3-Methoxy-4-nitrobenzoic acid
- Product Name
- 3-Methoxy-4-nitrobenzoic acid
- CAS No.
- 5081-36-7
- Chemical Name
- 3-Methoxy-4-nitrobenzoic acid
- Synonyms
- 4-Nitro-m-anisic acid;3-Methoxy-4-nitrobenzoic;3-Methoxy-4-nitrobenzoicaci;4-Nitro-3-methoxybenzoic acid;3-Methoxy-4-Mitrobenzoic Acid;3-METHOXY-4-NITROBENZOIC ACID;3-METHOXY-4-NITROBENZOIC ACIID;3-Methoxy-4-nitrobenzoicAcid>Benzoic acid, 3-methoxy-4-nitro-;3-METHOXY-4-NITROBENZOIC ACID, 98+%
- CBNumber
- CB7460614
- Molecular Formula
- C8H7NO5
- Formula Weight
- 197.14
- MOL File
- 5081-36-7.mol
3-Methoxy-4-nitrobenzoic acid Property
- Melting point:
- 233-235 °C (lit.)
- Boiling point:
- 334.23°C (rough estimate)
- Density
- 1.5023 (rough estimate)
- refractive index
- 1.5700 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 3.30±0.10(Predicted)
- color
- White to Light yellow to Light orange
- Water Solubility
- Insoluble in water.
- BRN
- 2696042
- InChI
- InChI=1S/C8H7NO5/c1-14-7-4-5(8(10)11)2-3-6(7)9(12)13/h2-4H,1H3,(H,10,11)
- InChIKey
- PWURRRRGLCVBMX-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC=C([N+]([O-])=O)C(OC)=C1
- CAS DataBase Reference
- 5081-36-7(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 184306
- Product name
- 3-Methoxy-4-nitrobenzoic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $62
- Updated
- 2023/06/20
- Product number
- M2083
- Product name
- 3-Methoxy-4-nitrobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $35
- Updated
- 2025/07/31
- Product number
- M2083
- Product name
- 3-Methoxy-4-nitrobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $138
- Updated
- 2025/07/31
- Product number
- M326963
- Product name
- 3-Methoxy-4-nitrobenzoic Acid
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 281615
- Product name
- 3-Methoxy-4-nitrobenzoic acid
- Packaging
- 100g
- Price
- $632
- Updated
- 2021/12/16
3-Methoxy-4-nitrobenzoic acid Chemical Properties,Usage,Production
Chemical Properties
light yellow to beige crystalline powder
Uses
3-Methoxy-4-nitrobenzoic acid was used in detection of nitroaromatic compounds by CdSe- quantum dots capped with polyamidoamine dendrimer-1,12-diaminododecane core-generation 4 nanocomposites. It was used in the synthesis of vorozole derivatives.
Synthesis
5081-37-8
5081-36-7
The general procedure for the synthesis of 3-methoxy-4-nitrobenzoic acid from methyl 3-methoxy-4-nitrobenzoate was as follows: to a stirred solution of methyl 3-methoxy-4-nitrobenzoate (2.11 g, 10 mmol) in methanol (30 mL), a solution of potassium hydroxide (1.68 g, 30 mmol) in water (30 mL) was added. The reaction mixture was refluxed for 2 hours and subsequently the methanol was removed by vacuum distillation. The residue was diluted with distilled water (20 mL) and cooled in an ice bath. It was acidified with saturated aqueous potassium bisulfate to pH 3-4. The precipitated solid was collected by filtration and washed sequentially with cold water and hexane. The product was an off-white solid in 96% yield, mass spectrum (ESI+) m/z 198 [M + H]+.
References
[1] Patent: US2016/145304, 2016, A1. Location in patent: Paragraph 0548; 0562; 0563; 0564
[2] ChemMedChem, 2018, vol. 13, # 2, p. 186 - 198
[3] Journal of the American Chemical Society, 1989, vol. 111, # 20, p. 7957 - 7968
[4] eLife, 2017, vol. 6,
[5] Advanced Synthesis and Catalysis, 2018, vol. 360, # 11, p. 2204 - 2210
3-Methoxy-4-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Methoxy-4-nitrobenzoic acid Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
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- Country
- Europe
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- Advantage
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View Lastest Price from 3-Methoxy-4-nitrobenzoic acid manufacturers
- Product
- 3-Methoxy-4-nitrobenzoic acid 5081-36-7
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-25
- Product
- 3-Methoxy-4-nitrobenzoic acid 5081-36-7
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-18