ChemicalBook > CAS DataBase List > MES monohydrate

MES monohydrate

Product Name
MES monohydrate
CAS No.
145224-94-8
Chemical Name
MES monohydrate
Synonyms
MES HYDRATE;MES.H2O;MORPHOLINOETHANE SULFONIC ACID MONOHYDRATE;2-(N-MORPHOLINO)ETHANESULFONIC ACID HYDRATE;4-MORPHOLINEETHANESULFONIC ACID MONOHYDRATE;MES-H;MES-HO;MES)MES Monohyd;MES MONOHYDRATE;MES monohydrate,MES
CBNumber
CB7485620
Molecular Formula
C6H15NO5S
Formula Weight
213.25
MOL File
145224-94-8.mol
More
Less

MES monohydrate Property

Melting point:
>300 °C(lit.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: 0.5 M at 20 °C, clear
form 
Powder, Crystals or Flakes
color 
White to pale yellow and/or orange
PH Range
5.5 - 6.7
Odor
Odorless
PH
2.5-4.0 (25℃, 0.5M in H2O)
pka
6.1(at 25℃)
Water Solubility 
Soluble in water.
λmax
λ: 260 nm Amax: 0.025
λ: 280 nm Amax: 0.020
Merck 
14,5902
BRN 
141319
InChI
InChI=1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2
InChIKey
MIIIXQJBDGSIKL-UHFFFAOYSA-N
SMILES
S(=O)(=O)(O)CCN1CCOCC1.O
CAS DataBase Reference
145224-94-8(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
QE3479500
TSCA 
Yes
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
69889
Product name
MES monohydrate
Purity
BioUltra, for molecular biology, ≥99.5% (T)
Packaging
10g
Price
$97.4
Updated
2024/03/01
Sigma-Aldrich
Product number
69889
Product name
MES monohydrate
Purity
BioUltra, for molecular biology, ≥99.5% (T)
Packaging
50g
Price
$309
Updated
2024/03/01
Sigma-Aldrich
Product number
RES0113M-A7
Product name
MES monohydrate
Purity
PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture
Packaging
1pkg
Price
$3045
Updated
2022/05/15
Alfa Aesar
Product number
A16104
Product name
MES monohydrate, 98%
Packaging
25g
Price
$46.2
Updated
2024/03/01
Alfa Aesar
Product number
A16104
Product name
MES monohydrate, 98%
Packaging
100g
Price
$109
Updated
2024/03/01
More
Less

MES monohydrate Chemical Properties,Usage,Production

Description

MES Monohydrate is a zwitterionic buffer that is not absorbed through cell membranes and is virtually transparent in UV light. MES is a buffering agent used in many biological and biochemical applications. It is also used as a running buffer for denaturing gel electrophoresis. The characteristics of low UV absorptivity, minimal reactivity, stable pH and solubility in water allow MES Monohydrate to be used as a Good's buffer.

Chemical Properties

white crystalline powder

Uses

MES Monohydrate has been used:

  • To adjust the pH of growth medium to 5.5-7.0 in an in vitro cell wall stress assay
  • As a buffering agent to stabilize enzymatic solutions
  • As a component of PAGE running buffer

Uses

MES monohydrate is a biological buffer often referred to as Good?s buffer. It is useful for cell culture media and protein based buffer formulations to maintain a stable environment in solution. It is also used in the purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors. It is a useful resolving agent for very small proteins on bis-tris gels. Buffer solutions are used as a means of keeping pH at a nearly constant value in a wide variety of chemical applications.

Uses

MES monohydrate is a buffering agent used in biochemistry and molecular biology that was selected and described by Good et al. It is a zwitterionic, morpholinic buffer that is useful for a pH range of 5.5 – 6.7 and commonly used for cell culture media, as a running buffer in electrophoresis, and for protein purification in chromatography. MES lacks the ability to form a complex with most metal ions and is recommended for use as a non-coordinating buffer in solutions with metal ions. MES is often used in buffered culture media for bacteria, yeast, and mammalian cells. It is toxic towards plants at high concentrations, but can be used in culture media at lower concentrations for plants. Due to low ionic mobility, MES is regarded as an excellent buffer for use in capillary electrochromatography. MES is often employed as a substitute for the highly toxic cacodylate, as well as a substitute for the non-zwitterionic buffers citrate and malate. MES complexes with some organotin(IV) molecules that are being explored as antitumor agents.
MES free acid or MES free acid monohydrate can be mixed with MES sodium salt to acquire desired pH. Alternatively, MES free acid or MES free acid monohydrate can be titrated with sodium hydroxide to attain desired pH.

