5-BROMO-PYRAZINE-2,3-DIAMINE
- Product Name
- 5-BROMO-PYRAZINE-2,3-DIAMINE
- CAS No.
- 89123-58-0
- Chemical Name
- 5-BROMO-PYRAZINE-2,3-DIAMINE
- Synonyms
- 2,3-Diamino-5-bromopyrazine;5-Bromo-2,3-pyrazinediamine;5-BROMO-2,3-DIAMINOPYRAZINE;5-BROMO-PYRAZINE-2,3-DIAMINE;2,3-Pyrazinediamine, 5-bromo-;Pyrazine, 2,3-diamino-5-bromo-;2,3-DIAMINO-5-BROMOPYRAZINE, 97%;5-BROMO-PYRAZINE-2,3-DIAMINE ISO 9001:2015 REACH
- CBNumber
- CB7438873
- Molecular Formula
- C4H5BrN4
- Formula Weight
- 189.01
- MOL File
- 89123-58-0.mol
5-BROMO-PYRAZINE-2,3-DIAMINE Property
- Melting point:
- 212-216 °C (dec.)
- Boiling point:
- 357.1±37.0 °C(Predicted)
- Density
- 1.956±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- pka
- 2.72±0.10(Predicted)
- color
- light brown
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-43
- Safety Statements
- 26-36/37
- WGK Germany
- 3
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 685763
- Product name
- 2,3-Diamino-5-bromopyrazine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $101
- Updated
- 2023/06/20
- Product number
- D415070
- Product name
- 2,3-Diamino-5-bromopyrazine
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- D415070
- Product name
- 2,3-Diamino-5-bromopyrazine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 072225
- Product name
- 5-Bromo-2,3-diaminopyrazine
- Purity
- 95+%
- Packaging
- 10g
- Price
- $1000
- Updated
- 2021/12/16
- Product number
- 3H30-9-V4
- Product name
- 5-Bromopyrazine-2,3-diamine
- Packaging
- 5G
- Price
- $495
- Updated
- 2021/12/16
5-BROMO-PYRAZINE-2,3-DIAMINE Chemical Properties,Usage,Production
Uses
2,3-Diamino-5-bromopyrazine
Synthesis
24241-18-7
89123-58-0
The general procedure for the synthesis of 5-bromo-2,3-diaminopyrazine from 2-amino-3,5-dibromopyrazine was as follows: step 1: 2-amino-3,5-dibromopyrazine (3 g, 11.64 mmol) was suspended in a 25% aqueous ammonia solution (15 mL) in a sealed tube and the reaction was heated for 16 h at 110 °C. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was partitioned between ethyl acetate and water (3 x 50 mL). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography with 15% ethyl acetate-hexane mixed solvent as eluent to afford 5-bromo-2,3-diaminopyrazine as a yellow solid (2.1 g, 93% yield). Mass spectrum (electrospray ionization) m/z: 189 ([M+H]+).
References
[1] Patent: US2011/59118, 2011, A1. Location in patent: Page/Page column 81-82
[2] Bioorganic and Medicinal Chemistry, 1999, vol. 7, # 6, p. 1059 - 1065
[3] Patent: WO2017/64068, 2017, A1. Location in patent: Page/Page column 59; 60
[4] Patent: TWI523856, 2016, B. Location in patent: Paragraph 0078
[5] Patent: CN108395436, 2018, A. Location in patent: Paragraph 0010
5-BROMO-PYRAZINE-2,3-DIAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
5-BROMO-PYRAZINE-2,3-DIAMINE Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 86-25-57062118
- Fax
- 86-25-57065896
- sales@jspsn.com
- Country
- China
- ProdList
- 496
- Advantage
- 57
- Tel
- +86 (21) 6435-5022
- Country
- China
- ProdList
- 4267
- Advantage
- 65
- Tel
- 0512-63263366 18912765016
- Fax
- 0512-6326 3366
- tongtf110@sina.com
- Country
- China
- ProdList
- 993
- Advantage
- 62
View Lastest Price from 5-BROMO-PYRAZINE-2,3-DIAMINE manufacturers
- Product
- 5-BROMO-PYRAZINE-2,3-DIAMINE 89123-58-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 5-BROMO-PYRAZINE-2,3-DIAMINE 89123-58-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 5-BROMO-PYRAZINE-2,3-DIAMINE 89123-58-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500kg
- Release date
- 2018-08-19