3-AMINO-2-OXAZOLIDINONE
- Product Name
- 3-AMINO-2-OXAZOLIDINONE
- CAS No.
- 80-65-9
- Chemical Name
- 3-AMINO-2-OXAZOLIDINONE
- Synonyms
- AOZ;3-Amino-1,3-oxazolidin-2-one;NSC 38250;NSC 196570;NSC 111187;3-Amino-2-ox;AOZ Standard;AOZ in Methanol;AOZ Solution, 100ppm;3-AMINO-OXAZOLIDINONE
- CBNumber
- CB7430655
- Molecular Formula
- C3H6N2O2
- Formula Weight
- 102.09
- MOL File
- 80-65-9.mol
3-AMINO-2-OXAZOLIDINONE Property
- Melting point:
- 65-67 °C
- Boiling point:
- 135 °C(Press: 0.7 Torr)
- Density
- 1.179
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 3.24±0.20(Predicted)
- color
- White to Off-White
- BRN
- 109430
- InChI
- InChI=1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2
- InChIKey
- KYCJNIUHWNJNCT-UHFFFAOYSA-N
- SMILES
- O1CCN(N)C1=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 33347
- Product name
- AOZ
- Purity
- VETRANAL?, analytical standard
- Packaging
- 50mg
- Price
- $576
- Updated
- 2025/07/31
- Product number
- A3404
- Product name
- 3-Aminooxazolidin-2-one
- Purity
- min. 98.0 %
- Packaging
- 100MG
- Price
- $170
- Updated
- 2025/07/31
- Product number
- A618570
- Product name
- 3-Amino-2-oxazolidinone
- Packaging
- 50mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 002434
- Product name
- 3-Amino-2-oxazolidinone
- Packaging
- 100mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- CHM0010233
- Product name
- 3-AMINO-2-OXAZOLIDINONE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $739.2
- Updated
- 2021/12/16
3-AMINO-2-OXAZOLIDINONE Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
A metabolite of Furazolidone and Nitrofuran. Environmental contaminants; Food contaminants; Heat processing contaminants
Definition
ChEBI: 3-Amino-2-oxazolidone is an oxazolidinone.
Synthesis
109-84-2
105-58-8
80-65-9
General procedure for the synthesis of 3-aminooxazolidin-2-one from 2-hydrazinoethanol and diethyl carbonate: 15.2 g (0.2 mol) of 2-hydrazinoethanol (Intermediate 1), 31.0 g (0.2 mol) of diethyl carbonate, and 3.0 g (57 mmol) of sodium methanol were added to a 100 mL three-necked flask, and the mixture was heated and refluxed for 4 hours. Upon completion of the reaction, the reaction mixture was cooled and a solid was precipitated. The solid was collected by vacuum filtration and dried. The solvent in the mother liquor was removed by distillation. The crude product was purified by column chromatography (eluent: methanol/dichloromethane, 1:20, v/v), and the resulting white solid was recrystallized in ethanol to give 15.3 g of 3-aminooxazolidin-2-one (Intermediate 2) in 75% yield. The product was characterized as follows: 1H-NMR (400 MHz, D2O) δ ppm: 4.33 (2H, t, J = 8.0 Hz), 3.94 (2H, s), 3.70 (2H, t, J = 4.0 Hz); EI-MS (m/z): 103.1 [M + H]+; Melting point: 64-66 °C.
References
[1] Patent: EP2952509, 2015, A1. Location in patent: Paragraph 0043; 0044
[2] Journal of the American Chemical Society, 1955, vol. 77, p. 2277,2280, 2281
[3] Journal of the American Chemical Society, 1977, vol. 99, p. 1172 - 1180
[4] Journal of the Chemical Society, 1963, p. 3523 - 3528
[5] Journal of Organic Chemistry, 1966, vol. 31, p. 631 - 632
3-AMINO-2-OXAZOLIDINONE Preparation Products And Raw materials
Raw materials
Preparation Products
3-AMINO-2-OXAZOLIDINONE Suppliers
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- Country
- Germany
- ProdList
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- Advantage
- 66
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View Lastest Price from 3-AMINO-2-OXAZOLIDINONE manufacturers
- Product
- 3-Amino-2-oxazolidinone 80-65-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.4%
- Supply Ability
- 100 tons
- Release date
- 2022-02-18
- Product
- 3-AMINO-2-OXAZOLIDINONE 80-65-9
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-01-02
- Product
- 3-AMINO-2-OXAZOLIDINONE 80-65-9
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2019-12-17