m-PEG4-DBCO

Product Name: m-PEG4-DBCO
CAS No.: 2228857-36-9
Chemical Name: m-PEG4-DBCO
Synonyms: m-PEG4-DBCO;m-PEG4-NH-DBCO;mPEG4-DBCO,mPEG4-ADIBO,mPEG4-Dibenzocycolctyne
CBNumber: CB74849622
Molecular Formula: C28H34N2O6
Formula Weight: 494.59
MOL File: 2228857-36-9.mol

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m-PEG4-DBCO Property

Boiling point:: 746.8±60.0 °C(Predicted)
Density: 1.21±0.1 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
pka: 15.14±0.46(Predicted)
form: Liquid
color: Light yellow to yellow
InChI: InChI=1S/C28H34N2O6/c1-33-16-17-35-20-21-36-19-18-34-15-14-29-27(31)12-13-28(32)30-22-25-8-3-2-6-23(25)10-11-24-7-4-5-9-26(24)30/h2-9H,12-22H2,1H3,(H,29,31)
InChIKey: CUEOILOXVJZHLK-UHFFFAOYSA-N
SMILES: C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCC(=O)NCCOCCOCCOCCOC

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24030
Product name: m-PEG4-DBCO
Purity: 98%
Packaging: 250mg
Price: $650
Updated: 2021/12/16

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m-PEG4-DBCO Chemical Properties,Usage,Production

Description

m-PEG4-DBCO is a click chemistry reagents which can enable so called copper-free Click Chemistry with azide to form a stable triazole.

Uses

m-PEG4-NH-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG4-NH-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

m-PEG4-DBCO Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG4-DBCO Suppliers

China 25 United States 4 Global 29

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
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Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 13892832556
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Country: China
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Henan Lien Chemical Products Co., Ltd.

Tel: 0371-63357898 15378766539
Email: 535046669@qq.com
Country: China
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Shanghai Minhan Pharmaceutical Technology Co., Ltd.

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Guangzhou Younan Technology Co., Ltd

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Email: YN_research@163.com
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Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
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Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9947
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View Lastest Price from m-PEG4-DBCO manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: m-PEG4-DBCO 2228857-36-9
Price: US $0.00/mg
Min. Order: 50mg
Purity: >97.00%
Supply Ability: 250mg
Release date: 2024-03-20

2228857-36-9, m-PEG4-DBCORelated Search:

3,6,9,12,15-Pentaoxahexadecane-1-thiol MPEG11-CH2CH2COONHS 13-Azido-2,5,8,11-tetraoxa-tridecane PENTAETHYLENE GLYCOL MONOMETHYL ETHER 1-{2-[2-(2-{2-[2-(2-Bromo-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-2-methoxy-ethane m-PEG3-Tos m-PEG11-acid Hexaethylene Glycol Monomethyl Ether 2,5,8,11-TETRAOXATRIDECANE-13-THIOL 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane m-PEG9-bromide MPEG11-CH2CH2COOH MPEG7-CH2CH2COOH m-PEG2-Azide m-PEG6-bromide 2-[2-(2-methoxyethoxy)ethoxy]ethylamine mPEG3-CH2COOH 2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate

m-PEG4-DBCO

mPEG4-DBCO,mPEG4-ADIBO,mPEG4-Dibenzocycolctyne

m-PEG4-NH-DBCO

2228857-36-9