Application

MES is one of the "Good" buffers developed for biological applications. MES is not recommended at pH 7.4; other buffers should be considered. All qualities are tested for trace ions and all can be used for biological and biochemistry applications. This product is used in biochemical and biological techniques where highly purified products are needed.
MES Monohydrate has been used:
To adjust the pH of growth medium to 5.5-7.0 in an in vitro cell wall stress assay.
As a buffering agent to stabilize enzymatic solutions.
As a component of PAGE running buffer.

General Description

buffer substance MES

Preparation and handling

A buffer using MES free acid can be prepared by titrating the free acid with sodium hydroxide to the desired pH (pKa =±1). Alternatively, volumes of equimolar MES free acid and sodium MES can be mixed to attain the desired pH. Standard mixing tables using stock solutions to prepare a buffer of a given pH have been published.

Precautions

Solubility/Stability: MES is soluble in water, giving a clear colourless solution at concentrations of 0.5M or higher. The pH of a solution should be between 2.5 and 5, depending on the concentration. Solutions are stable at 2-8°C for months.
Sterilization: Sterilization should be by filteration through 0.2μM filters. Autoclaving is not recommended by any sulfonic acid buffers. If buffers must be nuclease-free, it is best to treat the water, then add the buffer solids after autoclaving. When MES solutions are autoclaved, they turn yellow (although pH does not change measurably. The identity of the yellow breakdown product is unkown.

MES monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

MES monohydrate Suppliers

Nanjing Search Biotech Co., Ltd
Tel
+86-025-81682922 +86-13515111588
Fax
025-85860962
Email
sales@searchbio.com.cn
Country
China
ProdList
135
Advantage
68
AILY INTL CHEMICAL CORP LTD
Tel
025-83208295 18913388297
Fax
+86-2583208202
Email
ben@ailychem.com
Country
China
ProdList
132
Advantage
50
Hunan Hengfei bio-pharmaceutical Co. , Ltd.
Tel
0746-6222194 13874779848
Fax
0746-6222194
Email
57182844@qq.com
Country
China
ProdList
96
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 13451648594
Fax
0512-87182056
Email
sales@yacoo.com.cn
Country
China
ProdList
4578
Advantage
58
Suzhou Genemill Biotechnology Co.,Ltd
Tel
0512-65917170 17766001019;
Email
xiely@genemill.com
Country
China
ProdList
36
Advantage
58
WuHan Difu Biotechnology Co.Ltd
Tel
18008681304
Email
898948847@qq.com
Country
China
ProdList
100
Advantage
58
Hubei xinghengkang Chemical Technology Co., Ltd
Tel
027-88878869 18162384755
Email
969094702@qq.com
Country
China
ProdList
59
Advantage
58
Shanghai CanSpecsci Instrument Co., Ltd.
Tel
400-6087598 15021221957
Fax
4006087598-8012
Email
order@canspecsci.com
Country
China
ProdList
2045
Advantage
56
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
Advantage
57
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4554
Advantage
62
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2866
Advantage
58
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Suzhou BEC Biological Technology Co., Ltd
Tel
+86-512-68095917 13862064516
Fax
+86-512-68417933
Email
sales@bek.com.cn
Country
China
ProdList
146
Advantage
59
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-84699383-8003 18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
971
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3921
Advantage
50
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3583
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3991
Advantage
60
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
0371-13526885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3978
Advantage
58
Suzhou Laing Biological Technology Co., LTD
Tel
0512-62968256 18550502935
Fax
0512-62968256
Email
export@laingbiotec.com
Country
China
ProdList
1113
Advantage
58
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6773
Advantage
55
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11578
Advantage
59
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5800
Advantage
50
More
Less

View Lastest Price from MES monohydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
MES monohydrate 145224-94-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
3500kg/month
Release date
2021-09-09
Hebei Yanxi Chemical Co., Ltd.
Product
MES monohydrate 145224-94-8
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-14
Hebei Weibang Biotechnology Co., Ltd
Product
MES monohydrate 145224-94-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25

145224-94-8, MES monohydrateRelated Search:


  • 2-(4-morpholinyl)ethanesulfonic acid hydrate
  • MES monohydrate, ≥99% (T)
  • 2-(N-MORPHOLINO)ETHANESULFONIC ACID, MONOHYDRATE2-(N-MORPHOLINO)ETHANESULFONIC ACID, MONOHYDRATE2-(N-MORPHOLINO)ETHANESULFONIC ACID, MONOHYDRATE2-(N-MORPHOLINO)ETHANESULFONIC ACID, MONOHYDRATE
  • MES 1HYD FREE ACID XTL
  • MES FREE ACID MONOHYDRATE ULTRA PURE GRADE 99+% 2-MORPHOLINOETHANESULFONIC ACID
  • Mes-H2-(N-Morpholino)EthanesulfonicAcidMonohydrate
  • MesBuffer,Monohydrate
  • MESH2OMESmonohydrate
  • MES monohydrate, for biochemistry, 99+%
  • Morpholine-4-ethanesulfonic acid hydrate
  • MES MONOHYDRATE IN FOIL POUCHES, BIOTECH
  • 2-(N-MORPHOLINO)ETHANESULFONICACID1-HYDRATE
  • MES MONOHYDRATE ULTRAPURE
  • 2-(N-Morpholino)ethanesulphonic acid monohydrate
  • MES-H
  • 2-(4-morpholino)ethanesulfonic acid hydrate
  • 2-Morpholinoethanesulfonic acid hydrate
  • MES)MES Monohyd
  • Morpholinoethane sulfonic acid, Monohydrate analytical grade
  • AwaterMorpholinoethane sulfonic acid
  • MES monohydrate Vetec(TM) reagent grade, 99%
  • EZNA MICROELUTE DNA CLEAN-UP KIT
  • MES, free acid, monohydrate
  • KIT MICROELUTE DNA CLEAN-UP EZNA 5 TESTS
  • MES MONOHYDRATE BIOXTRA, >= 99.0% (&
  • MES-HO
  • 2-(N-MORPHOLINO)ETHANESULFONIC ACID MONOHYDRATE;4-MORPHOLINEETHANESULFONIC ACID MONOHYDRATE
  • MES.H2O
  • MES monohydrate,2-(N-Morpholino)ethanesulfonic acid, 4-Morpholineethanesulfonic acid monohydrate
  • MES monohydrate (2-Morpholinoethan sulfonic acid)
  • MES Monohydrate ,99%
  • 2-(N-Morpholino)ethanesulfonic acid monohydrate ,99%
  • MES, Monohydrate, Biological Buffer
  • 2-MORPHOLINOETHANESULPHONIC ACID extrapure
  • 2-(N-Morpholino)ethanesulfonic acid, 4-Morpholineethanesulfonic acid monohydrate
  • MES monohydrate, for biochemistry
  • MES, 2-(N-Morpholino)ethanesulfonic acid monohydrate
  • MES monohydrate,99+%,for biochemistry
  • 2-(N-MORPHOLINO)ETHANESULFONIC ACID HYDRATE
  • 2-(N-MORPHOLINO)ETHANESULFONIC ACID, MONOHYDRATE
  • 2-MORPHOLINOETHANESULFONIC ACID MONOHYDRATE
  • MORPHOLINOETHANE SULFONIC ACID MONOHYDRATE
  • MES MONOHYDRATE
  • MES HYDRATE
  • 4-MORPHOLINEETHANESULFONIC ACID MONOHYDRATE
  • 4-MORPHOLINOETHANESULFONIC ACID HYDRATE
  • MES Monohydrate, for biocheMistry, 99+% 100GR
  • MES monohydrate Buffer salt
  • 2-(N-Morpholino)ethanesulfonic acid monohydrate, 99%, reagent grade
  • 2-morpholin-4-ylethanesulfonicacid,hydrate
  • 4-Morpholineethanesulfonic acid, hydrate (1:1)
  • 2-Morpholinoethanesulphonic acid hydrate AR (MES)
  • Morpholino ethane sulphonic acid, monohydrate, 99%
  • 2-(N-Morpholino)Ethane-Sulfonic Acid, Extra Pure, SLR, Fisher Chemical
  • MES Monohydrate Buffer extrapure, 99%
  • MES Monohydrate Buffer for cell culture, 99%, Endotoxin (BET) 0.05EU/mg
  • MES Monohydrate Buffer for molecular biology, 99%
  • MES Monohydrate Buffer for tissue culture, 99%