tert-Butyl 3-aminopyrrolidine-1-carboxylate
- Product Name
- tert-Butyl 3-aminopyrrolidine-1-carboxylate
- CAS No.
- 186550-13-0
- Chemical Name
- tert-Butyl 3-aminopyrrolidine-1-carboxylate
- Synonyms
- 1-BOC-3-AMINOPYRROLIDINE;CAS:186550-13-0;Methyl N-benzyl-3-;1-Boc-3-aminopyrro;3-AMINO-1-BOC-PYRROLIDINE;3-AMINO-1-N-BOC-PYRROLIDINE;1-N-BOC-3-AMINO-PYRROLIDINE;1-Boc-3-aminopyrrolidine 95%;1-Boc-3-aminopyrrolidine ,97%;DL-3-AMINO-1-N-BOC-PYRROLIDINE
- CBNumber
- CB7664832
- Molecular Formula
- C9H18N2O2
- Formula Weight
- 186.25
- MOL File
- 186550-13-0.mol
tert-Butyl 3-aminopyrrolidine-1-carboxylate Property
- Boiling point:
- 257.4±33.0 °C(Predicted)
- Density
- 1.022
- Flash point:
- 91°C
- refractive index
- 1.4710
- storage temp.
- 2-8°C
- pka
- 9.55±0.20(Predicted)
- form
- powder to lump to clear liquid
- color
- White or Colorless to Light yellow
- Sensitive
- Air Sensitive
- CAS DataBase Reference
- 186550-13-0(CAS DataBase Reference)
Safety
- Hazard Codes
- C,Xi,Xn
- Risk Statements
- 36/37/38-44-41-22
- Safety Statements
- 26-36/37/39
- RIDADR
- 2810
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 8
- PackingGroup
- Ⅲ
- HS Code
- 29339900
N-Bromosuccinimide Price
- Product number
- 706582
- Product name
- 1-Boc-3-aminopyrrolidine
- Purity
- 95%
- Packaging
- 1g
- Price
- $55.4
- Updated
- 2025/07/31
- Product number
- B3890
- Product name
- 3-Amino-1-(tert-butoxycarbonyl)pyrrolidine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $85
- Updated
- 2025/07/31
- Product number
- B3890
- Product name
- 3-Amino-1-(tert-butoxycarbonyl)pyrrolidine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $338
- Updated
- 2025/07/31
- Product number
- T204658
- Product name
- Tert-butyl3-Aminopyrrolidine-1-carboxylate
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 263596
- Product name
- 1-Boc-3-aminopyrrolidine
- Packaging
- 1g
- Price
- $319
- Updated
- 2021/12/16
tert-Butyl 3-aminopyrrolidine-1-carboxylate Chemical Properties,Usage,Production
Chemical Properties
Colorless low melting solid or liquid
Uses
1-Boc-3-Aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
862906-31-8
186550-13-0
Step (ii): preparation of tert-butyl 3-aminopyrrolidine-1-carboxylate (Formula 49) To a stirred solution of tert-butyl 3-hydroxypyrrolidine-1-carboxylate (Formula 48, 1.15 g, 4.16 mmol) in methanol (16.6 mL) was added 10% palladium/carbon catalyst (345 mg). The reaction mixture was stirred for 16 hours under a hydrogen atmosphere (hydrogen pressure applied via a double-layer balloon). Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad to remove the catalyst and the filtrate was concentrated under reduced pressure. The crude product was purified by silica gel fast column chromatography to afford the target compound tert-butyl 3-aminopyrrolidine-1-carboxylate (Formula 49, 640 mg) in 82% yield. 1H-NMR (CDCl3): δ 3.65-3.45 (m, 3H), 3.45-3.33 (m, 1H), 3.20-3.0 (m, 1H), 2.12-2.02 (m, 1H), 1.80-1.65 (m, 1H), 1.46 (s, 9H). Mass spectrum (m/z): 187 [M+H]+.
References
[1] Patent: WO2005/77924, 2005, A1. Location in patent: Page/Page column 76
[2] Patent: WO2011/30349, 2011, A1. Location in patent: Page/Page column 36-37
tert-Butyl 3-aminopyrrolidine-1-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
tert-Butyl 3-aminopyrrolidine-1-carboxylate Suppliers
- Tel
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- Fax
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- sales@abcheminc.com
- Country
- Canada
- ProdList
- 1128
- Advantage
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View Lastest Price from tert-Butyl 3-aminopyrrolidine-1-carboxylate manufacturers
- Product
- 1-Boc-3-aminopyrrolidine 186550-13-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-22
- Product
- tert-Butyl 3-aminopyrrolidine-1-carboxylate 186550-13-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 500kg
- Release date
- 2018-08-17