ChemicalBook > CAS DataBase List > 3-AMINO-2-OXAZOLIDINONE

3-AMINO-2-OXAZOLIDINONE

Product Name: 3-AMINO-2-OXAZOLIDINONE
CAS No.: 80-65-9
Chemical Name: 3-AMINO-2-OXAZOLIDINONE
Synonyms: AOZ;3-Amino-1,3-oxazolidin-2-one;NSC 38250;NSC 196570;NSC 111187;3-Amino-2-ox;AOZ Standard;AOZ in Methanol;AOZ Solution, 100ppm;3-AMINO-OXAZOLIDINONE
CBNumber: CB7430655
Molecular Formula: C3H6N2O2
Formula Weight: 102.09
MOL File: 80-65-9.mol

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3-AMINO-2-OXAZOLIDINONE Property

Melting point:: 65-67 °C
Boiling point:: 135 °C(Press: 0.7 Torr)
Density: 1.179
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 3.24±0.20(Predicted)
color: White to Off-White
BRN: 109430
InChI: InChI=1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2
InChIKey: KYCJNIUHWNJNCT-UHFFFAOYSA-N
SMILES: O1CCN(N)C1=O

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37
WGK Germany: 3
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 33347
Product name: AOZ
Purity: VETRANAL?, analytical standard
Packaging: 50mg
Price: $576
Updated: 2025/07/31

TCI Chemical

Product number: A3404
Product name: 3-Aminooxazolidin-2-one
Purity: min. 98.0 %
Packaging: 100MG
Price: $170
Updated: 2025/07/31

TRC

Product number: A618570
Product name: 3-Amino-2-oxazolidinone
Packaging: 50mg
Price: $130
Updated: 2021/12/16

Usbiological

Product number: 002434
Product name: 3-Amino-2-oxazolidinone
Packaging: 100mg
Price: $460
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA17472
Product name: 3-Amino-2-oxazolidinone
Packaging: 10mg
Price: $60
Updated: 2021/12/16

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3-AMINO-2-OXAZOLIDINONE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A metabolite of Furazolidone and Nitrofuran. Environmental contaminants; Food contaminants; Heat processing contaminants

Definition

ChEBI: 3-Amino-2-oxazolidone is an oxazolidinone.

Synthesis

109-84-2

105-58-8

80-65-9

General procedure for the synthesis of 3-aminooxazolidin-2-one from 2-hydrazinoethanol and diethyl carbonate: 15.2 g (0.2 mol) of 2-hydrazinoethanol (Intermediate 1), 31.0 g (0.2 mol) of diethyl carbonate, and 3.0 g (57 mmol) of sodium methanol were added to a 100 mL three-necked flask, and the mixture was heated and refluxed for 4 hours. Upon completion of the reaction, the reaction mixture was cooled and a solid was precipitated. The solid was collected by vacuum filtration and dried. The solvent in the mother liquor was removed by distillation. The crude product was purified by column chromatography (eluent: methanol/dichloromethane, 1:20, v/v), and the resulting white solid was recrystallized in ethanol to give 15.3 g of 3-aminooxazolidin-2-one (Intermediate 2) in 75% yield. The product was characterized as follows: 1H-NMR (400 MHz, D2O) δ ppm: 4.33 (2H, t, J = 8.0 Hz), 3.94 (2H, s), 3.70 (2H, t, J = 4.0 Hz); EI-MS (m/z): 103.1 [M + H]+; Melting point: 64-66 °C.

References

[1] Patent: EP2952509, 2015, A1. Location in patent: Paragraph 0043; 0044
[2] Journal of the American Chemical Society, 1955, vol. 77, p. 2277,2280, 2281
[3] Journal of the American Chemical Society, 1977, vol. 99, p. 1172 - 1180
[4] Journal of the Chemical Society, 1963, p. 3523 - 3528
[5] Journal of Organic Chemistry, 1966, vol. 31, p. 631 - 632

3-AMINO-2-OXAZOLIDINONE Preparation Products And Raw materials

Raw materials

2-HYDROXYETHYLUREA 2-Oxazolidone

Preparation Products

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View Lastest Price from 3-AMINO-2-OXAZOLIDINONE manufacturers

Honest Joy Holdings Limited

Product: 3-Amino-2-oxazolidinone 80-65-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.4%
Supply Ability: 100 tons
Release date: 2022-02-18

Career Henan Chemical Co

Product: 3-AMINO-2-OXAZOLIDINONE 80-65-9
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-01-02

Career Henan Chemical Co

Product: 3-AMINO-2-OXAZOLIDINONE 80-65-9
Price: US $2.00/KG
Min. Order: 1KG
Purity: ≥99%
Supply Ability: 100kg
Release date: 2019-12-17

80-65-9, 3-AMINO-2-OXAZOLIDINONERelated Search:

2-NP-AOZ Moxnidazole 3-AMINO-2-OXAZOLIDINONE 5-(4-morpholinmethyl)-3-amino-2-oxazolidinone Morphlinomethyl-3-[(5-nitrofurfurylidene)-amino]-2-oxazolidinone 5-((methylthio)methyl)-3-((5-nitrofurfurylidine)amino)-2-oxazolidinon 5-morpholinomethyl-3-(5-nitro-2-furfurylidine-amino)-2-oxazolidinon 3-(((5-Nitro-2-furanyl)methylene)amino)-2-oxazolidinone,3-[[(5-nitro-2-furanyl)methylene]amino]-2-Oxazolidinon Famoxadone Oxadixyl (+)-4-Amino-3-oxazolidinone 5-(Diallylaminomethyl)-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone 3-AMINO-2-OXAZOLIDINONE SULFATE 5-MORPHOLINOMETHYL-3-[5-NITROFURFURYLIDENEAMINO]-2-OXAZOLIDINONE TARTRATE SALT 2-NP-AOZ-D4 5-(4-Morpholinylmethyl-d8)-3-[[(5-nitro-2-furanyl)methylene]amino]-2-oxazolidinone 5-(4-Ethyl-1-piperazinyl)methyl-3-(5-nitrofurfurylidene)amino-2-oxazolidinone 3-AMINO-2-OXAZOLIDINONE D4

3-AMINO-2-OXAZOLIDINONE

AOZ

3-Amino-1,3-oxazolidin-2-one

NSC 111187

NSC 196570

NSC 38250

3-AMINO-OXAZOLIDINONE

3-azanyl-1,3-oxazolidin-2-one

AOZ,3-Amino-2-oxazolidinone

3-Amino-2-oxazolidinone AOZ

3-Amino-oxazolidin-2-one(AOZ)

2-Oxazolidinone,3-amino-(6CI,7CI,8CI,9CI)

3-Amino-2-ox

AOZ Solution, 100ppm

AOZ, 3-Amino-2-oxazolidinone solution,100ppm

2-Oxazolidinone, 3-amino-

3-Aminooxazolidin-2-on

AOZ Standard

Furazolidone Impurity 2

3-Amino-2-oxazolidinone Solution in Methanol, 100μg/mL

C10209000 3-Amino-2-oxazolidinonE(AOZ)

L10209000AL3-Amino-2-oxazolidinonE(AOZ) 10μg

AOZ in Methanol

3-Amino-2-oxazolidinone, 10 mM in DMSO

3-Amino-2-oxazolidinone (AOZ) 100 μg/mL in Acetonitrile

80-65-9

Heterocycles

VARIOUSAMINE

Isoxazoles, Oxadiazoles, Oxazoles

Various Metabolites and Impurities

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals