5-METHOXYQUINOLINE
- Product Name
- 5-METHOXYQUINOLINE
- CAS No.
- 6931-19-7
- Chemical Name
- 5-METHOXYQUINOLINE
- Synonyms
- 5-METHOXYQUINOLINE;Quinoline, 5-methoxy-;5-METHOXYQUINOLINE ISO 9001：2015 REACH
- CBNumber
- CB7530124
- Molecular Formula
- C10H9NO
- Formula Weight
- 159.18
- MOL File
- 6931-19-7.mol
5-METHOXYQUINOLINE Property
- Boiling point:
- 282 °C(Press: 758 Torr)
- Density
- 1.130±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform
- form
- Oil
- pka
- 4.84±0.12(Predicted)
- color
- Brown
Safety
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- M267395
- Product name
- 5-Methoxyquinoline
- Packaging
- 100mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- W7912
- Product name
- 5-Methoxyquinoline
- Packaging
- 5g
- Price
- $188
- Updated
- 2021/12/16
- Product number
- 074651
- Product name
- 5-Methoxyquinoline
- Purity
- 95+%
- Packaging
- 25g
- Price
- $320
- Updated
- 2021/12/16
- Product number
- 074651
- Product name
- 5-Methoxyquinoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $46
- Updated
- 2021/12/16
- Product number
- W7912
- Product name
- 5-Methoxyquinoline
- Packaging
- 1g
- Price
- $91
- Updated
- 2021/12/16
5-METHOXYQUINOLINE Chemical Properties,Usage,Production
Chemical Properties
Brown Oil
Uses
5-Methoxyquinoline (cas# 6931-19-7) is a compound useful in organic synthesis.
Synthesis
578-67-6
74-88-4
6931-19-7
4.2 Synthesis of 5-methoxyquinoline (1) 5-Hydroxyquinoline (4.0 g, 27.6 mmol) was dissolved in anhydrous DMF (60 mL) under argon protection and cooled to 0 °C. NaH (1.33 g, 33.12 mmol, 60% mineral oil dispersion) was then slowly added. The reaction mixture was kept stirred at 0 °C for 30 min. Then, methyl iodide (4.7 g, 33.12 mmol) was added dropwise to the suspension and the reaction mixture was allowed to gradually warm up to room temperature with continued stirring for 30 min. Upon completion of the reaction, the reaction was quenched with 300 mL of water and then extracted with ether (6 x 100 mL). The organic layers were combined, washed sequentially with water and brine, dried with anhydrous Na2SO4, filtered and the solvent was concentrated under reduced pressure to give the brown oily target product 5-methoxyquinoline. Yield: 4.03 g (92%). 1H NMR (400 MHz, CDCl3) δ 8.95 (dd, J = 4.2, 2.0 Hz, 1H), 8.62 (dd, J = 8.4, 1.2 Hz, 1H), 7.74 (d, J = 8.0 Hz, 1H), 7.65 (t, J = 8.4 Hz, 1H), 7.42 (dd, J = 8.4, 4.4 Hz, 1H), 6.90 (d, J = 8.0 Hz, 1H), 4.05 (s, 3H). 13C NMR (100 MHz, CDCl3) δ 155.17, 150.66, 148.70, 130.81, 129.37, 121.58, 120.85, 120.19, 104.22, 55.76.
References
[1] European Journal of Medicinal Chemistry, 2015, vol. 101, p. 754 - 768
[2] Patent: KR101778938, 2017, B1. Location in patent: Paragraph 0147-0148; 0155; 0164-0166
[3] Dissertation , S. 23,
[4] Chemische Berichte, 1882, vol. 15, p. 1979
[5] Chemische Berichte, 1887, vol. 20, p. 731
5-METHOXYQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
5-METHOXYQUINOLINE Suppliers
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- sales@ajchem.in
- Country
- India
- ProdList
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- Advantage
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- info@chemsworth.com
- Country
- India
- ProdList
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View Lastest Price from 5-METHOXYQUINOLINE manufacturers
- Product
- 5-METHOXYQUINOLINE 6931-19-7
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-14