ChemicalBook > CAS DataBase List > (-)-4-BROMOTETRAMISOLE OXALATE

(-)-4-BROMOTETRAMISOLE OXALATE

Product Name
(-)-4-BROMOTETRAMISOLE OXALATE
CAS No.
62284-79-1
Chemical Name
(-)-4-BROMOTETRAMISOLE OXALATE
Synonyms
(-)-P-BROMOTETRAMISOLE OXALATE;(-)-p-Bromotetramisole oxalate;(S)-6-(p-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate;R 30402;6-BROMOLEVAMISOLE OXALATE;L-P-BROMOTETRAMISOLE OXALATE;(-)-P-BROMOLEVAMISOLE OXALATE;(-)-4-BROMOTETRAMISOLE OXALATE;Bromotetramisole, L(-) oxalate;(-)-4-BROMOTETRAMISOLE OXALATE
CBNumber
CB7709111
Molecular Formula
C13H13BrN2O4S
Formula Weight
373.22
MOL File
62284-79-1.mol
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(-)-4-BROMOTETRAMISOLE OXALATE Property

Melting point:
192 °C (dec.) (lit.)
Flash point:
87℃
storage temp. 
2-8°C
solubility 
Soluble in Water (up to 10 mg/ml)
form 
liquid
color 
White
optical activity
[α]25/D 104°, c = 0.5 in H2O
BRN 
4944883
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
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Safety

Hazard Codes 
Xn
Risk Statements 
21/22-36/37/38-20/21/22
Safety Statements 
24/25-36/37/39-26
WGK Germany 
3
F 
10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
190047
Product name
(?)-p-Bromolevamisole oxalate
Purity
99%
Packaging
25mg
Price
$68.4
Updated
2024/03/01
Sigma-Aldrich
Product number
190047
Product name
(?)-p-Bromolevamisole oxalate
Purity
99%
Packaging
100mg
Price
$462
Updated
2024/03/01
Cayman Chemical
Product number
18713
Product name
L-p-Bromotetramisole (oxalate)
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
18713
Product name
L-p-Bromotetramisole (oxalate)
Purity
≥98%
Packaging
5mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
18713
Product name
L-p-Bromotetramisole (oxalate)
Purity
≥98%
Packaging
10mg
Price
$109
Updated
2024/03/01
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(-)-4-BROMOTETRAMISOLE OXALATE Chemical Properties,Usage,Production

Description

Four distinct human isoenzymes of alkaline phosphatase (AP) are known: intestinal (IAP), placental (PLAP), tissue non-specific (NSAP, also known as liver/bone/kidney AP), and germ cell AP (also known as placental-like AP, PLAP-like). L-p-Bromotetramisole is a cell-permeable inhibitor of all four human AP isoenzymes (Kis =18 and 56 μM for PLAP and NSAP, respectively). While PLAP is strongly inhibited by L-p-bromotetramisole, a second AP, possibly PLAP-like, shows only partial inhibition. L-p-Bromotetramisole has been shown to inhibit a tyrosine phosphatase from Drosophila and, as a result, is also used as a tyrosine phosphatase inhibitor.

Chemical Properties

white to light yellow crystal powde

Uses

L-p-Bromotetramisole Oxalate or (-)-p-Bromotetramisole Oxalate is a potent inhibitor of alkaline phosphatase.

Biochem/physiol Actions

(-)-p-Bromolevamisole oxalate inhibits L-isoforms of alkaline phosphatases.

target

alkaline phosphatase

References

1) Kovach?et al. (1992),?Levamisole potentiation of fluorouracil antiproliferative activity mimicked by orthovanadate, an inhibitor of tyrosine phosphatase; J. Natl. Cancer Inst.,?84?515 2) Luo et al. (2000),?Role of protein phosphatases in the activation of CTFR (ABCC7) by genistein and bromotetramisole;?Am. J. Physiol. Cell Physiol.,?279?C108 3) Scher?et al.?(1998),?The phosphatase inhibitors, orthovanadate and levamisole, inhibit induction of erythroid differentiation and abrogate the associated inhibition of glycolysis; Int. J. Oncol.,?12?987

