(-)-4-BROMOTETRAMISOLE OXALATE

Product Name: (-)-4-BROMOTETRAMISOLE OXALATE
CAS No.: 62284-79-1
Chemical Name: (-)-4-BROMOTETRAMISOLE OXALATE
Synonyms: (-)-p-Bromotetramisole oxalate;(S)-6-(p-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate;R 30402;6-BROMOLEVAMISOLE OXALATE;L-P-BROMOTETRAMISOLE OXALATE;(-)-P-BROMOLEVAMISOLE OXALATE;(-)-4-BROMOTETRAMISOLE OXALATE;Bromotetramisole, L(-) oxalate;(-)-4-BROMOTETRAMISOLE OXALATE;L-(-)-P-BROMOTETRAMISOLE OXALATE
CBNumber: CB7709111
Molecular Formula: C13H13BrN2O4S
Formula Weight: 373.22
MOL File: 62284-79-1.mol

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(-)-4-BROMOTETRAMISOLE OXALATE Property

Melting point:: 192 °C (dec.) (lit.)
Flash point:: 87℃
storage temp.: 2-8°C
solubility: Soluble in Water (up to 10 mg/ml)
form: liquid
color: White
optical activity: [α]25/D 104°, c = 0.5 in H2O
BRN: 4944883
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
InChI: InChI=1/C11H11BrN2S.C2H2O4/c12-9-3-1-8(2-4-9)10-7-14-5-6-15-11(14)13-10;3-1(4)2(5)6/h1-4,10H,5-7H2;(H,3,4)(H,5,6)/t10-;/s3
InChIKey: ZULBIBHDIQCNIS-MEQOOBBNNA-N
SMILES: C(=O)(O)C(=O)O.BrC1C=CC([C@@H]2N=C3SCCN3C2)=CC=1 |&1:11,r|

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Safety

Hazard Codes: Xn
Risk Statements: 21/22-36/37/38-20/21/22
Safety Statements: 24/25-36/37/39-26
WGK Germany: 3
F: 10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 190047
Product name: (?)-p-Bromolevamisole oxalate
Purity: 99%
Packaging: 25mg
Price: $155.06
Updated: 2025/07/31

Sigma-Aldrich

Product number: 190047
Product name: (?)-p-Bromolevamisole oxalate
Purity: 99%
Packaging: 100mg
Price: $419.36
Updated: 2025/07/31

Cayman Chemical

Product number: 18713
Product name: L-p-Bromotetramisole (oxalate)
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 18713
Product name: L-p-Bromotetramisole (oxalate)
Purity: ≥98%
Packaging: 5mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 18713
Product name: L-p-Bromotetramisole (oxalate)
Purity: ≥98%
Packaging: 10mg
Price: $109
Updated: 2024/03/01

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(-)-4-BROMOTETRAMISOLE OXALATE Chemical Properties,Usage,Production

Description

Four distinct human isoenzymes of alkaline phosphatase (AP) are known: intestinal (IAP), placental (PLAP), tissue non-specific (NSAP, also known as liver/bone/kidney AP), and germ cell AP (also known as placental-like AP, PLAP-like). L-p-Bromotetramisole is a cell-permeable inhibitor of all four human AP isoenzymes (K_is =18 and 56 μM for PLAP and NSAP, respectively). While PLAP is strongly inhibited by L-p-bromotetramisole, a second AP, possibly PLAP-like, shows only partial inhibition. L-p-Bromotetramisole has been shown to inhibit a tyrosine phosphatase from Drosophila and, as a result, is also used as a tyrosine phosphatase inhibitor.

Chemical Properties

white to light yellow crystal powde

Uses

L-p-Bromotetramisole Oxalate or (-)-p-Bromotetramisole Oxalate is a potent inhibitor of alkaline phosphatase.

