CD437

ChemicalBook > CAS DataBase List > CD437

Product Name: CD437
CAS No.: 125316-60-1
Chemical Name: CD437
Synonyms: CS-2691;ADAP-IME;Ro472077;Ro 472077;Ro-472077;CD 437/AHPN;AHPN;CD 437;CD-437;CD437;CD-437;CD 437;Adapalene IMpurity F;O-DesMethyl Adapalene
CBNumber: CB7503287
Molecular Formula: C27H26O3
Formula Weight: 398.49
MOL File: 125316-60-1.mol

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CD437 Property

Melting point:: 271.6-276 °C
Boiling point:: 595.0±50.0 °C(Predicted)
Density: 1.290
storage temp.: -20°C
solubility: DMSO: 26 mg/mL
form: solid
pka: 4.17±0.30(Predicted)
color: yellow

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: QJ1975900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C5865
Product name: CD437
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $258
Updated: 2024/03/01

Sigma-Aldrich

Product number: 178496
Product name: Apoptosis Activator VI, CD437/AHPN
Packaging: 5mg
Price: $208
Updated: 2024/03/01

Cayman Chemical

Product number: 71610
Product name: CD437
Purity: ≥95%
Packaging: 5mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 71610
Product name: CD437
Purity: ≥95%
Packaging: 10mg
Price: $116
Updated: 2024/03/01

Sigma-Aldrich

Product number: C5865
Product name: CD437
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $870
Updated: 2024/03/01

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CD437 Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

An intermediate in the preparation of Adapalene derivatives.

Definition

ChEBI: A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)g mma and induces cell cycle arrest and apoptosis in various cancer cells.

Biological Activity

Synthetic retinoid that is an RAR γ -selective agonist. Displays RAR γ -dependent and -independent effects on differentiation and apoptosis.

Biochem/physiol Actions

CD437 is a retinoic acid receptor (RAR)γ-selective agonist, γ-selective retinoid; potent inducer of apoptosis.

storage

Store at -20°C

CD437 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from CD437 manufacturers

Career Henan Chemical Co

Product: CD 437 125316-60-1
Price: US $1.00/g
Min. Order: 1g
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-10

125316-60-1, CD437Related Search:

2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl Methyl 6-bromo-2-naphthoate o-AdaMantylanisole 1-Adamantanol 1-NITROADAMANTANE N,N-Dimethyl-1-adamantylamine Adapalene Mehtyl 6-[3-(1-adamanty)-4-methoxy phenyl]-2-naphthoate O-DESMETHYLCARVEDILOL Phenol, 4-(2-(4-((1-((4-fluorophenyl)methyl)-1H-benzimidazol-2-yl)amin o)-1-piperidinyl)ethyl)- O-desmethylangolensin 1-(4-Hydroxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide N-(3-bromo-4-oxocyclohexyl)acetamide O-Desmethyl Apremilast Glucuronide Sodium Salt O-Desmethyl-Asoprisnil O-Desmethyl-Asoprisnil-d4 2-(1-ADAMANTYL)-4-METHYLPHENOL CD437

2-naphthalenecarboxylicacid,6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphen

6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphenyl)-2-naphthalenecarboxylic

AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid

O-DesMethyl Adapalene

CD 437/AHPN

Adapalene IMpurity F

Apoptosis Activator VI, CD437/AHPN

ADAP-IME

6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid

CD437;CD-437;CD 437

CS-2691

O-Desmethyl Adapalene-13C6

Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem

AHPN;CD 437;CD-437

Apoptosis Activator VI

6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthoic Acid

2-Naphthalenecarboxylic acid, 6-(4-hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-

6-(3-(Adamantan-1-yl)-4-hydroxyphenyl)-2-naphthoic acid

inhibit,Retinoid X receptors,CD437,CD-437,CD 437,RAR/RXR,Inhibitor,Autophagy,Retinoic acid receptors

CD437/6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid

Ro 472077

Ro472077

Ro-472077

125316-60-1

Aromatics

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