ChemicalBook > CAS DataBase List > AZD-0284

AZD-0284

Product Name: AZD-0284
CAS No.: 2101291-07-8
Chemical Name: AZD-0284
Synonyms: AZD-0284;AZD-0284, 10 mM in DMSO;(R)-2-Acetyl-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-5-(methylsulfonyl)isoindoline-1-carboxamide; (1R)-2-acetyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-5-methanesulfonyl-2,3-dihydro-1H-isoindole-1-carboxamide;1H-Isoindole-1-carboxamide, 2-acetyl-2,3-dihydro-5-(methylsulfonyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, (1R)-;tract,RAR-related orphan receptor,IL-17F,L-23R,Inhibitor,AZD-0284,plaque,respiratory,vulgaris,production,IL-17A,TH17,psoriasis,IL-22,AZD 0284,inhibit,cells,ROR,AZD0284
CBNumber: CB74667590
Molecular Formula: C21H18F6N2O5S
Formula Weight: 524.43
MOL File: 2101291-07-8.mol

Less

AZD-0284 Property

Boiling point:: 731.9±60.0 °C(Predicted)
Density: 1.534±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 100 mg/mL (190.68 mM)
form: Solid
pka: 9.26±0.15(Predicted)
color: White to off-white

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0077736
Product name: AZD-0284
Purity: 99.92%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0077736
Product name: AZD-0284
Purity: 99.92%
Packaging: 10mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-0077736
Product name: AZD-0284
Purity: 99.92%
Packaging: 50mg
Price: $2250
Updated: 2021/12/16

ChemScene

Product number: CS-0077736
Product name: AZD-0284
Purity: 99.92%
Packaging: 100mg
Price: $3350
Updated: 2021/12/16

Less

AZD-0284 Chemical Properties,Usage,Production

Uses

AZD-0284 is a selective inverse agonist of the nuclear receptor RORγ. AZD-0284 has the potential for plaque psoriasis vulgaris and respiratory tract disorders treatment[1].

References

[1] Narjes, F, et al. The discovery of AZD0284, an inverse agonist of the nuclear receptor RORg. American Chemical Society, 2017 Drug Design and Delivery Symposium 26 October 2017
[2] Asimus S, et al. Pharmacokinetics, pharmacodynamics and safety of the inverse retinoic acid-related orphan receptor γ agonist AZD0284 [published online ahead of print, 2020 Feb 17]. Br J Clin Pharmacol. 2020;10.1111/bcp.14253. DOI:10.1111/bcp.14253

AZD-0284 Preparation Products And Raw materials

Raw materials

Preparation Products

Less

AZD-0284 Suppliers

China 43 United States 4 Global 47

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
Advantage: 58

Shanghai XingMo Biotechnology Co., Ltd.

Tel: +86 13524779951; 13524779951
Fax: QQ: 2075692521
Email: 2075692521@qq.com
Country: China
ProdList: 301
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Shanghai Yihe Biological Technology Co., Ltd.

Tel: 021-68882955 17721395025
Fax: 021-68882955
Email: 2423903095@qq.com
Country: China
ProdList: 4992
Advantage: 58

Kaixin Chemical (Hong Kong) Limited

Tel: 010-88886666-01 13112345678
Fax: CDXH21@126.com
Email: loyson@tcypharm.com
Country: China
ProdList: 597
Advantage: 55

Shanghai Maruhua Science and Technology Co. Ltd.

Tel: 021-57171708 18721745940
Fax: QQ1139783351
Email: sales@api-chem.com
Country: China
ProdList: 1968
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Henan Lien Chemical Products Co., Ltd.

Tel: 03716091-9097 13383857418
Fax: 03716091-9097
Email: 1520689222@qq.com
Country: China
ProdList: 4863
Advantage: 58

Henan Weituxi Chemical Technology Co., Ltd.

Tel: 0371-63284658 18135795563
Fax: QQ:2885349392
Email: 2885349392@qq.com
Country: China
ProdList: 9992
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd

Tel: 15317229551
Fax: QQ:3607245178
Email: 15151849396@163.com
Country: China
ProdList: 989
Advantage: 58

Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15727060112
Email: yutianchun2007@126.com
Country: China
ProdList: 9814
Advantage: 58

Beijing krre Technology Co., Ltd

Tel: 17710868586
Email: 991087253@qq.com
Country: China
ProdList: 473
Advantage: 58

Nantong Hi-Future Biotechnology Co., Ltd

Tel: 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 2998
Advantage: 58

Tianjin Xinghan Biotechnology Co., Ltd

Tel: 13230698506 18698089028
Email: 1725517238@qq.com
Country: China
ProdList: 5009
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Suzhou Haiben Pharmaceutical Co., Ltd

Tel: 19353112242
Email: 1816280386@qq.com
Country: China
ProdList: 8045
Advantage: 58

Tianjin Zhennuo Pharmaceutical Group Co., Ltd

Tel: 15620629054
Email: ivyding@medhonor.com.cn
Country: China
ProdList: 64
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12000
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Tianjin Xinkangyou Biotechnology Co., LTD

Tel: 19922659386
Email: niuli@tjxkys.cn
Country: China
ProdList: 2995
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9835
Advantage: 58

Anhui JYHX CO., LTD.

Tel: 0551-68788198 13295518198
Email: wangyanan@ahjyhx.com
Country: China
ProdList: 1759
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd

Tel: 025-58851090 17714375163
Email: 2881759498@qq.com
Country: China
ProdList: 13011
Advantage: 58

Shaanxi Gulliver Biotechnology Research Co., Ltd

Tel: 0917-77953337 18409274651
Email: 2823986536@qq.com
Country: China
ProdList: 2963
Advantage: 58

Shandong Dongde New Materials Co., Ltd

Tel: 13290191024
Email: 3887351301@qq.com
Country: China
ProdList: 1910
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
Advantage: 58

Selleck Chemicals

Tel: 400-668-6834
Email: info@selleck.cn
Country: China
ProdList: 6071
Advantage: 58

Tianjin Xinghan Biotechnology Co., Ltd

Tel: +8618698089028
Email: 1725517238@qq.com
Country: China
ProdList: 2479
Advantage: 58

Nantong HI-FUTURE Biology Co., Ltd.

Tel: +undefined18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 3135
Advantage: 58

Guangzhou Yansai Biological Products Co., Ltd.

Tel: 13710209565
Country: CHINA
ProdList: 122
Advantage: 58

Guangzhou Jingyan Biotechnology Co., Ltd.

Tel: 13822277471
Country: CHINA
ProdList: 187
Advantage: 58

Guangzhou Suyan Biotechnology Co., Ltd

Tel: 18818417021
Country: CHINA
ProdList: 127
Advantage: 58

Biorbyt Ltd.

Tel: --
Fax: --
Email: info@biorbyt.com
Country: CHINA
ProdList: 6482
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

Guangzhou Weijia Technology Co., Ltd.

Tel: --
Fax: --
Email: WHIGA22@126.COM
Country: CHINA
ProdList: 6757
Advantage: 58

Shanghai Qiming Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6502
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

2101291-07-8, AZD-0284Related Search:

AZD-5672 AZD0364 CCR1 antagonist AZD-7648 AZD5153 AZD-8055 AZD-5305 AZD 3759 2-Pyridinecarboxamide, 6-fluoro-5-[4-[(5-fluoro-3,4-dihydro-2-methyl-3-oxo-6-quinoxalinyl)methyl]-1-piperazinyl]-N-methyl- AZD3839 hemifuMarate KGZHRAVDXGQUQM-WCQGTBRESA-N (S)-1-(2-(difluoromethyl)pyridin-4-yl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine AZD-2858 AZD-0156

AZD-0284

1H-Isoindole-1-carboxamide, 2-acetyl-2,3-dihydro-5-(methylsulfonyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, (1R)-

(1R)-2-acetyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-5-methanesulfonyl-2,3-dihydro-1H-isoindole-1-carboxamide

tract,RAR-related orphan receptor,IL-17F,L-23R,Inhibitor,AZD-0284,plaque,respiratory,vulgaris,production,IL-17A,TH17,psoriasis,IL-22,AZD 0284,inhibit,cells,ROR,AZD0284

(R)-2-Acetyl-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-5-(methylsulfonyl)isoindoline-1-carboxamide

AZD-0284, 10 mM in DMSO

2101291-07-8

C21H18F6N2O5S