.53 mmol) in methanol (10 mL) under argon protection. Subsequently, the reaction mixture was flushed with hydrogen three times and the reaction was stirred under hydrogen atmosphere (balloon) for 4 hours. The reaction progress was monitored by LCMS. After completion of the reaction, the reaction mixture was filtered through a short diatomaceous earth pad and washed with methanol (5 mL). The filtrate was concentrated under reduced pressure and the residue was washed with anhydrous ether (2 x 5 mL) to give the final 4-phenylpiperidine hydrochloride (300 mg, 99%) as an off-white hygroscopic solid. m/z 162.3 [M+H]+ by LCMS.

References

[1] Patent: US2003/171370, 2003, A1
[2] Patent: WO2018/125961, 2018, A1. Location in patent: Page/Page column 42; 43
[3] Patent: US2004/92524, 2004, A1. Location in patent: Page/Page column 38
[4] Patent: US6355642, 2002, B1. Location in patent: Page column 14
[5] Patent: EP1020434, 2000, A1

4-PHENYLPIPERIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-PHENYLPIPERIDINE HYDROCHLORIDE Suppliers

China 63 Germany 1 India 3 South Korea 1 Ukraine 1 United Kingdom 2 United States 15 Global 86
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View Lastest Price from 4-PHENYLPIPERIDINE HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
4-PHENYLPIPERIDINE HYDROCHLORIDE 10272-49-8
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2018-08-04

10272-49-8, 4-PHENYLPIPERIDINE HYDROCHLORIDERelated Search:

MEPERIDINE HYDROCHLORIDE NALORPHINE HYDROCHLORIDE Loperamide hydrochloride 4-CYANO-4-PHENYLPIPERIDINE HYDROCHLORIDE 99%,4-CYANO-4-PHENYLPIPERIDINE HYDROCHLORIDE Haloperidol DIPHENOXYLATE HYDROCHLORIDE 4-(4-Chlorophenyl)piperidin-4-ol 1-Benzyl-4-cyano-4-phenylpiperidine hydrochloride,1-Benzyl-4-cyano-4-phenylpiperidine hydrochloride 99% 4-ACETYL-4-PHENYLPIPERIDINE HYDROCHLORIDE,4-ACETYL-4-PHENYLPIPERIDINE HYDROCHLORIDE 99% 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol 4-[3-(TRIFLUOROMETHYL)PHENYL]-4-PIPERIDINOL HYDROCHLORIDE Naloxone hydrochloride 3-PHENYLPIPERIDINE HYDROCHLORIDE 1-N-Benzyl-4-Cyano-4-Phenylpiperidine Hydrochloride 1,1-Benzyl-4-cyano-4-phenylpiperidine hydrochloride ,1-N-BENZYL-4-CYANO-4-PHENYLPIPERIDINE HYDROCHLORIDE TRIFLUPERIDOL HCL 4-[4-(4-CHLOROPHENYL)-4HYDROXY-1-PIPERIDINYL]-1-(4-CHLOROPHENYL)-1-BUTANONE (+/-)-VESAMICOL HYDROCHLORIDE 4-Carboethoxy-4-phenylpiperidine hydrochloride

  • 4-PHENYLPIPERIDINE HYDROCHLORIDE
  • 1,2,3,6-Tetrahydro-4-phenylpiperidine hydrochloride
  • 4-phenylpiperidinium chloride
  • 4-Phenylpiperdine HCL
  • 4-Phenylpiperdine hydrochloride
  • Piperidine, 4-phenyl-,hydrochloride (1:1)
  • 10272-49-8
  • 0272-49-8
  • C11H14NHCl
  • john's