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Methyl 6-bromo-2-naphthoate

Product Name
Methyl 6-bromo-2-naphthoate
CAS No.
33626-98-1
Chemical Name
Methyl 6-bromo-2-naphthoate
Synonyms
methyl 6-bromonaphthalene-2-carboxylate;Adap-int B;ADAPALENE RC A;Adapalene IMpurity G;Methyl 6-bromo-2-nap;Adapalene Impurity 4;6-BROMO-2-NAPHTHOIC AICD;Methyl-6-Bromo-2-Naphtoat;Methyl-6-bromo-2-naphtoate;6-Bromo-2-methyl napthoate
CBNumber
CB5426069
Molecular Formula
C12H9BrO2
Formula Weight
265.1
MOL File
33626-98-1.mol
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Methyl 6-bromo-2-naphthoate Property

Melting point:
123-126 °C (lit.)
Boiling point:
357.0±15.0 °C(Predicted)
Density 
1.492±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly)
form 
Crystalline Powder
color 
Off-white to cream or light brown
BRN 
2578943
InChIKey
JEUBRLPXJZOGPX-UHFFFAOYSA-N
CAS DataBase Reference
33626-98-1(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
20/21/22-34
Safety Statements 
24/25-45-36/37/39-27-26
WGK Germany 
3
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P370+P378In case of fire: Use … for extinction.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2827
Product name
Adapalene Related Compound A
Purity
certified reference material, pharmaceutical secondary standard
Packaging
100MG
Price
$608
Updated
2024/03/01
Sigma-Aldrich
Product number
539406
Product name
Methyl 6-bromo-2-naphthoate
Purity
98%
Packaging
5g
Price
$29.52
Updated
2024/03/01
Sigma-Aldrich
Product number
1011710
Product name
Adapalene Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1300
Updated
2024/03/01
TCI Chemical
Product number
B2202
Product name
Methyl 6-Bromo-2-naphthoate
Purity
>98.0%(GC)
Packaging
5g
Price
$51
Updated
2024/03/01
TCI Chemical
Product number
B2202
Product name
Methyl 6-Bromo-2-naphthoate
Purity
>98.0%(GC)
Packaging
25g
Price
$201
Updated
2024/03/01
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Methyl 6-bromo-2-naphthoate Chemical Properties,Usage,Production

Chemical Properties

Pale yellow or light brown powder

Uses

Methyl 6-Bromo-2-napthoate (Adapalene USP Related Compound A) is used in the synthesis of Adapalene, a retinoid specific for RARβ and RARγ receptors.

Uses

Methyl 6-bromo-2-naphthoate may be used to synthesize:

  • 6-vinyl-2-naphthalencarbaldehyde
  • methyl 6-(3-tert-butyl-4-methoxyphenyl)-2-naphthoate
  • methyl 6-[3-tert-butyl-4-[(tert-butyldiethylsilyl)oxy]-phenyl]-2-naphthoate
  • methyl 6-[3-(1-adamantyl)-4-[(tert-butyldimethylsilyl)-oxy]phenyl]-2-naphthoate
  • methyl 6-[3-(1-adamantyl)-4-[[(2,3-dimethyl-1,3-dioxolan-4-yl)methylloxy]phenyl]-2-naphthoate
  • 2-bromo-6-(bromomethyl)naphthalene

Uses

Methyl 6-Bromo-2-napthoate is used in the synthesis of Adapalene, a retinoid specific for RARβ and RARγ receptors.

General Description

Methyl 6-bromo-2-naphthoate undergoes aromatic Finkelstein reaction followed by hydrolysis to afford 6-iodo-2-naphthoic acid.

Methyl 6-bromo-2-naphthoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 6-bromo-2-naphthoate Suppliers

Shandong Xingshun New Material Co., Ltd.
Tel
0519-86464994 13382824994;
Fax
86-519-86463703
Email
gxy@xingshengtech.com
Country
China
ProdList
100
Advantage
65
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.
Tel
0513-82104991 18912868361
Fax
QQ1907456386
Email
sales2@btcpharm.com
Country
China
ProdList
1329
Advantage
58
Suzhou Junch Pharmaceutical Co., Ltd
Tel
18625279558; 18625279558
Email
sales01@junchpharm.com
Country
China
ProdList
12
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
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View Lastest Price from Methyl 6-bromo-2-naphthoate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Methyl 6-bromo-2-naphthoate 33626-98-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-14
Career Henan Chemical Co
Product
Methyl 6-bromo-2-naphthoate 33626-98-1
Price
US $1.00/KG
Min. Order
1G
Purity
98%
Supply Ability
100KG
Release date
2018-08-20
Career Henan Chemical Co
Product
Methyl 6-bromo-2-naphthoate 33626-98-1
Price
US $2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1 ton
Release date
2018-08-20

33626-98-1, Methyl 6-bromo-2-naphthoateRelated Search:


  • 6-Bromo-2-Naphtoic Acid Methyl Ester
  • 2-Bromo-6-naphthoic acid methylester
  • 6-BROMO-2-NAPHTHALENECARBOXYLIC ACID METHYL ESTER
  • 6-BROMO-2-NAPHTHOIC ACID METHYL ESTER
  • METHYL 6-BROMO-2-NAPHTHALENECARBOXYLATE
  • METHYL 6-BROMO-2-NAPHTHOATE
  • 2-Naphthoic acid, 6-bromo, methyl ester
  • Methyl-6-bromo-2-naphtoate
  • 6-BROMO-2-NAPHTHOIC AICD
  • 6-BROMO-2-NAPHTHOIC AICD, METHYL ESTER
  • Adapalene Impurity G (USP RC A)
  • 6-Bromo-2-methyl napthoate
  • Adapalene USP Related Compound A
  • 6-Bromonaphthalene-2-carboxylic acid methyl ester
  • Methyl 6-bromo-2-naphthoate,98%
  • Adapalene Related CoMpound A
  • Methyl-6-Bromo-2-Naphtoat
  • 6-Bromo-2-naphthalenecarboxylic Acid Methyl Ester 6-Bromo-2-naphthoic Acid Methyl Ester Methyl 6-Bromo-2-naphthalenecarboxylate
  • Adapalene IMpurity G
  • Methyl 6-bromo-2-nap
  • Adapalene Related Compound A (50 mg) (Methyl 6-bromo-2-naphthoate)
  • Methyl 6-broMo -2- napthoate
  • Methyl 6-broMo-2-naphthoate, 98% 5GR
  • Methyl 6-BroMo-2-naphthoate, 98.0%(GC)
  • methyl 6-bromonaphthalene-2-carboxylate
  • Adapalene Impurity 4
  • Adap-int B
  • Methyl 6-Bromo-2-naphthoate &gt
  • 2-Naphthalenecarboxylic acid, 6-bromo-, methyl ester
  • Adapalene Impurity 12(Adapalene Related Compound A)
  • Methyl 6-bromo-2-naphthoate CAS:33626-98-1
  • Adapalene Related Compound A (Methyl 6-bromo-2-naphthoate) (1011710)
  • 2-Naphthalenecarboxylic acid, 6-bromo-, methyl ester (9CI, ACI)
  • 6-bromo-2-Naphthalenecarboxylic acid methyl ester (9CI ACI)
  • Methyl 6-bromo-2-naphthote
  • ADAPALENE RC A
  • 33626-98-1
  • 3626-98-1
  • BrC10H6CO2CH3
  • C12H9BrO2
  • Naphthalene series
  • Building Blocks
  • C12 to C63
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • Others chemical reagents
  • C12 to C63
  • Carbonyl Compounds
  • Esters
  • API
  • Intermediates of Adapalene
  • Aromatic Esters
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • ADAPALENE
  • blocks
  • Bromides
  • Carboxes