ChemicalBook > CAS DataBase List > 5-BROMO-PYRAZINE-2,3-DIAMINE

5-BROMO-PYRAZINE-2,3-DIAMINE

Product Name
5-BROMO-PYRAZINE-2,3-DIAMINE
CAS No.
89123-58-0
Chemical Name
5-BROMO-PYRAZINE-2,3-DIAMINE
Synonyms
2,3-Diamino-5-bromopyrazine;5-Bromo-2,3-pyrazinediamine;5-BROMO-2,3-DIAMINOPYRAZINE;5-BROMO-PYRAZINE-2,3-DIAMINE;2,3-Pyrazinediamine, 5-bromo-;Pyrazine, 2,3-diamino-5-bromo-;2,3-DIAMINO-5-BROMOPYRAZINE, 97%;5-BROMO-PYRAZINE-2,3-DIAMINE ISO 9001：2015 REACH
CBNumber
CB7438873
Molecular Formula
C4H5BrN4
Formula Weight
189.01
MOL File
89123-58-0.mol
More
Less

5-BROMO-PYRAZINE-2,3-DIAMINE Property

Melting point:
212-216 °C (dec.)
Boiling point:
357.1±37.0 °C(Predicted)
Density 
1.956±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
solid
pka
2.72±0.10(Predicted)
color 
light brown
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-43
Safety Statements 
26-36/37
WGK Germany 
3
HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
685763
Product name
2,3-Diamino-5-bromopyrazine
Purity
97%
Packaging
250mg
Price
$101
Updated
2023/06/20
TRC
Product number
D415070
Product name
2,3-Diamino-5-bromopyrazine
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
D415070
Product name
2,3-Diamino-5-bromopyrazine
Packaging
1g
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
072225
Product name
5-Bromo-2,3-diaminopyrazine
Purity
95+%
Packaging
10g
Price
$1000
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-9-V4
Product name
5-Bromopyrazine-2,3-diamine
Packaging
5G
Price
$495
Updated
2021/12/16
More
Less

5-BROMO-PYRAZINE-2,3-DIAMINE Chemical Properties,Usage,Production

Uses

2,3-Diamino-5-bromopyrazine

Synthesis

24241-18-7

89123-58-0

The general procedure for the synthesis of 5-bromo-2,3-diaminopyrazine from 2-amino-3,5-dibromopyrazine was as follows: step 1: 2-amino-3,5-dibromopyrazine (3 g, 11.64 mmol) was suspended in a 25% aqueous ammonia solution (15 mL) in a sealed tube and the reaction was heated for 16 h at 110 °C. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was partitioned between ethyl acetate and water (3 x 50 mL). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography with 15% ethyl acetate-hexane mixed solvent as eluent to afford 5-bromo-2,3-diaminopyrazine as a yellow solid (2.1 g, 93% yield). Mass spectrum (electrospray ionization) m/z: 189 ([M+H]+).

References

[1] Patent: US2011/59118, 2011, A1. Location in patent: Page/Page column 81-82
[2] Bioorganic and Medicinal Chemistry, 1999, vol. 7, # 6, p. 1059 - 1065
[3] Patent: WO2017/64068, 2017, A1. Location in patent: Page/Page column 59; 60
[4] Patent: TWI523856, 2016, B. Location in patent: Paragraph 0078
[5] Patent: CN108395436, 2018, A. Location in patent: Paragraph 0010

5-BROMO-PYRAZINE-2,3-DIAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-BROMO-PYRAZINE-2,3-DIAMINE Suppliers

China 99 Czech Republic 1 Germany 2 Hungary 1 India 2 Switzerland 1 United Kingdom 3 United States 14 Global 123
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
PSN Pharmaceutical Technology Co., Ltd.
Tel
86-25-57062118
Fax
86-25-57065896
Email
sales@jspsn.com
Country
China
ProdList
496
Advantage
57
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
993
Advantage
62
Shanghai yirong biology science and technology co., ltd
Tel
18049974220
Fax
+86 (21) 51062076
Email
3060526242@qq.com
Country
China
ProdList
995
Advantage
60
Kohn & Shawn Pharmatech Co.,Ltd
Tel
0931-4190454 13893344397
Fax
+86-931-8506154
Email
sales@kyxpharma.com
Country
China
ProdList
310
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Shanghai Keepontech Co.,Ltd
Tel
021-54849683 13601642561
Fax
+86-21-54375689
Email
sales@keepontech.com
Country
China
ProdList
998
Advantage
59
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Chainpharm Bio-medical Technology Co., Ltd.
Tel
+86-021-61727342 13611721451
Fax
021-61294107
Email
chainpharm@163.com
Country
China
ProdList
980
Advantage
58
Beijin Yangguang Furui Chemical co.,Ltd.
Tel
010-57495520 13521095525
Email
zhw512@foxmail.com
Country
China
ProdList
488
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Nanjing Fast Bio-Pharmaceutical Co.,Ltd.
Tel
025-58390181 58390186 18912901218
Fax
025-58390182
Email
sales@fastchem.cn
Country
China
ProdList
162
Advantage
60
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
6295
Advantage
60
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10263
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Bellen Chemistry Co., Ltd.
Tel
010-60400365-8001 15910885229
Fax
010-60400361
Email
service@bellenchem.com
Country
China
ProdList
4514
Advantage
60
Wuhan Chemwish Technology Co.， Ltd
Tel
027-67849912
Fax
027-87531808
Email
sales@chemwish.com
Country
China
ProdList
9148
Advantage
60
Yancheng KangdiSen Pharmaceutical Co., Ltd.
Tel
13812573443
Fax
-
Email
tongbenwan22@163.com
Country
China
ProdList
1980
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Wuhan Greenkj Pharmaceutical Technology Co., Ltd.
Tel
15608630565
Fax
-
Email
greenkjpharm@163.com
Country
China
ProdList
130
Advantage
58
Shenzhen Simeiquan Biotechnology Co. Ltd
Tel
18126413629 0755-23311925 2355327053
Fax
0755-23311925
Email
abel@ycgmp.com
Country
China
ProdList
5113
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shenzhen Sendi Biological Technology Co., Ltd.
Tel
18124570582 TEL：0755-23574479 2355327139
Fax
0755-23229476 QQ: 2355327139
Email
siliao02@yccreate.com
Country
China
ProdList
6116
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
Advantage
60
Jiaxing Deyi Chemical Co., Ltd.
Tel
86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8595
Advantage
58
Zhuhai JiaYi Biological Technology Co., Ltd.
Tel
18578209868 2355327026
Fax
18578209868 QQ：2355327026
Email
steroidbest@hotmail.com
Country
China
ProdList
6501
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
14948
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Foshan DaoQi Biological Co., Ltd.
Tel
18062666947
Fax
18062666959
Email
2355880548@qq.com
Country
China
ProdList
4228
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6039 18920764717
Email
sales@heowns.com
Country
China
ProdList
23771
Advantage
60
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
Lanzhou Kangyuxin Biotechnology Co., Ltd.
Tel
0931-4190454 13893344397
Email
sales@kyxpharma.com
Country
China
ProdList
3151
Advantage
58
Suzhou Rovathin Foreign Trade Co.,Ltd
Tel
0512-65816829 18662214788
Fax
0512-65816829
Email
info@rovathin.com.cn
Country
China
ProdList
9987
Advantage
58
Henan Alfa Chemical Co., Ltd
Tel
+8615838112936
Email
alfa10@alfachem.cn
Country
China
ProdList
12921
Advantage
58
Nanjing Hengbei Chemicals Co., Ltd.
Tel
+86-25-58393656
Fax
+86-25-58393656
Email
sales@hengbeichem.cn
Country
China
ProdList
6854
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
20284
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Baoji Guokang Healthchem Co., Ltd.
Tel
+86-0917-3909592 +86-13892490616
Fax
09173909592
Email
gksales1@gk-bio.com
Country
China
ProdList
9209
Advantage
58
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
ProdList
23912
Advantage
58
More
Less

View Lastest Price from 5-BROMO-PYRAZINE-2,3-DIAMINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
5-BROMO-PYRAZINE-2,3-DIAMINE 89123-58-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-BROMO-PYRAZINE-2,3-DIAMINE 89123-58-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
5-BROMO-PYRAZINE-2,3-DIAMINE 89123-58-0
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500kg
Release date
2018-08-19

89123-58-0, 5-BROMO-PYRAZINE-2,3-DIAMINERelated Search:

2-AMINO-5-BROMO-3-PIPERIDIN-1-YLPYRAZINE 5-BROMO-N3-METHYL-PYRAZINE-2,3-DIAMINE 2-AMINO-5-BROMO-3-(DIMETHYLAMINO)PYRAZINE 2-AMINO-5-BROMO-3-HYDRAZINOPYRAZINE 2-AMINO-5-BROMO-3-(ETHYLAMINO)PYRAZINE 5-BROMO-PYRAZINE-2,3-DIAMINE 2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE 2-AMINO-5-BROMO-3-PYRROLIDIN-1-YLPYRAZINE 2-AMINO-5-BROMO-3-PIPERAZIN-1-YLPYRAZINE 2-AMINO-5-BROMO-3-(DIETHYLAMINO)PYRAZINE Aminopyrazine 6'-BROMO-3-PHENYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRAZINYL-3'-YLAMINE 5-BROMO-3-[1,4]DIAZEPAN-1-YL-PYRAZIN-2-YLAMINE 5-BROMO-3-(2-PYRIDIN-3-YL-PYRROLIDIN-1-YL)-PYRAZIN-2-YLAMINE 6'-BROMO-3-METHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRAZINYL-3'-YLAMINE 5-BROMO-3-(2-PYRIDIN-2-YL-PYRROLIDIN-1-YL)-PYRAZIN-2-YLAMINE 5-BROMO-3-(2-PHENYL-PYRROLIDIN-1-YL)-PYRAZIN-2-YLAMINE 5-BROMO-3-[(4-METHOXYBENZYL)AMINO]PYRAZIN-2-AMINE

  • 5-BROMO-2,3-DIAMINOPYRAZINE
  • 5-BROMO-PYRAZINE-2,3-DIAMINE
  • 2,3-DIAMINO-5-BROMOPYRAZINE, 97%
  • Pyrazine, 2,3-diamino-5-bromo-
  • 2,3-Pyrazinediamine, 5-bromo-
  • 5-BROMO-PYRAZINE-2,3-DIAMINE ISO 9001：2015 REACH
  • 5-Bromo-2,3-pyrazinediamine
  • 2,3-Diamino-5-bromopyrazine
  • 89123-58-0
  • New Products for Chemical Synthesis May/June 2007