Biochem/physiol Actions

(-)-p-Bromolevamisole oxalate inhibits L-isoforms of alkaline phosphatases.

target

alkaline phosphatase

References

[1] J S KOVACH D J S P A Svingen. Levamisole potentiation of fluorouracil antiproliferative activity mimicked by orthovanadate, an inhibitor of tyrosine phosphatase.[J]. JNCI Journal of the National Cancer Institute, 1992, 84 7: 515-519. DOI:10.1093/jnci/84.7.515
[2] J LUO. Role of protein phosphatases in the activation of CFTR (ABCC7) by genistein and bromotetramisole.[J]. American journal of physiology. Cell physiology, 2000, 279 1: C108-19. DOI:10.1152/ajpcell.2000.279.1.c108
[3] B M SCHER. The phosphatase inhibitors, orthovanadate and levamisole, inhibit induction of erythroid differentiation and abrogate the associated inhibition of glycolysis.[J]. International journal of oncology, 1998, 12 5: 987-996. DOI:10.3892/ijo.12.5.987

(-)-4-BROMOTETRAMISOLE OXALATE Preparation Products And Raw materials

Raw materials

Preparation Products

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(-)-4-BROMOTETRAMISOLE OXALATE Suppliers

China 93 Germany 2 India 1 Japan 1 South Korea 1 Switzerland 3 United Kingdom 4 United States 29 Global 134

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View Lastest Price from (-)-4-BROMOTETRAMISOLE OXALATE manufacturers

Dideu Industries Group Limited

Product: (-)-4-BROMOTETRAMISOLE OXALATE 62284-79-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-18

Career Henan Chemical Co

Product: (-)-4-BROMOTETRAMISOLE OXALATE 62284-79-1
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-02-01

62284-79-1, (-)-4-BROMOTETRAMISOLE OXALATERelated Search:

SALUBRINAL PRL-3 INHIBITOR I NSC 663284 Imazapic-ammonium Levamisole 2-(4-Bromophenyl)ethylamine (R)-(+)-1-(4-BROMOPHENYL)ETHYLAMINE 4-Bromobenzylamine 4-Bromo-alpha-phenethylamine (-)-4-BROMOTETRAMISOLE OXALATE (+)-P-BROMOTETRAMISOLE OXALATE S-ETHYLISOTHIOUREA HYDROBROMIDE 2-(METHYLTHIO)-2-IMIDAZOLINE 1,2-Ethanediamine,N2,N2-dimethyl-1-phenyl-,(1S)-(9CI) N,N'-DIMETHYLCARBAMIMINOTHIOIC ACID METHYL ESTER 2-(METHYLTHIO)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROBROMIDE 2-(ETHYLTHIO)-2-IMIDAZOLINE (2-AMINO-2-PHENYLETHYL)DIMETHYLAMINE

(-)-p-Bromolevamisole oxalate Ready Made Solution

(-)-p-Bromotetramisole oxalate【(S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate】

L-(-)-P-BROMOTETRAMISOLE OXALATE

L-P-BROMOTETRAMISOLE OXALATE

(-)-P-BROMOTETRAMISOLE OXALATE SALT

(-)-P-BROMOLEVAMISOLE OXALATE

R 30402

(S)-(-)-4-BROMOTETRAMISOLE OXALATE

(-)-(S)-6-(4-BROMOPHENYL)-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE OXALATE

S(-)-6-(4-BROMOPHENYL)-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE OXALATE

6-BROMOLEVAMISOLE OXALATE

(-)-6(4-BROMOPHENYL)-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE ETHANEDIOATE OXALATE SALT

(-)-4-BROMOTETRAMISOLE OXALATE

(S)-6-(p-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate

(-)-4-bromotetramisole oxalate salt

6-(4-Bromophenyl)-2,3,5,6-tetrahydro-(6S)-imidazo[2,1-b]thiazole,ethanedioate (1:1)

(-)-p-Bromotetramisole oxalate salt, 6-Bromolevamisole oxalate salt, (S)-(-)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate salt

(-)-4-Bromotetramisole oxalate, 6-Bromolevamisole oxalate, S(-)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate

L(-)-p-Bromotetramisole oxalate,99%

(-)-p-Bromotetramosole Oxalate Salt

(-)-4-BROMOTETRAMISOLE OXALATE USP/EP/BP

(-)-p-Bromotetramisole oxalate

Bromotetramisole, L(-) oxalate

(-)-p-Bromotetramisole Oxalate, 10 mM in DMSO

(?)-<i>p</i>-Bromolevamisole oxalate

(-) - Tetrabromoimidazole Oxalate

(-)-4-BROMOTETRAMISOLE OXALATE

62284-79-1

C13H13BrN2SO4

C11H11BrN2SC2H2O4

Specific inhibitor of nonspecific alkaline phosphatase

Chiral Building Blocks

Asymmetric Synthesis

Heterocyclic Building Blocks

Thiazoles

Inhibitors

chiral

API