ChemicalBook > CAS DataBase List > CD437

CD437

Product Name
CD437
CAS No.
125316-60-1
Chemical Name
CD437
Synonyms
CS-2691;ADAP-IME;Ro472077;Ro 472077;Ro-472077;CD 437/AHPN;AHPN;CD 437;CD-437;CD437;CD-437;CD 437;O-demethyladaparine;Adapalene IMpurity F
CBNumber
CB7503287
Molecular Formula
C27H26O3
Formula Weight
398.49
MOL File
125316-60-1.mol
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CD437 Property

Melting point:
271.6-276 °C
Boiling point:
595.0±50.0 °C(Predicted)
Density 
1.290
storage temp. 
-20°C
solubility 
DMSO: 26 mg/mL
form 
solid
pka
4.17±0.30(Predicted)
color 
yellow
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
QJ1975900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C5865
Product name
CD437
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$258
Updated
2024/03/01
Sigma-Aldrich
Product number
178496
Product name
Apoptosis Activator VI, CD437/AHPN
Packaging
5mg
Price
$208
Updated
2024/03/01
Cayman Chemical
Product number
71610
Product name
CD437
Purity
≥95%
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
71610
Product name
CD437
Purity
≥95%
Packaging
10mg
Price
$116
Updated
2024/03/01
Sigma-Aldrich
Product number
C5865
Product name
CD437
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$870
Updated
2024/03/01
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CD437 Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

An intermediate in the preparation of Adapalene derivatives.

Definition

ChEBI: A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)g mma and induces cell cycle arrest and apoptosis in various cancer cells.

Biological Activity

Synthetic retinoid that is an RAR γ -selective agonist. Displays RAR γ -dependent and -independent effects on differentiation and apoptosis.

Biochem/physiol Actions

CD437 is a retinoic acid receptor (RAR)γ-selective agonist, γ-selective retinoid; potent inducer of apoptosis.

storage

Store at -20°C

CD437 Preparation Products And Raw materials

Raw materials

Preparation Products

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CD437 Suppliers

Canada 1 China 90 Germany 1 India 4 Switzerland 2 United Kingdom 3 United States 16 Global 117
Shanghai Boyle Chemical Co., Ltd.
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View Lastest Price from CD437 manufacturers

Career Henan Chemical Co
Product
CD 437 125316-60-1
Price
US $1.00/g
Min. Order
1g
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-10

125316-60-1, CD437Related Search:

2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl Methyl 6-bromo-2-naphthoate o-AdaMantylanisole 1-Adamantanol 1-NITROADAMANTANE N,N-Dimethyl-1-adamantylamine Adapalene Mehtyl 6-[3-(1-adamanty)-4-methoxy phenyl]-2-naphthoate O-DESMETHYLCARVEDILOL Phenol, 4-(2-(4-((1-((4-fluorophenyl)methyl)-1H-benzimidazol-2-yl)amin o)-1-piperidinyl)ethyl)- O-desmethylangolensin 1-(4-Hydroxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide N-(3-bromo-4-oxocyclohexyl)acetamide O-Desmethyl Apremilast Glucuronide Sodium Salt O-Desmethyl-Asoprisnil O-Desmethyl-Asoprisnil-d4 2-(1-ADAMANTYL)-4-METHYLPHENOL CD437

  • 2-naphthalenecarboxylicacid,6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphen
  • 6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphenyl)-2-naphthalenecarboxylic
  • AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid
  • O-DesMethyl Adapalene
  • CD 437/AHPN
  • Adapalene IMpurity F
  • Apoptosis Activator VI, CD437/AHPN
  • ADAP-IME
  • 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid
  • CD437;CD-437;CD 437
  • CS-2691
  • O-Desmethyl Adapalene-13C6
  • Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem
  • AHPN;CD 437;CD-437
  • Apoptosis Activator VI
  • 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthoic Acid
  • 2-Naphthalenecarboxylic acid, 6-(4-hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-
  • 6-(3-(Adamantan-1-yl)-4-hydroxyphenyl)-2-naphthoic acid
  • inhibit,Retinoid X receptors,CD437,CD-437,CD 437,RAR/RXR,Inhibitor,Autophagy,Retinoic acid receptors
  • CD437/6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid
  • Ro 472077
  • Ro472077
  • Ro-472077
  • O-demethyladaparine
  • CD 437, RARgamma-selective agonist.
  • 125316-60-1
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals