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(-)-4-BROMOTETRAMISOLE OXALATE

Product Name
(-)-4-BROMOTETRAMISOLE OXALATE
CAS No.
62284-79-1
Chemical Name
(-)-4-BROMOTETRAMISOLE OXALATE
Synonyms
(-)-P-BROMOTETRAMISOLE OXALATE;(-)-p-Bromotetramisole oxalate;(S)-6-(p-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate;R 30402;6-BROMOLEVAMISOLE OXALATE;L-P-BROMOTETRAMISOLE OXALATE;(-)-P-BROMOLEVAMISOLE OXALATE;(-)-4-BROMOTETRAMISOLE OXALATE;Bromotetramisole, L(-) oxalate;(-)-4-BROMOTETRAMISOLE OXALATE
CBNumber
CB7709111
Molecular Formula
C13H13BrN2O4S
Formula Weight
373.22
MOL File
62284-79-1.mol
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(-)-4-BROMOTETRAMISOLE OXALATE Property

Melting point:
192 °C (dec.) (lit.)
Flash point:
87℃
storage temp. 
2-8°C
solubility 
Soluble in Water (up to 10 mg/ml)
form 
liquid
color 
White
optical activity
[α]25/D 104°, c = 0.5 in H2O
BRN 
4944883
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
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Safety

Hazard Codes 
Xn
Risk Statements 
21/22-36/37/38-20/21/22
Safety Statements 
24/25-36/37/39-26
WGK Germany 
3
10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
190047
Product name
(?)-p-Bromolevamisole oxalate
Purity
99%
Packaging
25mg
Price
$68.4
Updated
2024/03/01
Sigma-Aldrich
Product number
190047
Product name
(?)-p-Bromolevamisole oxalate
Purity
99%
Packaging
100mg
Price
$462
Updated
2024/03/01
Cayman Chemical
Product number
18713
Product name
L-p-Bromotetramisole (oxalate)
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
18713
Product name
L-p-Bromotetramisole (oxalate)
Purity
≥98%
Packaging
5mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
18713
Product name
L-p-Bromotetramisole (oxalate)
Purity
≥98%
Packaging
10mg
Price
$109
Updated
2024/03/01
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(-)-4-BROMOTETRAMISOLE OXALATE Chemical Properties,Usage,Production

Description

Four distinct human isoenzymes of alkaline phosphatase (AP) are known: intestinal (IAP), placental (PLAP), tissue non-specific (NSAP, also known as liver/bone/kidney AP), and germ cell AP (also known as placental-like AP, PLAP-like). L-p-Bromotetramisole is a cell-permeable inhibitor of all four human AP isoenzymes (Kis =18 and 56 μM for PLAP and NSAP, respectively). While PLAP is strongly inhibited by L-p-bromotetramisole, a second AP, possibly PLAP-like, shows only partial inhibition. L-p-Bromotetramisole has been shown to inhibit a tyrosine phosphatase from Drosophila and, as a result, is also used as a tyrosine phosphatase inhibitor.

Chemical Properties

white to light yellow crystal powde

Uses

L-p-Bromotetramisole Oxalate or (-)-p-Bromotetramisole Oxalate is a potent inhibitor of alkaline phosphatase.

Biochem/physiol Actions

(-)-p-Bromolevamisole oxalate inhibits L-isoforms of alkaline phosphatases.

target

alkaline phosphatase

References

1) Kovach?et al. (1992),?Levamisole potentiation of fluorouracil antiproliferative activity mimicked by orthovanadate, an inhibitor of tyrosine phosphatase; J. Natl. Cancer Inst.,?84?515 2) Luo et al. (2000),?Role of protein phosphatases in the activation of CTFR (ABCC7) by genistein and bromotetramisole;?Am. J. Physiol. Cell Physiol.,?279?C108 3) Scher?et al.?(1998),?The phosphatase inhibitors, orthovanadate and levamisole, inhibit induction of erythroid differentiation and abrogate the associated inhibition of glycolysis; Int. J. Oncol.,?12?987

(-)-4-BROMOTETRAMISOLE OXALATE Preparation Products And Raw materials

Raw materials

Preparation Products

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(-)-4-BROMOTETRAMISOLE OXALATE Suppliers

Zhangshu Hongyuan Biomedical Technology Co., Ltd.
Tel
19195036662
Email
335864138@qq.com
Country
China
ProdList
159
Advantage
58
Zhangshu Chenxi Biotechnology Co., Ltd
Tel
19070905030
Email
cx@chenxisw.com
Country
China
ProdList
57
Advantage
58
Hefei Leo Biotechnology Co., Ltd
Tel
15715515222
Email
leo@leo-sw.com
Country
China
ProdList
129
Advantage
58
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4554
Advantage
62
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4727
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
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View Lastest Price from (-)-4-BROMOTETRAMISOLE OXALATE manufacturers

Dideu Industries Group Limited
Product
(-)-4-BROMOTETRAMISOLE OXALATE 62284-79-1
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-18
Career Henan Chemical Co
Product
(-)-4-BROMOTETRAMISOLE OXALATE 62284-79-1
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-02-01

62284-79-1, (-)-4-BROMOTETRAMISOLE OXALATERelated Search:


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  • 62284-79-1
  • C13H13BrN2SO4
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  • Specific inhibitor of nonspecific alkaline phosphatase
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Heterocyclic Building Blocks
  • Thiazoles
  • Inhibitors
  • chiral
  • API