ChemicalBook > CAS DataBase List > 5-Hydroxynicotinic acid
5-Hydroxynicotinic acid
- Product Name
- 5-Hydroxynicotinic acid
- CAS No.
- 27828-71-3
- Chemical Name
- 5-Hydroxynicotinic acid
- Synonyms
- AKOS NCG-0022;5-Hydroxynicotinic;Nicotinic acid-004;TIMTEC-BB SBB010273;5-Hydroxynicotinic a;5-hydroxy-nicotinicaci;5-Hydroxy nicotic acid;5-HYDROXYNICOTINIC ACID;Hydroxynicotinicacid 5-;5-HydroxynicotinicAcid>
- CBNumber
- CB7447677
- Molecular Formula
- C6H5NO3
- Formula Weight
- 139.11
- MOL File
- 27828-71-3.mol
More
Less
5-Hydroxynicotinic acid Property
- Melting point:
- 299 °C
- Boiling point:
- 519.3±35.0 °C(Predicted)
- Density
- 1.485±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 2.08±0.10(Predicted)
- form
- powder to crystal
- color
- White to Yellow
- BRN
- 115847
- InChI
- InChI=1S/C6H5NO3/c8-5-1-4(6(9)10)2-7-3-5/h1-3,8H,(H,9,10)
- InChIKey
- ATTDCVLRGFEHEO-UHFFFAOYSA-N
- SMILES
- C1=NC=C(O)C=C1C(O)=O
- CAS DataBase Reference
- 27828-71-3(CAS DataBase Reference)
More
Less
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 672742
- Product name
- 5-Hydroxynicotinic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $114
- Updated
- 2021/12/16
Sigma-Aldrich
- Product number
- 672742
- Product name
- 5-Hydroxynicotinic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $452
- Updated
- 2021/12/16
TCI Chemical
- Product number
- H1226
- Product name
- 5-Hydroxynicotinic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $90
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- H30725
- Product name
- 5-Hydroxynicotinic acid, 97%
- Packaging
- 5g
- Price
- $131
- Updated
- 2021/12/16
Alfa Aesar
- Product number
- H30725
- Product name
- 5-Hydroxynicotinic acid, 97%
- Packaging
- 1g
- Price
- $41
- Updated
- 2021/12/16
More
Less
5-Hydroxynicotinic acid Chemical Properties,Usage,Production
Chemical Properties
White to off-white to yellow solid
Uses
5-Hydroxynicotinic acid is a nicotinic acid analog with potential inhibitory effect on the metabolism nicotinic acid by human platelets. Used in the investigation of the hydroxylation mechanism of the flaovoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO).
Definition
ChEBI: 5-Hydroxynicotinic acid is an aromatic carboxylic acid and a member of pyridines.
Research
5-hydroxynicotinic acid (5HNA) could be used as a model the following questions were addressed: (i) is it possible to promote the crystallization of a tautomeric form dominant in a specific solvent through solvate formation? (ii) Does that form persist if the memory of solvation is erased through thermal desolvation?
A thermodynamic analysis based on DSC and Calvet drop microcalorimetry results allowed us to rationalize these observations, indicating that (i) 5HNA·H2O is predicted to spontaneously lose water, even for a relative humidity of 100%, hence its robustness is most certainly of kinetical origin; (ii) 5HNA·DMSO is thermodynamically stable when a saturation DMSO pressure can be established over the sample, but becomes unstable when exposed to an atmosphere where the solvent is absent. The kinetically easier desolvation of 5HNA·DMSO compared to 5HNA·H2O may be related to the fact that water is isolated in the crystal lattice (isolated site hydrate) while DMSO is placed in channels (channel solvate)[1].
References
[1] Joseph, Abhinav et al. “Tautomer selection through solvate formation: the case of 5-hydroxynicotinic acid?.” CrystEngComm 13 (2019): 2220–2233.