(-)-4-BROMOTETRAMISOLE OXALATE Preparation Products And Raw materials

Raw materials

Preparation Products

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(-)-4-BROMOTETRAMISOLE OXALATE Suppliers

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View Lastest Price from (-)-4-BROMOTETRAMISOLE OXALATE manufacturers

Dideu Industries Group Limited
Product
(-)-4-BROMOTETRAMISOLE OXALATE 62284-79-1
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-18
Career Henan Chemical Co
Product
(-)-4-BROMOTETRAMISOLE OXALATE 62284-79-1
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-02-01

62284-79-1, (-)-4-BROMOTETRAMISOLE OXALATERelated Search:

SALUBRINAL PRL-3 INHIBITOR I NSC 663284 Imazapic-ammonium Levamisole 2-(4-Bromophenyl)ethylamine (R)-(+)-1-(4-BROMOPHENYL)ETHYLAMINE 4-Bromobenzylamine 4-Bromo-alpha-phenethylamine (-)-4-BROMOTETRAMISOLE OXALATE (+)-P-BROMOTETRAMISOLE OXALATE S-ETHYLISOTHIOUREA HYDROBROMIDE 2-(METHYLTHIO)-2-IMIDAZOLINE 1,2-Ethanediamine,N2,N2-dimethyl-1-phenyl-,(1S)-(9CI) N,N'-DIMETHYLCARBAMIMINOTHIOIC ACID METHYL ESTER 2-(METHYLTHIO)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROBROMIDE 2-(ETHYLTHIO)-2-IMIDAZOLINE (2-AMINO-2-PHENYLETHYL)DIMETHYLAMINE

  • (-)-p-Bromolevamisole oxalate Ready Made Solution
  • (-)-p-Bromotetramisole oxalate【(S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate】
  • L-(-)-P-BROMOTETRAMISOLE OXALATE
  • L-P-BROMOTETRAMISOLE OXALATE
  • (-)-P-BROMOTETRAMISOLE OXALATE
  • (-)-P-BROMOTETRAMISOLE OXALATE SALT
  • (-)-P-BROMOLEVAMISOLE OXALATE
  • R 30402
  • (S)-(-)-4-BROMOTETRAMISOLE OXALATE
  • (-)-(S)-6-(4-BROMOPHENYL)-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE OXALATE
  • S(-)-6-(4-BROMOPHENYL)-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE OXALATE
  • 6-BROMOLEVAMISOLE OXALATE
  • (-)-6(4-BROMOPHENYL)-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE ETHANEDIOATE OXALATE SALT
  • (-)-4-BROMOTETRAMISOLE OXALATE
  • (S)-6-(p-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate
  • (-)-4-bromotetramisole oxalate salt
  • 6-(4-Bromophenyl)-2,3,5,6-tetrahydro-(6S)-imidazo[2,1-b]thiazole,ethanedioate (1:1)
  • (-)-p-Bromotetramisole oxalate salt, 6-Bromolevamisole oxalate salt, (S)-(-)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate salt
  • (-)-4-Bromotetramisole oxalate, 6-Bromolevamisole oxalate, S(-)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate
  • L(-)-p-Bromotetramisole oxalate,99%
  • (-)-p-Bromotetramosole Oxalate Salt
  • (-)-4-BROMOTETRAMISOLE OXALATE USP/EP/BP
  • (-)-p-Bromotetramisole oxalate
  • Bromotetramisole, L(-) oxalate
  • (-)-4-BROMOTETRAMISOLE OXALATE
  • 62284-79-1
  • C13H13BrN2SO4
  • C11H11BrN2SC2H2O4
  • Specific inhibitor of nonspecific alkaline phosphatase
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Heterocyclic Building Blocks
  • Thiazoles
  • Inhibitors
  • chiral