ChemicalBook > CAS DataBase List > (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE

(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE

Product Name: (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
CAS No.: 150145-89-4
Chemical Name: (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
Synonyms: (S)-MCPG;(+)-MCPG;(S)MCPG,(S) MCPG;(alphaS)-alpha-Amino-4-Carbo;(+)-α-methyl-4-carboxyphenylglycine;(S)-α-Methyl-4-carboxyphenylglycine;(S)-ALFA-METHYL-4-CARBOXYPHENYLGLYCINE;(S)-MCPG, Group I / II mGlu antagonist;(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE;(+)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
CBNumber: CB7485802
Molecular Formula: C10H11NO4
Formula Weight: 209.2
MOL File: 150145-89-4.mol

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(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE Property

Boiling point:: 425.3±40.0 °C(Predicted)
Density: 1.390±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: 0.1 M NaOH: 15 mg/mL
form: solid
pka: 1.76±0.10(Predicted)
color: White to off-white
optical activity: [α]20/D +89.54°, c = 0.33 in 6 M HCl(lit.)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29224985

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M196
Product name: (+)-α-Methyl-4-carboxyphenylglycine
Purity: solid
Packaging: 5mg
Price: $268
Updated: 2025/07/31

Cayman Chemical

Product number: 21450
Product name: (S)-MCPG
Purity: ≥98%
Packaging: 5mg
Price: $66
Updated: 2024/03/01

Cayman Chemical

Product number: 21450
Product name: (S)-MCPG
Purity: ≥98%
Packaging: 10mg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 21450
Product name: (S)-MCPG
Purity: ≥98%
Packaging: 25mg
Price: $275
Updated: 2024/03/01

Tocris

Product number: 0337
Product name: (S)-MCPG
Purity: ≥99%(HPLC)
Packaging: 10
Price: $294
Updated: 2021/12/16

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(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE Chemical Properties,Usage,Production

Chemical Properties

white to off-white solid

Uses

Active enantiomer of (±)-MCPG

Definition

ChEBI: (S)-alpha-methyl-4-carboxyphenylglycine is a non-proteinogenic alpha-amino acid that is alanine in which the alpha-hydrogen is replaced by a 4-carboxyphenyl group (the S-enantiomer). It is a non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. It has a role as a metabotropic glutamate receptor antagonist.

Biological Activity

Active isomer of (RS)-MCPG ((RS)-a-Methyl-4-carboxyphenylglycine ). Non-selective group I/group II metabotropic glutamate receptor antagonist. Also available as part of the Group I mGlu Receptor Tocriset™ , Group II mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™ .

Biochem/physiol Actions

(+)-α-Methyl-4-carboxyphenylglycine, also known as MCPG, is a competitive metabotropic glutamate receptor antagonist.

storage

Room temperature

(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE Suppliers

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150145-89-4, (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINERelated Search:

(RS)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE 4-(2-hydroxyethyl)benzoic acid 2-AMINO-2-PHENYLPROPIONIC ACID (S)-(-)-1-(P-TOLYL)ETHYLAMINE 1-(4-METHYLPHENYL)ETHYLAMINE 96 2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID 4-CARBOXYPHENYLACETIC ACID (R)-(+)-1-(4-Methoxyphenyl)ethylamine 4-(HYDROXYMETHYL)PHENYLACETIC ACID Benzenemethanol, 4-[(1R)-1-aminoethyl]- 4-(1-AMINO-ETHYL)-BENZOIC ACID (RS)-4-CARBOXYPHENYLGLYCINE (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID 1-(4-METHYLPHENYL)-1-METHYLETHYLAMINE (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE (S)-4-(1-AMINOETHYL)BENZOIC ACID (S)-4-CARBOXYPHENYLGLYCINE (2S)-2-AMINO-2-PHENYLPROPANOIC ACID

(S)-MCPG

S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID

(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE

4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID

(+)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE

(S)-ALFA-METHYL-4-CARBOXYPHENYLGLYCINE

(S)-alpha-Methyl-4-carboxyphenylglycine(S)-MCPG

(+)-MCPG

(+-)-A-METHYL-4-CARBOXYPHENYLGLYCINE GLU TAMATE RECEPTOR AN

(+)-α-methyl-4-carboxyphenylglycine

(+)-MCPG, LY367385, S(+)-α-Amino-4-carboxy-α-methyl-benzeneacetic acid

4-[(1S)-1-Ammonio-1-Methyl-2-Oxido-2-Oxoethyl]Benzoate

4-[(1S)-1-Ammonio-2-Keto-1-Methyl-2-Oxido-Ethyl]Benzoate

4-[(1S)-1-Azaniumyl-1-Methyl-2-Oxido-2-Oxo-Ethyl]Benzoate

(alphaS)-alpha-Amino-4-Carboxy-alpha-Methyl-Benzeneacetic Acid

Benzeneacetic acid, α-amino-4-carboxy-α-methyl-, (αS)-

(S)-α-Methyl-4-carboxyphenylglycine

S(+)-α-Amino-4-carboxy-α-methyl-benzeneacetic acid

(alphaS)-alpha-Amino-4-Carbo

(S)MCPG,(S) MCPG

(S)-MCPG, Group I / II mGlu antagonist

150145-89-4

Glutamate receptor

Glutamate