5-Hydroxynicotinic acid Preparation Products And Raw materials
Raw materials
5-Aminonicotinic acid
Ethanol
Sodium nitrite
Ethyl acetate
Dichloromethane
Sodium hydroxide
Thionyl chloride
Sulfuric acid
Preparation Products
More
Less
5-Hydroxynicotinic acid Suppliers
- Tel
- 0311-89805679 +86-13463963265
- Fax
- 0311-85262695
- sell@dowechem.com
- Country
- China
- ProdList
- 50
- Advantage
- 62
- Tel
- 0311-88800819 13932107110
- Fax
- 86-0311-85111404
- sales@jztchem.com
- Country
- China
- ProdList
- 14
- Advantage
- 62
- Tel
- 021-54450827 021-54450828
- sales@fwdchem.com
- Country
- China
- ProdList
- 1000
- Advantage
- 58
- Tel
- 15951679563
- 2853992905@qq.com
- Country
- China
- ProdList
- 8136
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
- Advantage
- 69
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- sales@jonln.com
- Country
- China
- ProdList
- 1995
- Advantage
- 65
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44688
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- sales@capotchem.com
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-82967028 13552068683
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12390
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9512
- Advantage
- 66
- Tel
- 28-83379370 13880556291
- Fax
- 028-87747383
- tcy@tcypharm.com
- Country
- China
- ProdList
- 510
- Advantage
- 57
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14103
- Advantage
- 59
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11655
- Advantage
- 64
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9810
- Advantage
- 59
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 19179
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42958
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 15402
- Advantage
- 60
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- 15527768850
- 1791901229@qq.com
- Country
- China
- ProdList
- 8836
- Advantage
- 52
- Tel
- 010-82954736 13391601435
- sales@isomersyn.com
- Country
- China
- ProdList
- 3295
- Advantage
- 57
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18738
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9815
- Advantage
- 79
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
- Country
- China
- ProdList
- 9387
- Advantage
- 52
- Tel
- 0370-2785118 17550508557
- Fax
- QQ：3470079902
- 675141927@qq.com
- Country
- China
- ProdList
- 3203
- Advantage
- 55
- Tel
- 027-59207852 13308628970
- Fax
- QQ3130921841
- buy@fortunachem.com
- Country
- China
- ProdList
- 2865
- Advantage
- 58
- Tel
- 021-54824098, 021-37212705 021-37212706, 13391256916
- Fax
- 021-54824069
- sales@chemzq.com
- Country
- China
- ProdList
- 570
- Advantage
- 55
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- 0512-65617459 18915409046
- Fax
- 0512-65617459
- sales@sibian-chem.com
- Country
- China
- ProdList
- 1922
- Advantage
- 55
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9458
- Advantage
- 58
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 400-400-6206333 18521732826
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 021-61552785
- Fax
- 021-55660885
- sales@shshiji.com
- Country
- China
- ProdList
- 9545
- Advantage
- 55
- Tel
- sales@witofly.com
- Country
- China
- ProdList
- 2864
- Advantage
- 52
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 025-52164950
- Fax
- 025-86800069
- Googlexu_0114@sina.com
- Country
- China
- ProdList
- 644
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41462
- Advantage
- 60
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- Country
- China
- ProdList
- 2930
- Advantage
- 58
- Tel
- +86 574 8729 6330
- Fax
- +86 574 8729 7461
- info@chemik.com
- Country
- China
- ProdList
- 3616
- Advantage
- 61
- Tel
- 0371-13526885213 15637198702
- Fax
- 0371-63709726
- xpkchem@163.com
- Country
- China
- ProdList
- 3978
- Advantage
- 58
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9346
- Advantage
- 58
More
Less
View Lastest Price from 5-Hydroxynicotinic acid manufacturers
Hebei Zhuanglai Chemical Trading Co Ltd
- Product
- 5-Hydroxynicotinic acid 27828-71-3
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-19
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- 5-Hydroxynicotinic acid 27828-71-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-07
Shijiazhuang Dowell Chemical Co.,Ltd
- Product
- 5-Hydroxynicotinic acid 27828-71-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2MT/Month
- Release date
- 2024-12-03
27828-71-3, 5-Hydroxynicotinic acid Related Search:
Ethyl 2-(Chlorosulfonyl)acetate
Glycolic acid
Hydroxy silicone oil
Folic acid
Chrysin
4-Hydroxybenzaldehyde
HYDROXYAPATITE TYPE I
10-Hydroxycamptothecin
Methylparaben
Glycine
CHLOROPHOSPHONAZO III
2-Hydroxy-5-pyridinecarboxylic acid
2-Hydroxynicotinic acid 98%,2-HYDROXYNICOTINIC ACID,2-Hydroxynicotinic acid, 2-Hydroxypyridine-3-carboxylic acid,2-Hydroxynicotinic acid ,98%
Glycolonitrile
4-HYDROXYNICOTINIC ACID,4-Hydroxynicotinic acid ,97%
5-HYDROXYNICOTINIC ACID METHYL ESTER,5-HYDROXYNICOTINIC ACID METHYL ESTER 98+%
5-Methoxy-3-pyridinemethanamine
METHYL 6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLATE