6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine

Product Name: 6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine
CAS No.: 88965-00-8
Chemical Name: 6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine
Synonyms: O4I3;SKL362;Zolpidem Impurity 32;Zolpidem tartrate Impurity 16;6-methyl-2-p-tolylimidazo[1,2-a]pyridin;6-METHYL-2-P-TOLY-IIDAZOLE(1,2)PYRIDINE;6-METHYL-2-P-TOLYL-IMIDAZO[1,2-A]PYRIDINE;6-methyl-2-(4-methylphenyl)1,2-a] pyruffs;[2-(4-methylpheny)-6-methyl[1,2-a]imidazopyridine;6-Methyl-2-(4-methylphenyl-imidazo[1,2-a]pyridine
CBNumber: CB7443932
Molecular Formula: C15H14N2
Formula Weight: 222.29
MOL File: 88965-00-8.mol

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6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine Property

Melting point:: 205-207°C
Density: 1.09±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 7.07±0.50(Predicted)
form: Solid
color: White to Off-White
CAS DataBase Reference: 88965-00-8(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2886
Product name: O4I3
Purity: ≥98%(HPLC)
Packaging: 5MG
Price: $70.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2886
Product name: O4I3
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $229
Updated: 2024/03/01

TRC

Product number: M322050
Product name: 6-Methyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine
Packaging: 10g
Price: $1390
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0027828
Product name: 6-METHYL-2-P-TOLYL-IMIDAZO[1,2-A]PYRIDINE
Purity: 95.00%
Packaging: 5G
Price: $1042.97
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 47558
Product name: 6-Methyl-2-(4-methylphenyl)-imidazo[1,2-α]pyridine
Packaging: 100mg
Price: $650
Updated: 2021/12/16

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6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine Chemical Properties,Usage,Production

Uses

6-Methyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine is an impurity of Zolpidem (Z650000), a selective non-benzodiazepine GABAA receptor agonist.

Biological Activity

O4I3 is a highly potent and KDM5A (JARID1A) subtype-selective H3K4 demethylase KDM5 inhibitor (KDM5A IC50 = 0.15 nM vs KDM5B/C/D IC50 = 125.2/9.76/4.7 nM, KDM4 IC50 = 249 nM, LSD1 IC50 >100 μM) th at effectively induces OCT4 expresson and improves OSKM-induced pluripotent stem cell (iPSC) reprogramming efficiency of human primary fibroblasts (50 nM) by preventing KDM5A from interfering with H3K4Me3 enrichment at the OCT4 promoter. O4I3 promotes hPSC homeostasis and represses cellular differentiation, increasing hPSCs viability up to 4-fold at a low 10 nM concentration when compared with Rock inhibitor Y-27632 treatment at 10 μM.

6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine Suppliers

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View Lastest Price from 6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine manufacturers

Career Henan Chemical Co

Product: 6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine 88965-00-8
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-03

88965-00-8, 6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridineRelated Search:

Paraquat dichloride Methylparaben Methanol Acetonitrile 2,6-Lutidine Methyl acrylate Chlorodimethylphenylsilane 1-Methylimidazole Zolpidem tartrate 6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid 2,4,6-Collidine Kresoxim-methyl Basic Violet 1 4-Methylpyridine Pyridine Methyl 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetate Methyl 2,2-DIBROMO-1-P-TOLYLETHANONE

6-methyl-2-(4-methylphenyl)imidazo[1,2-alpha]pyridine

6-Methyl-2-(4-methylphenyl-imidazo[1,2-a]pyridine

6-METHYL-2-P-TOLYL-IMIDAZO[1,2-A]PYRIDINE

ZolpidemTartrate1.6-Methyl-2-(4-Methylphenyl)Imidazo[1,2-A]Pyridine

IMIDAZO[1,2-A]PYRIDINE, 6-METHYL-2-(4-METHYLPHENYL)-

6-METHYL-2-P-TOLY-IIDAZOLE(1,2)PYRIDINE

6-methyl-2-p-tolylimidazo[1,2-a]pyridin

Zolpidem Impurity 32

[2-(4-methylpheny)-6-methyl[1,2-a]imidazopyridine

Zolpidem tartrate Impurity 16

SKL362

6-methyl-2-(4-methylphenyl)1,2-a] pyruffs

6-methyl-2-(4-methylphenyl)Imidazole[1,2-a] pyruffs

O4I3

88965-00-8

Pyridines derivates