ChemicalBook > CAS DataBase List > 5-BROMO-PYRAZINE-2,3-DIAMINE

5-BROMO-PYRAZINE-2,3-DIAMINE

Product Name
5-BROMO-PYRAZINE-2,3-DIAMINE
CAS No.
89123-58-0
Chemical Name
5-BROMO-PYRAZINE-2,3-DIAMINE
Synonyms
2,3-Diamino-5-bromopyrazine;5-Bromo-2,3-pyrazinediamine;5-BROMO-2,3-DIAMINOPYRAZINE;5-BROMO-PYRAZINE-2,3-DIAMINE;2,3-Pyrazinediamine, 5-bromo-;Pyrazine, 2,3-diamino-5-bromo-;2,3-DIAMINO-5-BROMOPYRAZINE, 97%;5-BROMO-PYRAZINE-2,3-DIAMINE ISO 9001：2015 REACH
CBNumber
CB7438873
Molecular Formula
C4H5BrN4
Formula Weight
189.01
MOL File
89123-58-0.mol
More
Less

5-BROMO-PYRAZINE-2,3-DIAMINE Property

Melting point:
212-216 °C (dec.)
Boiling point:
357.1±37.0 °C(Predicted)
Density 
1.956±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
solid
pka
2.72±0.10(Predicted)
color 
light brown
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-43
Safety Statements 
26-36/37
WGK Germany 
3
HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
685763
Product name
2,3-Diamino-5-bromopyrazine
Purity
97%
Packaging
250mg
Price
$101
Updated
2023/06/20
TRC
Product number
D415070
Product name
2,3-Diamino-5-bromopyrazine
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
D415070
Product name
2,3-Diamino-5-bromopyrazine
Packaging
1g
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
072225
Product name
5-Bromo-2,3-diaminopyrazine
Purity
95+%
Packaging
10g
Price
$1000
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-9-V4
Product name
5-Bromopyrazine-2,3-diamine
Packaging
5G
Price
$495
Updated
2021/12/16
More
Less

5-BROMO-PYRAZINE-2,3-DIAMINE Chemical Properties,Usage,Production

Uses

2,3-Diamino-5-bromopyrazine

Synthesis

24241-18-7

89123-58-0

The general procedure for the synthesis of 5-bromo-2,3-diaminopyrazine from 2-amino-3,5-dibromopyrazine was as follows: step 1: 2-amino-3,5-dibromopyrazine (3 g, 11.64 mmol) was suspended in a 25% aqueous ammonia solution (15 mL) in a sealed tube and the reaction was heated for 16 h at 110 °C. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was partitioned between ethyl acetate and water (3 x 50 mL). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography with 15% ethyl acetate-hexane mixed solvent as eluent to afford 5-bromo-2,3-diaminopyrazine as a yellow solid (2.1 g, 93% yield). Mass spectrum (electrospray ionization) m/z: 189 ([M+H]+).

References

[1] Patent: US2011/59118, 2011, A1. Location in patent: Page/Page column 81-82
[2] Bioorganic and Medicinal Chemistry, 1999, vol. 7, # 6, p. 1059 - 1065
[3] Patent: WO2017/64068, 2017, A1. Location in patent: Page/Page column 59; 60
[4] Patent: TWI523856, 2016, B. Location in patent: Paragraph 0078
[5] Patent: CN108395436, 2018, A. Location in patent: Paragraph 0010

5-BROMO-PYRAZINE-2,3-DIAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-BROMO-PYRAZINE-2,3-DIAMINE Suppliers

China 99 Czech Republic 1 Germany 2 Hungary 1 India 2 Switzerland 1 United Kingdom 3 United States 14 Global 123
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
More
Less

View Lastest Price from 5-BROMO-PYRAZINE-2,3-DIAMINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
5-BROMO-PYRAZINE-2,3-DIAMINE 89123-58-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-BROMO-PYRAZINE-2,3-DIAMINE 89123-58-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
5-BROMO-PYRAZINE-2,3-DIAMINE 89123-58-0
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500kg
Release date
2018-08-19

89123-58-0, 5-BROMO-PYRAZINE-2,3-DIAMINERelated Search:

2-AMINO-5-BROMO-3-PIPERIDIN-1-YLPYRAZINE 5-BROMO-N3-METHYL-PYRAZINE-2,3-DIAMINE 2-AMINO-5-BROMO-3-(DIMETHYLAMINO)PYRAZINE 2-AMINO-5-BROMO-3-HYDRAZINOPYRAZINE 2-AMINO-5-BROMO-3-(ETHYLAMINO)PYRAZINE 5-BROMO-PYRAZINE-2,3-DIAMINE 2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE 2-AMINO-5-BROMO-3-PYRROLIDIN-1-YLPYRAZINE 2-AMINO-5-BROMO-3-PIPERAZIN-1-YLPYRAZINE 2-AMINO-5-BROMO-3-(DIETHYLAMINO)PYRAZINE Aminopyrazine 6'-BROMO-3-PHENYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRAZINYL-3'-YLAMINE 5-BROMO-3-[1,4]DIAZEPAN-1-YL-PYRAZIN-2-YLAMINE 5-BROMO-3-(2-PYRIDIN-3-YL-PYRROLIDIN-1-YL)-PYRAZIN-2-YLAMINE 6'-BROMO-3-METHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRAZINYL-3'-YLAMINE 5-BROMO-3-(2-PYRIDIN-2-YL-PYRROLIDIN-1-YL)-PYRAZIN-2-YLAMINE 5-BROMO-3-(2-PHENYL-PYRROLIDIN-1-YL)-PYRAZIN-2-YLAMINE 5-BROMO-3-[(4-METHOXYBENZYL)AMINO]PYRAZIN-2-AMINE

  • 5-BROMO-2,3-DIAMINOPYRAZINE
  • 5-BROMO-PYRAZINE-2,3-DIAMINE
  • 2,3-DIAMINO-5-BROMOPYRAZINE, 97%
  • Pyrazine, 2,3-diamino-5-bromo-
  • 2,3-Pyrazinediamine, 5-bromo-
  • 5-BROMO-PYRAZINE-2,3-DIAMINE ISO 9001：2015 REACH
  • 5-Bromo-2,3-pyrazinediamine
  • 2,3-Diamino-5-bromopyrazine
  • 89123-58-0
  • New Products for Chemical Synthesis May/June 2007