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RARECHEM AL BI 0500

Product Name
RARECHEM AL BI 0500
CAS No.
86239-00-1
Chemical Name
RARECHEM AL BI 0500
Synonyms
RARECHEM AL BI 0500;Ethyl 3-fluoro-4-Methylbenzoate;3-FLUORO-4-METHYLBENZOIC ACID ETHYL ESTER;Benzoic acid, 3-fluoro-4-methyl-, ethyl ester
CBNumber
CB7677876
Molecular Formula
C10H11FO2
Formula Weight
182.19
MOL File
86239-00-1.mol
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RARECHEM AL BI 0500 Property

Boiling point:
240.8±28.0 °C(Predicted)
Density 
1.108±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
Appearance
Light yellow to yellow Liquid
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific
Product number
PC911426
Product name
Ethyl3-fluoro-4-methylbenzoate
Purity
95%
Packaging
1g
Price
$110
Updated
2021/12/16
Apolloscientific
Product number
PC911426
Product name
Ethyl3-fluoro-4-methylbenzoate
Purity
95%
Packaging
5g
Price
$285
Updated
2021/12/16
Apolloscientific
Product number
PC911426
Product name
Ethyl3-fluoro-4-methylbenzoate
Purity
95%
Packaging
10g
Price
$470
Updated
2021/12/16
Rieke Metals
Product number
EE0266
Product name
3-Fluoro-4-methylbenzoicacidethylester
Packaging
1g
Price
$661
Updated
2021/12/16
Rieke Metals
Product number
EE0266
Product name
3-Fluoro-4-methylbenzoicacidethylester
Packaging
5g
Price
$1728
Updated
2021/12/16
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RARECHEM AL BI 0500 Chemical Properties,Usage,Production

Synthesis

64-17-5

350-28-7

86239-00-1

Thionyl chloride (3 mL) was added slowly and dropwise to a solution of 3-fluoro-4-methylbenzoic acid (13.23 g, 85.85 mmol) in anhydrous ethanol (200 mL) at 0 °C. The reaction mixture was warmed to 60 °C and stirred overnight. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure. The concentrate was diluted with dichloromethane and the resulting organic phase was washed sequentially with 1N sodium hydroxide solution (100 mL x 2). The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give ethyl 3-fluoro-4-methylbenzoate (15.02 g, 96% yield).

References

[1] Patent: WO2011/71565, 2011, A1. Location in patent: Page/Page column 163
[2] Patent: WO2010/93845, 2010, A1. Location in patent: Page/Page column 153
[3] Journal of Medicinal Chemistry, 1983, vol. 26, # 9, p. 1282 - 1293
[4] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 5, p. 1421 - 1425
[5] Patent: WO2009/145360, 2009, A1. Location in patent: Page/Page column 129-130

RARECHEM AL BI 0500 Preparation Products And Raw materials

Raw materials

Preparation Products

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RARECHEM AL BI 0500 Suppliers

Changzhou Anxuan Chemical, Co., Ltd.
Tel
13912302692 13912302692;
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0519-88064678
Email
sales@anxuanchem.com
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China
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4828
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58
BePharm Ltd
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400-685-9117
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021-51816740
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market@bepharm.com
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15081
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60
Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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China
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131957
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Aikon International Limited
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025-58859352 18068836627
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(5)02557626880
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dt3@aikonchem.com
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China
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15493
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Jinan Liheng Biotechnology Co., Ltd.
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0531-18763987518 18763987518
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levi@lihengpharm.com
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China
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1793
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Shanghai Jizhi Biochemical Technology Co. Ltd.
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4009004166/18616739031 18616739031
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3007523370@qq.com
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China
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52687
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Allfluoro pharmaceutical co. ltd.
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sales@allfluoro.com
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China
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ANHUI WITOP BIOTECH CO., LTD
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China
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Wuhan Ying Yuan Bei Biological Limited
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13349903920 13349903920;
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1540154086@qq.com
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China
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Shanghai Kaiwei Chemical Technology Co., Ltd.
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021-58461859 15821823057
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service@aiviche.com
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China
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