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D-PANTOTHENIC ACID

Product Name
D-PANTOTHENIC ACID
CAS No.
79-83-4
Chemical Name
D-PANTOTHENIC ACID
Synonyms
PANTOTHENATE;Pantothenic;pantothenicacid;(R)-Pantothenate;(R)-3-(2,4-Dihydroxy-3,3-diMethylbutanaMido)propanoic acid;D-VITAMIN B(5);Ca pantothenaat;d-pantothenicaci;D-PANTOTHENIC ACID;(R)-pantothenicaci
CBNumber
CB7716522
Molecular Formula
C9H17NO5
Formula Weight
219.24
MOL File
79-83-4.mol
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D-PANTOTHENIC ACID Property

Melting point:
178-179℃
alpha 
D25 +37.5°
Boiling point:
360.05°C (rough estimate)
Density 
1.266
refractive index 
1.4315 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Oil to Gel
pka
4.30±0.10(Predicted)
color 
Colourless
Stability:
Hygroscopic
InChI
InChI=1/C9H17NO5/c1-9(2,5-11)7(14)8(15)10-4-3-6(12)13/h7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13)/t7-/s3
InChIKey
GHOKWGTUZJEAQD-KPOCXSGKNA-N
SMILES
[C@H](O)(C(=O)NCCC(=O)O)C(C)(C)CO |&1:0,r|
LogP
-0.856 (est)
EPA Substance Registry System
D-Pantothenic acid (79-83-4)
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Safety

Hazardous Substances Data
79-83-4(Hazardous Substances Data)
Toxicity
LD50 intraperitoneal in mouse: 1443mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
462022
Product name
Pantothenic Acid
Packaging
1g
Price
$340
Updated
2021/12/16
TRC
Product number
P190305
Product name
PantothenicAcid(TechnicalGrade,ContainsLactone)
Packaging
2.5g
Price
$1115
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
41875
Product name
PantothenicAcid
Packaging
250g
Price
$675
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000861
Product name
D-PANTOTHENIC ACID
Purity
95.00%
Packaging
10MG
Price
$885.31
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000861
Product name
D-PANTOTHENIC ACID
Purity
95.00%
Packaging
50MG
Price
$1491.68
Updated
2021/12/16
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D-PANTOTHENIC ACID Chemical Properties,Usage,Production

Physical properties

Pantothenic acid is composed of β-alanine joined to 2,4-dihydroxy-3,3- dimethylbutyric acid via an amide linkage. The molecule has an asymmetric center, and only the R-enantiomer, usually called D-(+)pantothenic acid, is biologically active and occurs naturally. Appearance: pantothenic acid is a yellow, viscous oil. Its calcium and other salts, however, are colorless crystalline substances; calcium pantothenate is the main product of commerce. Solubility: neither form is soluble in organic solvents, but each is soluble in water and ethanol. Stability: aqueous solu tions of pantothenic acid are unstable when heated under acidic or alkaline conditions

Originator

Panto-250 , Bio-Tech Pharmacal

Uses

Pantothenic Acid is a member of the B complex vitamins; essential vitamin for the biosynthesis of coenzyme A in mammalian cells. Occurs ubiquitously in all animal and plant tissue. The richest common source is liver, but jelly of the queen bee contains 6 times as much as liver. Rice bran and molasses are other good sources.

Uses

Labelled Pantothenic Acid

Uses

Vitamin B5 is water-soluble. It is required for proper growth and maintenance of the body and is involved in body processes such as energy release from carbohydrates and metabolism of fatty acids. It is relatively stable through storage and is found in liver, eggs, and meat.

Definition

ChEBI: (R)-pantothenic acid is a pantothenic acid having R-configuration. It has a role as an antidote to curare poisoning, a human blood serum metabolite and a geroprotector. It is a vitamin B5 and a pantothenic acid. It is a conjugate acid of a (R)-pantothenate.

Manufacturing Process

Isobutylaldehyde reacted with formaldehyde in the presence potassium chromate as a result 2,2-dimethyl-3-hydroxy-propanal was obtained.
The 2,2-dimethyl-3-hydroxy-propanal was treated by sodium cyanide so 2,4dihydroxy-3,3-dimethyl-butironitrile was prepared.
The 2,4-dihydroxy-3,3-dimethyl-butironitrile was treated hydrochloric acid and D,L-3-hydroxy-4,4-dimethyl-dihydro-furan-2-one (D,L-pantolacton) was obtained. The racemic mixture of D- and L-pantolactons was a division of Dand L- isomers by the adding of α-phenylethylamine. So D-pantolacton was isolated.
Acrylic acid contacted with NH3and β-alanine was obtained.
D-Pantalacton reacted with β-alanine as a result 3-(2,4-dihydroxy-3,3dimethyl-butyrylamino)-propanoic acid was produced

brand name

Calpan (BASF); Pantholin (Lilly).

Therapeutic Function

Vitamin

Safety Profile

Moderately toxic by subcutaneous and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx.

D-PANTOTHENIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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D-PANTOTHENIC ACID Suppliers

kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
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View Lastest Price from D-PANTOTHENIC ACID manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
D-PANTOTHENIC ACID 79-83-4
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-06
Henan Suikang Pharmaceutical Co.,Ltd.
Product
D-PANTOTHENIC ACID 79-83-4
Price
US $0.00/kg
Min. Order
25kg
Purity
99.0%
Supply Ability
10tons
Release date
2024-04-28
Hebei Longbang Technology Co., Ltd
Product
D-PANTOTHENIC ACID 79-83-4
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-04-28

79-83-4, D-PANTOTHENIC ACIDRelated Search:


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  • 4-dihydroxy-3,3-dimethyl-1-oxobutyl)-n-((r)-beta-alanin
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  • (-)-3-[[(S)-2,4-Dihydroxy-3,3-dimethylbutyryl]amino]propionic acid
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  • 3-[(2R)-2,4-dihydroxy-3,3-diMethylbutanaMido]propanoic acid
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  • β-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, (R)-
  • β-Alanine, N-[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]-
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  • Colesevelam Impurity 11
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  • C1613C2H28D4CaN2O10
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  • Pharmaceuticals
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  • 79-83-4