Tricyclazole Property

Melting point:

187-188°C

Boiling point:

275 °C

Density 

1.2292 (rough estimate)

refractive index 

1.5500 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Very Slightly), Methanol

pka

2.40±0.40(Predicted)

Water Solubility 

1.6g/L(25 ºC)

BRN 

980261

InChI

InChI=1S/C9H7N3S/c1-6-3-2-4-7-8(6)12-5-10-11-9(12)13-7/h2-5H,1H3

InChIKey

DQJCHOQLCLEDLL-UHFFFAOYSA-N

SMILES

S1C2=CC=CC(C)=C2N2C=NN=C12

LogP

1.700

CAS DataBase Reference

41814-78-2(CAS DataBase Reference)

NIST Chemistry Reference

Tricyclazole(41814-78-2)

EPA Substance Registry System

Tricyclazole (41814-78-2)

Safety

Hazard Codes 

Xn

Risk Statements 

22

RIDADR 

2588

WGK Germany 

1

RTECS 

XZ5475000

HazardClass 

6.1(a)

PackingGroup 

II

HS Code 

29349990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

Tricyclazole Chemical Properties,Usage,Production

Description

log Kow: 1.4. Solubility: In water at 25 ?C, 1.6 g/L. In acetone 10.4, methanol 25, xylene 2.1 (all in g/l, 25 ?C). Stability: Stable at 52 ?C. Relatively stable to ultraviolet light.

Uses

Tricyclazole is an common active ingredient in several commercial fungicide products used to control rice blast fungus, in transplanted and direct-seeded rice.

Definition

ChEBI: A triazolobenzothiazole that is [1,2,4]triazolo[3,4-b][1,3]benzothiazole which is substituted at position 5 by a methyl group. A fungicide used for the control of rice blast, it is not approved for use within the European Union.

Metabolism

Animals: Rapid and extensive metabolism.
Plants: The principal metabolite is the hydroxymethyl analog.
Soil/Environment: Kd 4 (loamy sand, pH 6.5, 1.5% o.m.), 45 (loam, pH 5.7, 3.1% o.m.), 21 (clay loam, pH 7.4, 1.9% o.m.), 22 (silty clay loam, pH 5.7, 4.1% o.m.).

Toxicity evaluation

Mammalian toxicology. Oral: Acute oral LD₅₀ for rats 314, mice 245, dogs >50 mg/kg. Skin and eye: Acute percutaneous LD₅₀ for rabbits >2000 mg/kg. Slight eye irritant; nonirritating to skin (rabbits). Inhalation: LC50 (1 h) for rats 0.146 mg/L air. NOEL: (2 yr) for rats 9.6 mg/kg b.w.; for mice 6.7 mg/kg b.w.; (1 yr) for dogs 5 mg/kg b.w.; 3-generation reproduction for rat 3 mg/kg b.w. ADI: 0.03 mg/kg.
Toxicity class: World Health Organization (WHO) (a.i.) II; U.S. Environmental Protection Agency (EPA) (formulation) II RC risk Xn (R22). Ecotoxicology. Birds: Acute oral LD₅₀ for mallard ducks and bobwhite quail >100 mg/kg. Fish: LC50 for bluegill sunfish 16.0, rainbow trout 7.3, goldfish fingerlings 13.5 mg/l. Daphnia: LC50 (48 h) > 20 mg/l; NOEC (21 d) 0.96 mg/L.