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(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE

Product Name
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
CAS No.
150145-89-4
Chemical Name
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
Synonyms
(S)-MCPG;(+)-MCPG;(+)-MCPG;(S)MCPG,(S) MCPG;(alphaS)-alpha-Amino-4-Carbo;(+)-α-methyl-4-carboxyphenylglycine;(S)-α-Methyl-4-carboxyphenylglycine;(S)-ALFA-METHYL-4-CARBOXYPHENYLGLYCINE;(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE;(+)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
CBNumber
CB7485802
Molecular Formula
C10H11NO4
Formula Weight
209.2
MOL File
150145-89-4.mol
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(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE Property

Boiling point:
425.3±40.0 °C(Predicted)
Density 
1.390±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
0.1 M NaOH: 15 mg/mL
form 
solid
pka
1.76±0.10(Predicted)
color 
White to off-white
optical activity
[α]20/D +89.54°, c = 0.33 in 6 M HCl(lit.)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29224985
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M196
Product name
(+)-α-Methyl-4-carboxyphenylglycine
Purity
solid
Packaging
5mg
Price
$306
Updated
2024/03/01
Cayman Chemical
Product number
21450
Product name
(S)-MCPG
Purity
≥98%
Packaging
5mg
Price
$66
Updated
2024/03/01
Cayman Chemical
Product number
21450
Product name
(S)-MCPG
Purity
≥98%
Packaging
10mg
Price
$117
Updated
2024/03/01
Cayman Chemical
Product number
21450
Product name
(S)-MCPG
Purity
≥98%
Packaging
25mg
Price
$275
Updated
2024/03/01
Tocris
Product number
0337
Product name
(S)-MCPG
Purity
≥99%(HPLC)
Packaging
10
Price
$294
Updated
2021/12/16
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(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE Chemical Properties,Usage,Production

Chemical Properties

white to off-white solid

Uses

Active enantiomer of (±)-MCPG

Definition

ChEBI: (S)-alpha-methyl-4-carboxyphenylglycine is a non-proteinogenic alpha-amino acid that is alanine in which the alpha-hydrogen is replaced by a 4-carboxyphenyl group (the S-enantiomer). It is a non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. It has a role as a metabotropic glutamate receptor antagonist.

Biological Activity

Active isomer of (RS)-MCPG ((RS)-a-Methyl-4-carboxyphenylglycine ). Non-selective group I/group II metabotropic glutamate receptor antagonist. Also available as part of the Group I mGlu Receptor Tocriset™ , Group II mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™ .

Biochem/physiol Actions

(+)-α-Methyl-4-carboxyphenylglycine, also known as MCPG, is a competitive metabotropic glutamate receptor antagonist.

storage

Room temperature

(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE Suppliers

Belgium 1 China 51 Europe 1 Germany 3 Japan 2 Switzerland 3 Ukraine 1 United Kingdom 3 United States 13 Global 78
BIOTREND GmbH
Tel
--
Fax
--
Email
jaeger@biotrend.com
Country
Germany
ProdList
249
Advantage
65
BIOTREND Chemicals AG
Tel
--
Fax
--
Email
info@biotrend.ch
Country
Germany
ProdList
1250
Advantage
62
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

150145-89-4, (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINERelated Search:

(RS)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE 4-(2-hydroxyethyl)benzoic acid 2-AMINO-2-PHENYLPROPIONIC ACID (S)-(-)-1-(P-TOLYL)ETHYLAMINE 1-(4-METHYLPHENYL)ETHYLAMINE 96 2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID 4-CARBOXYPHENYLACETIC ACID (R)-(+)-1-(4-Methoxyphenyl)ethylamine 4-(HYDROXYMETHYL)PHENYLACETIC ACID Benzenemethanol, 4-[(1R)-1-aminoethyl]- 4-(1-AMINO-ETHYL)-BENZOIC ACID (RS)-4-CARBOXYPHENYLGLYCINE (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID 1-(4-METHYLPHENYL)-1-METHYLETHYLAMINE (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE (S)-4-(1-AMINOETHYL)BENZOIC ACID (S)-4-CARBOXYPHENYLGLYCINE (2S)-2-AMINO-2-PHENYLPROPANOIC ACID

  • (S)-MCPG
  • S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID
  • (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
  • 4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID
  • (+)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
  • (S)-ALFA-METHYL-4-CARBOXYPHENYLGLYCINE
  • (S)-alpha-Methyl-4-carboxyphenylglycine(S)-MCPG
  • (+)-MCPG
  • (+-)-A-METHYL-4-CARBOXYPHENYLGLYCINE GLU TAMATE RECEPTOR AN
  • (+)-α-methyl-4-carboxyphenylglycine
  • (+)-MCPG, LY367385, S(+)-α-Amino-4-carboxy-α-methyl-benzeneacetic acid
  • 4-[(1S)-1-Ammonio-1-Methyl-2-Oxido-2-Oxoethyl]Benzoate
  • 4-[(1S)-1-Ammonio-2-Keto-1-Methyl-2-Oxido-Ethyl]Benzoate
  • 4-[(1S)-1-Azaniumyl-1-Methyl-2-Oxido-2-Oxo-Ethyl]Benzoate
  • (alphaS)-alpha-Amino-4-Carboxy-alpha-Methyl-Benzeneacetic Acid
  • Benzeneacetic acid, α-amino-4-carboxy-α-methyl-, (αS)-
  • (S)-α-Methyl-4-carboxyphenylglycine
  • S(+)-α-Amino-4-carboxy-α-methyl-benzeneacetic acid
  • (alphaS)-alpha-Amino-4-Carbo
  • Benzeneacetic acid, α-amino-4-carboxy-α-methyl-, (αS)-
  • (+)-MCPG
  • (S)MCPG,(S) MCPG
  • 150145-89-4
  • Glutamate receptor
  • Glutamate