m-PEG4-DBCO
- Product Name
- m-PEG4-DBCO
- CAS No.
- 2228857-36-9
- Chemical Name
- m-PEG4-DBCO
- Synonyms
- m-PEG4-DBCO;m-PEG4-NH-DBCO;mPEG4-DBCO,mPEG4-ADIBO,mPEG4-Dibenzocycolctyne
- CBNumber
- CB74849622
- Molecular Formula
- C28H34N2O6
- Formula Weight
- 494.59
- MOL File
- 2228857-36-9.mol
m-PEG4-DBCO Property
- Boiling point:
- 746.8±60.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- pka
- 15.14±0.46(Predicted)
- form
- Liquid
- color
- Light yellow to yellow
- InChI
- InChI=1S/C28H34N2O6/c1-33-16-17-35-20-21-36-19-18-34-15-14-29-27(31)12-13-28(32)30-22-25-8-3-2-6-23(25)10-11-24-7-4-5-9-26(24)30/h2-9H,12-22H2,1H3,(H,29,31)
- InChIKey
- CUEOILOXVJZHLK-UHFFFAOYSA-N
- SMILES
- C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCC(=O)NCCOCCOCCOCCOC
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-24030
- Product name
- m-PEG4-DBCO
- Purity
- 98%
- Packaging
- 250mg
- Price
- $650
- Updated
- 2021/12/16
m-PEG4-DBCO Chemical Properties,Usage,Production
Description
m-PEG4-DBCO is a click chemistry reagents which can enable so called copper-free Click Chemistry with azide to form a stable triazole.
Uses
m-PEG4-NH-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG4-NH-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
m-PEG4-DBCO Preparation Products And Raw materials
Raw materials
Preparation Products
m-PEG4-DBCO Suppliers
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View Lastest Price from m-PEG4-DBCO manufacturers
- Product
- m-PEG4-DBCO 2228857-36-9
- Price
- US $0.00/mg
- Min. Order
- 50mg
- Purity
- >97.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-20