ChemicalBook > CAS DataBase List > (5-Methylisoxazol-3-yl)methanol
(5-Methylisoxazol-3-yl)methanol
- Product Name
- (5-Methylisoxazol-3-yl)methanol
- CAS No.
- 35166-33-7
- Chemical Name
- (5-Methylisoxazol-3-yl)methanol
- Synonyms
- -3-YL;EOS-61616;AKOS PAO-1431;(5-Methylisoxa;BUTTPARK 27\08-49;SALOR-INT L482684-1EA;5-Methylisoxazol-3-methanol;5-Methylisoxazole-3-Methanol;(5-Methylisoxazol-3-yl)Metha;3-Isoxazolemethanol, 5-methyl-
- CBNumber
- CB7452079
- Molecular Formula
- C5H7NO2
- Formula Weight
- 113.11
- MOL File
- 35166-33-7.mol
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(5-Methylisoxazol-3-yl)methanol Property
- Boiling point:
- 64°C (0.2 mmHg)
- Density
- 1.46
- storage temp.
- 2-8°C
- form
- Liquid
- pka
- 13.12±0.10(Predicted)
- color
- Colorless
- CAS DataBase Reference
- 35166-33-7(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36/37/39-26
- HazardClass
- IRRITANT
- HS Code
- 29349990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- L482684
- Product name
- (5-METHYL-3-ISOXAZOLYL)METHANOL
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $185
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- L482684
- Product name
- (5-METHYL-3-ISOXAZOLYL)METHANOL
- Purity
- Aldrich
- Packaging
- 250mg
- Price
- $179
- Updated
- 2024/03/01
TRC
- Product number
- M315043
- Product name
- (5-Methylisoxazol-3-yl)methanol
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
TRC
- Product number
- M315043
- Product name
- (5-Methylisoxazol-3-yl)methanol
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
Oakwood
- Product number
- 017477
- Product name
- 3-Hydroxymethyl-5-methylisoxazole
- Purity
- 98%
- Packaging
- 100mg
- Price
- $20
- Updated
- 2021/12/16
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(5-Methylisoxazol-3-yl)methanol Chemical Properties,Usage,Production
Chemical Properties
Colorless to light yellow liquid
Uses
3-Hydroxymethyl-5-methylisoxazole (5-Methylisoxazole-3-methanol) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1].
Synthesis
19788-35-3
35166-33-7
General procedure for the synthesis of (5-methylisoxazol-3-yl)methanol from methyl 5-methylisoxazole-3-carboxylate: Methyl 5-methylisoxazole-3-carboxylate (14.12 g, 100 mmol) was dissolved in anhydrous THF (150 mL) and cooled to -75 °C in a dry ice/isopropanol bath to form a white suspension. A THF solution of 1 M lithium aluminum hydride (105 mL, 105 mmol) was slowly added, and the rate of addition was controlled to maintain the internal temperature below -55 °C. The reaction mixture gradually turned yellow and was subsequently allowed to warm slowly to room temperature and stirred overnight. The reaction mixture was again cooled to -75 °C, cold water was carefully added until gas release ceased, and then the pH was adjusted to 1-2 with aqueous 6N HCl. The reaction mixture became viscous and was concentrated under reduced pressure to remove the solvent. The residue was dissolved in toluene and azeotropized to remove water. After drying, the residue was washed with chloroform (3 x 100 mL), the chloroform solution was filtered to remove insoluble solids, and finally the solvent was evaporated to give the light yellow oily product (5-methylisoxazol-3-yl)methanol in a yield of 8.34 g (74% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 6.02 (s, 1H), 4.66 (s, 2H), 2.80-3.10 (m, 1H), 2.39 (s, 3H).
References
[1] Bergmeyer H U, et al. Biochemical reagents[M]//Methods of Enzymatic Analysis. Academic Press, 1965: 967-1037.
(5-Methylisoxazol-3-yl)methanol Preparation Products And Raw materials
Raw materials
Ethanol
Acetone
Diethyl oxalate
Sodium
Sodium borohydride
Ethyl acetate
Hydroxylamine hydrochloride
Sulfuric acid
Preparation Products
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View Lastest Price from (5-Methylisoxazol-3-yl)methanol manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- (5-Methylisoxazol-3-yl)methanol 35166-33-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-09
Career Henan Chemical Co
- Product
- (5-Methylisoxazol-3-yl)methanol 35166-33-7
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-22
35166-33-7, (5-Methylisoxazol-3-yl)methanolRelated Search:
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5-Methylisoxazole-3-carboxylic acid
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ISOFENPHOS-METHYL
ETHYL 5-METHYLISOXAZOLE-3-CARBOXYLATE
5-ETHYL-ISOXAZOLE-3,4-DICARBOXYLIC ACID DIETHYL ESTER
Methyl 5-methylisoxazole-3-carboxylate
5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID
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Oxazole
ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE
ETHYL 4-[(4-CHLOROANILINO)CARBONYL]-5-METHYL-3-ISOXAZOLECARBOXYLATE