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METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE

Product Name
METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE
CAS No.
20699-85-8
Chemical Name
METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE
Synonyms
ASISCHEM D48912;ethyl thieno[3,2-f]quinoline-2-carboxylate;ethyl 5-aMinobenzo[b]thiophene-2-carboxylate;METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE;methyl 5-aminobenzo[b]thiophene-2-carboxylate;5-Aminothionaphthene-2-carboxylic acid methyl ester;5-AMINO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER;Benzo[b]thiophene-2-carboxylic acid, 5-amino-, methyl ester
CBNumber
CB7389371
Molecular Formula
C10H9NO2S
Formula Weight
207.25
MOL File
20699-85-8.mol
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METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE Property

Melting point:
178-179 ºC
Boiling point:
382.8±22.0 °C(Predicted)
Density 
1.352±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
3.52±0.10(Predicted)
Appearance
Light yellow to yellow Solid
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
22-26-36/37/39
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
M286670
Product name
Methyl5-Aminobenzo[b]thiophene-2-carboxylate
Packaging
100mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
W4346
Product name
Methyl5-aminobenzo[b]thiophene-2-carboxylate
Packaging
1g
Price
$130
Updated
2021/12/16
Matrix Scientific
Product number
118889
Product name
Methyl 5-aminobenzo[b]thiophene-2-carboxylate
Purity
95+%
Packaging
1g
Price
$216
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0030724
Product name
METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE
Purity
95.00%
Packaging
250MG
Price
$629.42
Updated
2021/12/16
Matrix Scientific
Product number
118889
Product name
Methyl 5-aminobenzo[b]thiophene-2-carboxylate
Purity
95+%
Packaging
5g
Price
$720
Updated
2021/12/16
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METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE Chemical Properties,Usage,Production

Definition

ChEBI: Methyl 5-amino-1-benzothiophene-2-carboxylate is a member of 1-benzothiophenes.

Synthesis

20699-86-9

20699-85-8

General procedure for the synthesis of methyl 5-aminobenzothiophene-2-carboxylate from methyl 5-nitrobenzo[b]thiophene-2-carboxylate: to a reaction flask was added methyl 5-nitrobenzo[b]thiophene-2-carboxylate (1 g, 0.004 mol), concentrated nitric acid (20 mL, 0.24 mol) and SnCl2-2H2O (4.85 g, 0.017 mol). The reaction mixture was stirred at 80 °C for 1 h and subsequently cooled to room temperature. The pH of the reaction mixture was adjusted with 10% aqueous sodium hydroxide solution to 9~11. The resulting suspension was filtered and the solid residue was washed with water and methanol sequentially to afford the target product, methyl 5-aminobenzothiophene-2-carboxylate, as a yellow solid in quantitative yield.

References

[1] Patent: WO2006/101454, 2006, A1. Location in patent: Page/Page column 45
[2] Bioorganic and Medicinal Chemistry, 2002, vol. 10, # 5, p. 1611 - 1618
[3] Journal of the American Chemical Society, 2000, vol. 122, # 27, p. 6382 - 6394
[4] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 9, p. 963 - 967
[5] Patent: WO2005/42513, 2005, A1. Location in patent: Page/Page column 57-58

METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE Suppliers

Belgium 1 China 61 Germany 2 India 1 United States 11 Global 76
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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PharmaBlock Sciences (Nanjing),Inc.
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025-86918202 4000255188
Fax
86-025-86918232
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sales@pharmablock.com
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China
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5000
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
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86-21-61259102
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market03@meryer.com
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China
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40228
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Adamas Reagent, Ltd.
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400-6009262 16621234537
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021-64823266
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chenyj@titansci.com
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China
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Shanghai Longsheng chemical Co.,Ltd.
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021-58099652-8005 13585536065
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021-58099609
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bin.wu@shlschem.com
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China
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9883
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China DongFan Chemical Co.,LTD
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86-0571-85151182
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86-0571-85151182
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China
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Wuhan Luohua Medical Technology Co.,Ltd.
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13477084141; 13477084141
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+86(27)65566697
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sales@luohuapharm.com
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China
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468
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
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China
ProdList
8669
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57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
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China
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4378
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Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
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China
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17770
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View Lastest Price from METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE manufacturers

Career Henan Chemical Co
Product
METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE 20699-85-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons
Release date
2020-02-03

20699-85-8, METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATERelated Search:

1-Benzothiophen-5-amine METHYL THIOPHENE-2-CARBOXYLATE 2-Thiophenecarboxylic acid Thianaphthene-2-carboxylic acid ETHYL 5-AMINO-3-METHYLBENZO[B]THIOPHENE-2-CARBOXYLATE METHYL 3-AMINO-5-NITROBENZO[B]THIOPHENE-2-CARBOXYLATE ETHYL 3-METHYL-5-NITROBENZO[B]THIOPHENE-2-CARBOXYLATE METHYL 5-([(4-BROMOPHENYL)SULFONYL]AMINO)-1-BENZOTHIOPHENE-2-CARBOXYLATE METHYL 5-(BENZOYLAMINO)-1-BENZOTHIOPHENE-2-CARBOXYLATE METHYL 5-[(4-CHLOROBENZOYL)AMINO]-1-BENZOTHIOPHENE-2-CARBOXYLATE METHYL 5-([(4-METHYLPHENYL)SULFONYL]AMINO)-1-BENZOTHIOPHENE-2-CARBOXYLATE METHYL 5-([(4-CHLOROPHENYL)SULFONYL]AMINO)-1-BENZOTHIOPHENE-2-CARBOXYLATE METHYL 5-([3-(TRIFLUOROMETHYL)BENZOYL]AMINO)-1-BENZOTHIOPHENE-2-CARBOXYLATE METHYL 5-[(4-FLUOROBENZOYL)AMINO]-1-BENZOTHIOPHENE-2-CARBOXYLATE METHYL 3-((4,4-DIMETHYL-2,6-DIOXO(3,5-DIOXANYL))DIAZENYL)-5-NITROBENZO[B]THIOPHENE-2-CARBOXYLATE METHYL 5-([(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO)-1-BENZOTHIOPHENE-2-CARBOXYLATE METHYL 5-[(3-CHLOROBENZOYL)AMINO]-1-BENZOTHIOPHENE-2-CARBOXYLATE METHYL 5-[(PHENYLSULFONYL)AMINO]-1-BENZOTHIOPHENE-2-CARBOXYLATE

  • METHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE
  • ASISCHEM D48912
  • 5-AMINO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
  • methyl 5-aminobenzo[b]thiophene-2-carboxylate
  • 5-Aminothionaphthene-2-carboxylic acid methyl ester
  • ethyl 5-aMinobenzo[b]thiophene-2-carboxylate
  • ethyl thieno[3,2-f]quinoline-2-carboxylate
  • Benzo[b]thiophene-2-carboxylic acid, 5-amino-, methyl ester
  • 20699-85-8